About the Lab
The lab employs intracranial recordings and direct brain stimulation to investigate electrophysiology in the human brain. We work with neurosurgical patients undergoing intracranial activity monitoring with stereo-electroencephalography (sEEG) for clinical reasons (drug-resistant epilepsy patients; patients enrolled in clinical trials for DBS implants). We leverage the opportunity to record directly from the human brain to further our understanding of the neural signatures underlying perceptual and cognitive processes. We also study the effects of neurostimulation across cortical and subcortical structures.
Lab Members
Lab Projects
- Mattar L, Shah S, Chamakura L, Oswalt D, Zhang Y, Devara D, Kang J, Jourahmad Z, Jafri R, Liu G, Adkinson J, Danstrom I, Fan X, Reed Y, Bijanki K, Goldman A, Lin L, Krishnan V, Provenza N, Watrous A, Heilbronner S, Sheth. S, Banks G, Bartoli E. Neural signatures and personalized neuromodulation in a subject experiencing context-dependent inhibitory control deficits. medRxiv [Preprint] 2025 June 06.
- Kang J, Mattar L, Vergara J, Gobo V, Rey HG, Heilbronner SR, Watrous AJ, Hayden BY, Sheth SA, Bartoli E. Parietal cortex is recruited by frontal and cingulate areas to support action monitoring and updating during stopping. Neuroimage 2025 Jul 15; 315: 121288. doi: 10.1016/j.neuroimage.2025.121288.
- Hacker C, Mocchi M, Xiao J, Metzger B, Adkinson J, Pascuzzi B, Mathura R, Oswalt D, Watrous A, Bartoli E, Allawala A, Pirtle V, Fan X, Danstrom I, Shofty B, Banks G, Zhang Y, Armenta-Salas M, Mirpour K, Provenza N, Mathew S, Cohn J, Borton D, Goodman W, Pouratian N, Sheth S, Bijanki K. Aperiodic (1/f) Neural Activity Robustly Tracks Symptom Severity Changes in Treatment-Resistant Depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Vol 10(2), (2024); doi: 10.1016/j.bpsc.2024.10.019.
- Mocchi M, Bartoli E, Magnotti J, de Gee, J, Metzger B, Pscuzzi B, Mathura R, Pulapaka S, Goodman, W, Sheth S, McGinley M, Bijanki K. Aperiodic spectral slope tracks the effects of brain state on saliency responses in the human auditory cortex. Sci Rep 14, 30751 (2024); doi: 10.1038/s41598-024-80911-3.
- Kabotyanski K, Yi H, Hingorani R, Robinson B, Cowley H, Fifer M, Wester B, Lamichhane B, Sabharwal A, Allawala A, Rajesh S, Diab N, Mathura R, Pirtle V, Adkinson J, Watrous A, Bartoli E, Xiao J, Banks G, Mathew S, Goodman W, PitkowX, Pouratian N, Hayden B, Provenza N, Sheth S. [10.1016/j.brs.2024.10.007]Towards objective, temporally resolved neurobehavioral predictors of emotional state. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, Volume 17( 6), 1208 – 1212 (2024); doi: 10.1016/j.brs.2024.10.007.
- Xiao J, Adkinson JA, Myers J, Allawala A, Mathura R, Pirtle V, Najera R, Provenza N, Bartoli E, Watrous A, Oswalt D, Gadot R, Anand A, Shofty B, Mathew S, Goodman W, Pouratian N, Pitkow X, Bijanki K, Hayden B, Sheth SA. Beta activity in human anterior cingulate cortex mediates reward biases. Nat Commun 15, 5528 (2024); doi: 10.1038/s41467-024-49600-7.
- Huang H, Adkinson J, Jensen M, Hasen M, Danstrom I, Bijanki K, Gregg N, Miller K, Sheth S, Hermes D, Bartoli E. Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data. Journal of Neuroscience Methods. 2025 Jul 5; 419:110461.
- Bartoli E, Devara E, Huy D, Rabinovich R, Mathura R, Anand A, Pascuzzi B, Adkinson J, Kenett Y, Bijanki K, Sheth S, Shofty B. Default mode network electrophysiological dynamics and causal role in creative thinking. Brain 2024 October; 147:10. doi:10.1093/brain/awae199
- Schmid W, Danstrom IA, Crespo Echevarria M, Adkinson J, Mattar L, Banks GP, Sheth SA, Watrous AJ, Heilbronner SR, Bijanki KR, Alabastri A, Bartoli E. A biophysically constrained brain connectivity model based on stimulation-evoked potentials. J Neurosci Methods. 2024 Mar 5;405:110106. doi: 10.1016/j.jneumeth.2024.110106.
- Ayyoubi AH, Fazli Besheli B, Quach MM, Gavvala JR, Goldman AM, Swamy CP, Bartoli E, Curry DJ, Sheth SA, Francis DJ, Ince NF. Benchmarking signal quality and spatiotemporal distribution of interictal spikes in prolonged human iEEG recordings using CorTec wireless brain interchange. Sci Rep. 2024 Feb 8;14(1):2652. doi: 10.1038/s41598-024-52487-5.
- Sheth SA, Shofty B, Allawala A, Xiao J, Adkinson JA, Mathura RK, Pirtle V, Myers J, Oswalt D, Provenza NR, Giridharan N, Noecker AM, Banks GP, Gadot R, Najera RA, Anand A, Devara E, Dang H, Bartoli E, Watrous A, Cohn J, Borton D, Mathew SJ, McIntyre CC, Goodman W, Bijanki K, Pouratian N. Stereo-EEG-guided network modulation for psychiatric disorders: Surgical considerations. Brain Stimul. 2023 Nov-Dec;16(6):1792-1798. doi: 10.1016/j.brs.2023.07.057.
- Aponik-Gremillion L, Chen YY, Bartoli E, Koslov SR, Rey HG, Weiner KS, Yoshor D, Hayden BY, Sheth SA, Foster BL. Distinct population and single-neuron selectivity for executive and episodic processing in human dorsal posterior cingulate. Elife. 2022 Sep 28;11. doi: 10.7554/eLife.80722.
- Foster BL, Bartoli E. Aligning evidence for the genesis of visual gamma oscillations. PLoS Biol.2022 Jun;20(6):e3001701. doi: 10.1371/journal.pbio.3001701.
- Li Y, Bosking W, Beauchamp MS, Sheth SA, Yoshor D, Bartoli E, Foster BL. Biased Orientation and Color Tuning of the Human Visual Gamma Rhythm. J Neurosci. 2022 Feb 9;42(6):1054-1067. doi: 10.1523/JNEUROSCI.1085-21.2021.
- Chen YY, Aponik-Gremillion L, Bartoli E, Yoshor D, Sheth SA, Foster BL. Stability of ripple events during task engagement in human hippocampus. Cell Rep. 2021 Jun 29;35(13):109304. doi: 10.1016/j.celrep.2021.109304.
- Bartoli E, Bosking W, Foster BL. Seeing Visual Gamma Oscillations in a New Light. Trends Cogn Sci. 2020 Jul;24(7):501-503. doi: 10.1016/j.tics.2020.03.009.
- Bartoli E, Bosking W, Chen Y, Li Y, Sheth SA, Beauchamp MS, Yoshor D, Foster BL. Functionally Distinct Gamma Range Activity Revealed by Stimulus Tuning in Human Visual Cortex. Curr Biol.2019 Oct 21;29(20):3345-3358.e7. doi: 10.1016/j.cub.2019.08.004.
- Bartoli E, Conner CR, Kadipasaoglu CM, Yellapantula S, Rollo MJ, Carter CS, Tandon N. Temporal Dynamics of Human Frontal and Cingulate Neural Activity During Conflict and Cognitive Control. Cereb Cortex. 2018 Nov 1;28(11):3842-3856. doi: 10.1093/cercor/bhx245.
- Bartoli E, Aron AR, Tandon N. Topography and timing of activity in right inferior frontal cortex and anterior insula for stopping movement. Hum Brain Mapp. 2018 Jan;39(1):189-203. doi: 10.1002/hbm.23835.
Full List of Publications
https://www.ncbi.nlm.nih.gov/myncbi/eleonora.bartoli.1/bibliography/public/
Contact Us
One Baylor Plaza, Room S100A, Houston Texas 77030
E-mail: bartoli@bcm.edu