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  1. Baylor College of Medicine
  2. Academic Centers
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  4. Research
  5. Ethical Legal Implications of Psychedelics in Society Program (ELIPSIS)
  • Philosophical Bioethics
  • Ethical Legal Implications of Psychedelics in Society Program (ELIPSIS)
  • Mission to Enhance Ethics Education, Outreach, and Research in Space (METEORS)

Ethical Legal Implications of Psychedelics in Society Program (ELIPSIS)

Psychedelics Bioethics and Health Policy

Overview

Psychedelics have the ability to profoundly and positively transform healthcare, and interest in the medical use of psychedelics to treat mental health has gone mainstream. But the therapeutic potential of substances like Psilocybin, LSD, and MDMA brings a unique set of ethical and policy challenges and questions that must be researched and addressed right now.Dr. Amy McGuire, Leon Jaworski Professor of Biomedical Ethics and Director of the Center for Medical Ethics and Health Policy at Baylor College of Medicine and Dr. Lynnette Astrid Averill, Ph.D are building a new research program supported through private funding focused on ethical and policy issues related to psychedelic research, which includes: 

  • What are the evidence-based policies and ethical guidelines needed to ensure safe an effective psychedelic research and use?
  • How do we ensure adherence to these policies/guidelines and mitigate the risks of potential misuse?
  • What are the legal implications for psychedelics, including federal drug scheduling, professional licensure, and overall standards of medical care?
  • How can we understand and measure the psychosocial impacts of psychedelic research and use?

Promising research on the therapeutic use of psychedelics came to an abrupt halt more than 50 years ago, in response to political pressure and concerns about unregulated recreational use and unethical research practices. Over the past few years, we have seen a resurgence of interest in studying the therapeutic potential of psychedelics, but the future remains unclear. In order to avoid history repeating itself, it is essential that we conduct high-quality research and develop evidence- based guidelines to inform future policy decisions.

Psychedelic therapy is an emerging mental health wellness.

– USA Today

Our Unique Role

The Center for Medical Ethics and Health at Baylor College of Medicine is building a research program focused on ethics, policy, and the implementation of psychedelic research. We have long been a leader in understanding and advancing research in critical issues in biomedicine, with over 5.9M in active research grants. Our multi-disciplinary teams of experts in bioethics, social science, biomedicine, health policy, and the law have successful track records of studying the ethical, legal, and social implications (ELSI) of emerging biomedical science, including advanced genetic sequencing and neurotechnologies, and translating our findings into real-world solutions.

We collaborate with large networks of investigators and clinicians within the Texas Medical Center, the largest medical center in the world, and beyond, and are well-equipped to identify opportunities and address challenges in real-time as they arise.

Get Involved

The Psychedelic Revolution Is Coming. Psychiatry May Never Be the Same.

– The New York Times
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Support our mission to grow a program focused on ethics and policy psychedelic research. Donate now!

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Advocate for ethical practices among the psychedelic community.

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Connect us to those in your network interested in collaborating in our work.

Investors See Far Out Profits in Psychedelic Medicine.

– The Wall Street Journal
  • Philosophical Bioethics
  • Ethical Legal Implications of Psychedelics in Society Program (ELIPSIS)
  • Mission to Enhance Ethics Education, Outreach, and Research in Space (METEORS)

Contact Us

E-mail bioethics@bcm.edu

Program News

Press Releases

  • New policies needed to maximize psychedelics’ therapeutic potential
  • Baylor launches program focused on bioethics and health policy of psychedelics research

In the News

  • Psychedelics and who should be able to use them - WBUR
  • The Therapy Part of Psychedelic Therapy Is a Mess - Wired
  • “When the policy gets ahead of the science, it's challenging”: 5 Questions for bioethicist Amy McGuire - The Microdose

TRIPS Study: FAQs about Psychedelic Retreats

In 2024, the ELIPSIS program launched the Trustworthy, Responsible Integration of Psychedelics in Society (TRIPS) Study to analyze unregulated psychedelic retreats in the U.S., focusing on their ethical, legal, and social implications. Supported by the Ortus Foundation, this project reviewed available evidence and participants’ experiences to provide practical guidance.

Note: These FAQs are for informational purposes only and should not be taken as medical or legal advice.

Download FAQs

Sample Publications

McGuire AL, Lynch HF, Grossman LA, Cohen IG. Pressing regulatory challenges for psychedelic medicine. Science. 2023;380(6643):347-350. doi:10.1126/science.adg1324. Full article.

McGuire AL, et al. Developing an Ethics and Policy Framework for Psychedelic Clinical Care: A Consensus Statement. JAMA Netw Open. 2024 Jun 3;7(6):e2414650. doi: 10.1001/jamanetworkopen.2024.14650. PMID: 38833254. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2819456

Neitzke-Spruill L, Beit C, Averill LA, McGuire AL. Supportive Touch in Psychedelic Assisted Therapy. Am J Bioeth. 2025 Jan;25(1):29-39. doi: 10.1080/15265161.2024.2433428. Epub 2025 Jan 13. PMID: 39804300. Supportive Touch in Psychedelic Assisted Therapy: The American Journal of Bioethics: Vol 25 , No 1 

Neitzke-Spruill L, Devenot N, Sisti D, Averill LA, McGuire AL. Bio-Psycho-Spiritual Perspectives on Psychedelics: Clinical and Ethical Implications. Perspect Biol Med. 2024;67(1):117-142. doi: 10.1353/pbm.2024.a919715. PMID: 38662068. Project MUSE - Bio-Psycho-Spiritual Perspectives on Psychedelics: Clinical and Ethical Implications

Psychedelics

Psychedelics and who should be able to use them

Podcast - wbur.org

Features a discussion with Amy Lynn McGuire, professor of biomedical ethics. Director of the Center for Medical Ethics and Health Policy at Baylor College of Medicine. Listen to the podcast.

Can creating moments of meaning improve mental health?

Amy McGuire | TEDxBaylorCollegeofMedicine

We are in the midst of a mental health crisis and in need of a public health response. But there may be something that each of us can do to improve our collective mental health.

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Should psychedelic drugs be used to treat PTSD and depression in veterans?

This article discusses the potential of using psychedelics to treat PTSD, depression, and other disorders, as well as the dilemmas of applying such treatment.  View article.

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