Latest News in Genetics

Evenings with Genetics spotlights osteogenesis imperfectaSep 10, 2019
On Tuesday, Sept. 17, Evenings with Genetics will highlight the current research and resources available to those living with osteogenesis imperfecta.
Postnatal overnutrition linked to agingAug 26, 2019
Researchers at Baylor College of Medicine have found a new answer to an old question: how can overnutrition during infancy lead to long-lasting health problems such as diabetes?
Study builds roadmap for collecting, sequencing genetic dataAug 22, 2019
The National Institutes of Health has conducted a four-year study to harmonize and standardize clinical genetic reporting. 
Loss of ataxin-1 gene linked to Alzheimer’s disease riskAug 22, 2019
A collaborative study reveals the ataxin-1 gene, which is known to cause the rare neurodegenerative disease called spinocerebellar ataxia type 1 (SCA1), can increase the risk of Alzheimer’s disease in a mouse model of the condition.
p53 mutations in cancer patients shed light on gene’s functionJul 30, 2019
Researchers at Baylor College of Medicine have conducted a  study of TP53 mutations to better understand the processes leading to the inactivation of this important gene. 
Dr. Huda Zoghbi to receive genetics leadership award at national meetingJul 22, 2019
The American Society of Human Genetics (ASHG) has honored Dr. Huda Zoghbi with the 2019 Victor A. McKusick Leadership Award.
Moderate dose of novel form of stress promotes longevityJul 10, 2019
A team of researchers found that a newly described form of stress called chromatin architectural defect triggers a response in cells that could lead to a longer life.
Olga Dudchenko named to MIT Technology Review's TR35 Jun 27, 2019
Olga Dudchenko, genomics researcher and postdoctoral associate at Baylor College of Medicine and Rice University, has been named to MIT Technology Review magazine's 2019 list of Innovators Under 35.
Grant from Chan Zuckerberg Initiative to support growth of Human Cell Atlas Jun 21, 2019
A team of researchers have been awarded a grant by the Chan Zuckerberg Initiative to support the Human Cell Atlas project.
Reanalysis of molecular data yields new genetic diagnosesJun 21, 2019
A genomic strategy implemented by researchers at Baylor College of Medicine can efficiently increase the molecular diagnostic rate of undiagnosed diseases.

Genetics in the News: April 2019 - June 2019

Olga Dudchenko named one of the MIT Technology Review "35 Innovators under 35"

Olga Dudchenko, with the Aiden Laboratory, was named one of the 35 Innovators under 35 by MIT Technology Review for her work in creating a faster and cheaper way to sequence a genome.

Patent issued for osteoarthritis gene-therapy product

A potentially disease-modifying therapy for osteoarthritis (OA) has reached a key milestone. A U.S. patent has been issued for FX201, a gene-therapy product candidate licensed by Flexion Therapeutics based on work led by Baylor College of Medicine researchers.

A treasure map to understanding epigenetic causes of disease

In a report published in Genome Biology, Dr. Robert Waterland and his team have identified special regions of the genome where a blood sample can be used to infer epigenetic regulation throughout the body, allowing scientists to test for epigenetic causes of disease

New computational tool improves gene identification

In a study that appears in Bioinformatics, a team led by researchers at Baylor College of Medicine has developed a new bioinformatics tool that analyzes CRISPR pooled screen data and identifies candidates for potentially relevant genes with greater sensitivity and accuracy than other existing methods. 

Colon cancer proteins, genes uncover potential treatments

A multi-institutional study, published in Cell, supports comprehensive characterization of tumor tissues as a means to guide further research leading to early diagnostic strategies and new treatments.

Research improves understanding of cell-cell communication

The National Institutes of Health Common Funds Extracellular RNA Communication Consortium, which includes researchers from Baylor College of Medicine, created the exRNA Atlas resource, the first detailed catalog of human exRNAs in bodily fluids. The study that details this resource appears in the journal Cell.

Dr. Hsiao-Tuan Chao named new McNair Scholar

Dr. Hsiao-Tuan Chao, assistant professor of pediatrics and molecular and human genetics at Baylor College of Medicine has been named the newest McNair Scholar.

New strategy fights bacterial antibiotic resistance

In a study in Molecular Cell, researchers in the Rosenberg lab at Baylor College of Medicine, reveal how bacteria evolve mutations that lead to antibiotic resistance and that this process can be hindered with an FDA-approved drug.

Genetics in the News: January 2019 - March 2019

Unveiling disease-causing genetic changes in chromosome 17

In a study appearing in Cell, a group of researchers in the Lupski Lab at Baylor College of Medicine have discovered that there is much more to 17p11.2 syndromes than deletions and duplications.

High-fructose corn syrup promotes intestinal tumors in mice

In a study, published in Science, researchers at Baylor College of Medicine and Weill Cornell Medicine showed that consuming a daily modest amount of high-fructose corn syrup accelerates the growth of intestinal tumors in APC-model mice. 

Discovery improves understanding of Lou Gehrig's disease

A collaborative study led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute of Texas Children’s Hospital improves our understanding of how amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, develops.

Two Independent Mechanisms Involved in Tuberous Sclerosis

In a study published in a February issue of the Proceedings of the National Academy of Sciences, researchers at Baylor College of Medicine and Texas Children's Hospital, found another mechanism involved in the development of Tuberous Sclerosis. 

Researchers uncover intracellular longevity pathway

Dr. Meng Wang and her colleagues report in the January issue of Developmental Cell, the discovery of an intracellular pathway that mediates metabolic adjustments that promote health and longevity in the worm, Caenorhabditis elegans

Discovery explains breast cancer cells’ ability to adapt, survive

A team led by researchers at Baylor College of Medicine has discovered that breast cancer cells can shift between two forms of the cell surface molecule CD44: CD44s and CD44v.

Bacteria help discover human cancer-causing proteins

A team led by researchers from Baylor College of Medicine and University of Texas at Austin applied an unconventional approach that used bacteria to discover human proteins that can lead to DNA damage and promote cancer. Reported in the journal Cell, the study also proposes biological mechanisms by which these proteins can cause damage to DNA, opening possibilities for future cancer treatments.