Postgraduate scientists in the Department of Integrative Physiology play a critical role in research activities as well as in mentoring students.
We are committed to helping these postdoctoral researchers gain the skills and experience required to fully develop into the next generation of scientific leaders. In addition to providing cutting-edge research training, we offer a career development program to complement the extensive program offered by the College to help our postdoctoral researchers achieve their individual career goals.
Friendly and collaborative atmosphere
Our department includes faculty at all stages of their career. It offers a friendly and collaborative environment for research and training that fosters communication between faculty and postdoctoral researchers. The weekly Thursday lunch following student and postdoc seminars allows discussions of any topic in an informal setting between faculty and postdoctoral researchers.
Faculty committee to accompany the postdoctoral researchers throughout their time in the department
Five faculty members form the postdoctoral faculty committee to organize, with the current postdoctoral researchers, activities to improve the professional development of our trainees. These committee members are Ross Poché, Ph.D. (director and an alumnus of our postdoctoral program), Christine Beeton, Ph.D., Frank Horrigan, Ph.D., William Lagor, Ph.D., and Joshua Wythe, Ph.D.
Seminar series
Presenting research results in a coherent and interesting way is crucial to all scientists, regardless of their long-term career goals. To help develop and improve these skills, all postdoctoral researchers give an annual seminar to the department. Most give a 30 min seminar (20 min talk + questions) but four trainees selected annually based on merit will be invited to give a 60 min seminar (45 min talk + questions) during the invited faculty seminar series.
Career development committee to guide postdoctoral researchers towards successful careers
Our postdoctoral researchers have diverse backgrounds, diverse research interests, and diverse career goals. To help them develop the requirements for these careers, we offer individualized training. The Postdoc-Faculty forum is a series of quarterly roundtable discussions. Faculty members and other professionals in various fields share their experiences and discuss major career steps, such as choosing a career path, navigating the job search, preparing for an interview, or balancing research and family life. Besides working in close collaboration with a faculty in research laboratory within the department, each postdoctoral researcher establishes a committee of faculty and other professionals he/she meets with regularly to ensure individualized career development.
An award for postdoctoral researchers who obtain a fellowship
Whether postdoctoral researchers want to develop your career in academia or in the private sector, writing funding applications is a crucial skill to develop and nurture.
To help our postdoctoral researchers write the best funding applications, we organize study sections to evaluate and provide constructive criticism on their applications before submission to the funding agency. In order to recognize their efforts and excellence, the Graduate School of Biomedical Sciences offers a Dean’s Award for Excellence to postdoctoral researchers who obtain a nationally/regionally competitive fellowship after Nov. 1, 2014. Those eligible postdocs will be provided a one-time gift of $3,000.
Ross Poché, Ph.D., Director
Email: poche@bcm.edu
Telephone: (832) 788-5835
Fax: (713) 798-3475
Publications
Syed SH, Coughlin AJ, Garcia MD, Wang S, West JL, Larin KV, Larina IV. Optical coherence tomography guided microinjections in live mouse embryos: high-resolution targeted manipulation for mouse embryonic research. J Biomed Opt. 2015 May;20(5):051020.
Kulkarni PM, Rey-Villamizar N, Merouane A, Sudheendran N, Wang S, Garcia M,Larina IV, Roysam B, Larin KV. Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data. Quant Imaging Med Surg. 2015 Feb;5(1):125-35.
Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015 Jan 29;5:4.
Loehr JA, Abo-Zahrah R, Pal R, Rodney GG. Sphingomyelinase promotes oxidant production and skeletal muscle contractile dysfunction through activation of NADPH oxidase. Front Physiol. 2015 Jan 21;5:530.
Wu Y, Rasmussen TP, Koval OM, Joiner ML, Hall DD, Chen B, Luczak ED, Wang Q, Rokita AG, Wehrens XH, Song LS, Anderson ME. The mitochondrial uniporter controls fight or flight heart rate increases. Nat Commun. 2015 Jan 20;6:6081.
Aschar-Sobbi R, Izaddoustdar F, Korogyi AS, Wang Q, Farman GP, Yang F, Yang W, Dorian D, Simpson JA, Tuomi JM, Jones DL, Nanthakumar K, Cox B, Wehrens XH, Dorian P, Backx PH. Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα. Nat Commun. 2015 Jan 19;6:6018.
Yang X, Wang T, Lin X, Yue X, Wang Q, Wang G, Fu Q, Ai X, Chiang DY, Miyake CY,Wehrens XH, Chang J. Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling. Circ Res. 2015 Jan 2;116(1):e1-e10.
Tanner MR, Hu X, Huq R, Tajhya RB, Sun L, Khan FS, Laragione T, Horrigan FT, Gulko PS, Beeton C. KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis. Arthritis Rheumatol. 2015 Jan;67(1):96-106.
Shirokova N, Kang C, Fernandez-Tenorio M, Wang W, Wang Q, Wehrens XH, Niggli E. Oxidative stress and ca(2+) release events in mouse cardiomyocytes. Biophys J. 2014 Dec 16;107(12):2815-27.
Udan RS, Piazza VG, Hsu CW, Hadjantonakis AK, Dickinson ME. Quantitative imaging of cell dynamics in mouse embryos using light-sheet microscopy. Development. 2014 Nov;141(22):4406-14.
Wang W, Landstrom AP, Wang Q, Munro ML, Beavers D, Ackerman MJ, Soeller C,Wehrens XH. Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice. Am J Physiol Heart Circ Physiol. 2014 Nov 1;307(9):H1317-26.
Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C, Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL. Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function. J Biol Chem. 2014 Sep 12;289(37):25556-70.
Pal R, Palmieri M, Loehr JA, Li S, Abo-Zahrah R, Monroe TO, Thakur PB, Sardiello M,Rodney GG. Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy. Nat Commun. 2014 Jul 16;5:4425.
Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, Wang G, Skapura D, Voigt N, Dobrev D, Wehrens XH. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res. 2014 Jul 1;103(1):178-87.
Chaudhury A, Kongchan N, Gengler JP, Mohanty V, Christiansen AE, Fachini JM, Martin JF, Neilson JR. A piggyBac-based reporter system for scalable in vitro and in vivo analysis of 3' untranslated region-mediated gene regulation. Nucleic Acids Res. 2014 Jun;42(10):e86.
Wang S, Lopez AL 3rd, Morikawa Y, Tao G, Li J, Larina IV, Martin JF, Larin KV. Noncontact quantitative biomechanical characterization of cardiac muscle using shear wave imaging optical coherence tomography. Biomed Opt Express. 2014 May 30;5(7):1980-92.
Koshy S, Huq R, Tanner MR, Atik MA, Porter PC, Khan FS, Pennington MW, Hanania NA, Corry DB, Beeton C. Blocking KV1.3 channels inhibits Th2 lymphocyte function and treats a rat model of asthma. J Biol Chem. 2014 May 2;289(18):12623-32.
Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XH. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25;129(12):1276-85.
Voigt N, Heijman J, Wang Q, Chiang DY, Li N, Karck M, Wehrens XH, Nattel S, Dobrev D. Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation. 2014 Jan 14;129(2):145-56.
Pal R, Monroe TO, Palmieri M, Sardiello M, Rodney GG. Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells. FEBS Lett. 2014 Jan 31;588(3):472-81.
Postdoc Funding Opportunities
This list was compiled to help our postdoctoral researchers identify potential sources of funding. Although we try to keep this list updated, note that the list may not be exhaustive and deadlines may change
- Amyotrophic Lateral Sclerosis Association
- Autism Speaks
- Craig H. Neilsen Foundation
- Epilepsy Foundation
- Eppendorf and Science Prize for Neurobiology
- Brain and Behavior Research Foundation
- National Ataxia Foundation
- National Multiple Sclerosis Foundation
- National Tourette Syndrome Association
- Parkinson’s Disease Foundation
- Burroughs Wellcome Fund
- Department of Agriculture – National Institute of Food and Agriculture
- Department of Defense
- Helen Hay Whitney Foundation
- Human Frontiers Science Program
- Life Sciences Research Foundation
- The Intelligence Community
- National Institutes of Health
- National Science Foundation
- Sigma Delta Epsilon – Graduate Women in Science
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