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Department of Molecular and Cellular Biology
Department of Molecular and Cellular News
New insight into breast cancer resistance to hormone therapy - MAR 5, 2020 New findings suggest that a therapeutic approach must combine two different drugs, a SERD to degrade ER and a MEK inhibitor to inhibit Ras downstream signaling, in order to effectively treat neurofibromin-depleted ER+ breast cancer.
Unanticipated response to estrogen at the single cell level - JAN 15, 2020 A team of researchers led by Baylor College of Medicine found that individual mammalian cells in a population fail to respond synchronously to estrogen stimulation.
Mechanism reprograms breast cancer to become metastatic - DEC 11, 2019 A researchers haves unveiled a novel mechanism that helps explain how endocrine-resistant breast cancer acquires metastatic behavior.
Dr. Carolyn Smith named dean of Graduate School - NOV 20, 2019 The Baylor College of Medicine Board of Trustees voted today to appoint Dr. Carolyn Smith dean of the Graduate School of Biomedical Sciences.
Brain circuit connects feeding, mood in response to stress - SEP 5, 2019 Researchers looked into the possibility of crosstalk between eating and mood and discovered a brain circuit in mouse models that connects the feeding and the mood centers of the brain.
Dr. Peggy Goodell named chair of cell biology - AUG 27, 2019 Dr. Margaret “Peggy” Goodell has been named chair of the Department of Molecular and Cellular Biology at Baylor College of Medicine by the College’s Board of Trustees.
Folic acid reduces risk of defects linked to dolutegravir - JUL 23, 2019 Researchers at Baylor College of Medicine suspected that folic acid could be a part of the puzzle of dolutegravir’s negative side effects.
A treasure map to understanding epigenetic causes of disease - JUN 3, 2019 Researchers have determined a unique fraction of the genome that scientists should focus on. Their report, which provides a “treasure map” to accelerate research in epigenetics and human disease, was published today in Genome Biology.
Dr. David Moore elected into National Academy of Sciences - APR 30, 2019 Dr. David Moore, professor of molecular and cellular biology, medicine and molecular and human genetics at Baylor College of Medicine, has been elected to the National Academy of Sciences.
Discovery explains breast cancer cells’ ability to adapt, survive - JAN 28, 2019 A team led by researchers at Baylor College of Medicine has discovered that breast cancer cells can shift between two forms of the cell surface molecule CD44, CD44s and CD44v.
Global grants aim to help scientists understand tumor behavior - JAN 23, 2019 A multidisciplinary, international team of scientists has been awarded Cancer Research UK’s Grand Challenge, an ambitious series of £20 million global grants tackling some of the toughest questions in cancer research.
Unexpected link found between feeding, memory brain areas - JAN 22, 2019 The search for a mechanism that could explain how the protein complex NCOR1/2 regulates memory has revealed an unexpected connection between the feeding and the memory centers of the brain.
Dr. Kjersti Aagaard awarded mentor award from Nature - DEC 19, 2018 Dr. Kjersti Aagaard has been honored with a 2018 Nature Award for Mentoring in Science.
Researchers find missplicing Scn5a alters cardiac function - SEP 28, 2018 A new study shows that reproducing in mice the missplicing of gene Scn5a observed in patients with myotonic dystrophy type 1(DM1) recapitulates defects in cardiac function present in the patients.
Math meets biology to uncover unexpected biorhythms - SEP 19, 2018 A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.
Dr. Cheryl Lyn Walker receives Outstanding Investigator Award - AUG 6, 2018 Dr. Cheryl Lyn Walker has been awarded an Outstanding Investigator Award (R35) from the National Cancer Institute (NCI).
Scientists develop new approach to understand Huntington’s - JUN 20, 2018 A team of scientists developed a new approach that provides a better understanding of Huntington’s disease and suggested new directions for developing therapeutic interventions.
Grant to fund study on gender differences in aortic disease - JAN 26, 2018 Baylor was selected to join the newly formed Strategically Focused Vascular Disease Research Network of the American Heart Association to focus on understanding the pathobiology underlying the differences in aortic disease between men and women.
G-quadruplex regulates breast cancer-associated gene - DEC 21, 2017 Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development of novel therapeutic strategies to control cancer growth in the future.
Regulating asprosin levels might help control appetite, weight - NOV 6, 2017 Studies into the asprosin hormone open an intriguing possibility for developing novel treatments for overweight people.
Heparin stimulates food intake, body weight gain in mice - SEP 5, 2017 New research suggests that heparin could be a potential target for drugs regulating appetite and weight control.