*Limited Institutional Submission Opportunity requiring LOI and Internal Selection
Deadlines:
- Internal Submission Deadlines: 12 p.m. on Nov. 18, 2025
- Funding Organization's nomination deadline: 4 p.m. (CT) on Dec. 5, 2025
- Funding Organization’s application deadline: 3 p.m. (CT) on Jan. 9, 202
Purpose & Funding amount:
The Dan L Duncan Comprehensive Cancer Center (DLDCCC) has been invited to participate in the 2025 V Foundation Adult Translational Cancer Research funding opportunity. This grant opportunity is restricted to adult cancer research in the preclinical or translational space with a focus on bench-to-bedside strategies. This RFA includes two grant mechanisms:
Translational Cancer Research Grant
Open to faculty conducting adult cancer research in the preclinical or translational stage with clear clinical relevance within three years. Eligible projects may move a novel strategy into a human clinical trial or use clinical specimens to develop biomarkers or test mechanisms. A detailed biostatistical or bioinformatics plan is mandatory. Research areas NOT included in this scope are epidemiology, behavioral science, and health services research.
Funding: $800,000 over four years ($200,000/year)
All-Star Translational Cancer Research Grant
Open only to prior V Foundation grantees who have completed or are in the final year of a previous award. This mechanism supports high-risk, high-reward, transformative research that significantly advances cancer understanding or treatment. Projects must focus on adult cancer in the preclinical or translational space with a bench-to-bedside approach, showing direct human relevance within three years. A detailed biostatistical or bioinformatics plan is mandatory.
Funding : $1,000,000 over five years ($200,000 per year).
Nomination Limit:
DLDCCC can submit up to two nominations— one Translational and one All-Star, so applicants are encouraged to carefully review the eligibility criteria in the attached RFAs and All-Star Eligibility Guide before applying.
Submission:
If interested, please upload following to the InfoReady system by Tuesday, Nov. 18, 2025 at 12 p.m.
- a one-page letter of intent (LOI) for the project
- current NIH Biosketch
The LOI will be reviewed by the DLDCCC-appointed panel to make the final decision on nominations. If chosen, you will have until Jan. 9 at 3 p.m. CT to submit the full application to the foundation.
Format Requirement:
Ensuring all materials are uploaded as a single PDF file. Please name your LOI file as follows:
NAME OF SPONSOR_PI LAST NAME_LOI
Example: CPRIT_SMITH_LOI
Please see the attached document for more details.
For questions, please contact the DLDCCC grants team at DLDCCCgrants@bcm.edu.
