Human Tissue Acquisition and Pathology Core Publications


Selected Publications Supported by Human Tissue Acquisition and Pathology Core




Krieger KL, Gohlke JH, Lee KJ, Piyarathna DWB, Castro PD, Jones JA, Ittmann MM, Gassman NR, Sreekumar A. Repair-Assisted Damage Detection Reveals Biological Disparities in Prostate Cancer between African Americans and European Americans. Cancers (Basel). 2022 Feb 17;14(4):1012. doi: 10.3390/cancers14041012. PMID: 35205762; PMCID: PMC8870190.

Stur E, Corvigno S, Xu M, Chen K, Tan Y, Lee S, Liu J, Ricco E, Kraushaar D, Castro P, Zhang J, Sood AK. Spatially resolved transcriptomics of high-grade serous ovarian carcinoma. iScience. 2022 Feb 14;25(3):103923. doi: 10.1016/j.isci.2022.103923. eCollection 2022 Mar 18. PMID: 35252817 PMCID: PMC8891954

Jang HJ, Lee HS, Yu W, Ramineni M, Truong CY, Ramos D, Splawn T, Choi JM, Jung SY, Lee JS, Wang DY, Sederstrom JM, Pietropaolo M, Kheradmand F, Amos CI, Wheeler TM, Ripley RT, Burt BM. Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment. Cancer Res. 2022 Jul 18;82(14):2593-2609. doi: 10.1158/0008-5472.CAN-21-3506. PMID: 35709756 PMCID: PMC9296613




Kumar V, McClelland M, Nguyen J, De Robles G, Ittmann M, Castro P, Mercola D, Jia Z, Rahmatpanah F. Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry. Cancers (Basel). 2021 Dec 17;13(24):6347. doi: 10.3390/cancers13246347. PMID: 34944967; PMCID: PMC8699453.

Mao H, Li L, Fan Q, Angelini A, Saha PK, Coarfa C, Rajapakshe K, Perera D, Cheng J, Wu H, Ballantyne CM, Sun Z, Xie L, Pi X. Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nat Commun. 2021 Sep 6;12(1):5296. doi: 10.1038/s41467-021-25673-6. PMID: 34489478; PMCID: PMC8421392.

Mirkin S, Simon JA, Liu JH, Archer DF, Castro PD, Graham S, Bernick B, Komm B. Evaluation of endometrial progesterone receptor expression after 12 weeks of exposure to a low-dose vaginal estradiol insert. Menopause. 2021 May 28;28(9):998-1003. doi: 10.1097/GME.0000000000001801. PMID: 34054104; PMCID: PMC8386586.

Ravindran A, Piyarathna DWB, Gohlke J, Putluri V, Soni T, Lloyd S, Castro P, Pennathur S, Jones JA, Ittmann M, Putluri N, Michailidis G, Rajendiran TM, Sreekumar A. Lipid Alterations in African American Men with Prostate Cancer. Metabolites. 2021 Dec 22;12(1):8. doi: 10.3390/metabo12010008. PMID: 35050130; PMCID: PMC8779756.

Shao L, Wang J, Karatas O, Ittmann M. MEX3D is an oncogenic driver in prostate cancer. Prostate. 2021 Nov;81(15):1202-1213. doi: 10.1002/pros.24216. Epub 2021 Aug 29. PMID: 34455614; PMCID: PMC8460603.

Shen T, Wang W, Zhou W, Coleman I, Cai Q, Dong B, Ittmann MM, Creighton CJ, Bian Y, Meng Y, Rowley DR, Nelson PS, Moore DD, Yang F. MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT. J Clin Invest. 2021 Feb




Castaneda JM, Miyata H, Archambeault DR, Satouh Y, Yu Z, Ikawa M, Matzuk MM. Mouse t-complex protein 11 is important for progressive motility in sperm. Biol Reprod. 2020 Apr 15;102(4):852-862.

Chen J, Matatall KA, Feng X, Hormaechea-Agulla D, Maharjan M, Young N, King KY. Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment. Exp Hematol. 2020 Nov;91:39-45.e2. PMID: 32961298

Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, et al. CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer. Sci Rep. 2020;10(1):243. PMCID: 6959290.

Mullany LK, Rohira AD, Leach JP, Kim JH, Monroe TO, Ortiz AR, Stork B, Gaber MW, Sarkar P, Sikora AG, Rosengart TK, York B, Song Y, Dacso CC, Lonard DM, Martin JF, O'Malley BW. A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31353-31364. PMID: 33229578 PMCID: PMC7733826

Nakamura S, Shigeyama S, Minami S, Shima T, Akayama S, Matsuda T, Esposito A, Napolitano G, Kuma A, Namba-Hamano T, Nakamura J, Yamamoto K, Sasai M, Tokumura A, Miyamoto M, Oe Y, Fujita T, Terawaki S, Takahashi A, Hamasaki M, Yamamoto M, Okada Y, Komatsu M, Nagai T, Takabatake Y, Xu H, Isaka Y, Ballabio A, Yoshimori T. LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury. Nat Cell Biol. 2020 Oct;22(10):1252-1263. PMID: 32989250

Napolitano G, Di Malta C, Esposito A, de Araujo MEG, Pece S, Bertalot G, Matarese M, Benedetti V, Zampelli A, Stasyk T, Siciliano D, Venuta A, Cesana M, Vilardo C, Nusco E, Monfregola J, Calcagnì A, Di Fiore PP, Huber LA, Ballabio A. A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome. Nature. 2020 Sep;585(7826):597-602. PMID: 32612235

Sengal A, Velazquez J, Hahne MV, Burke T, Abhyankar H, Reyes RWI, Olea W, Scull BP, Eckstein OS, Bigenwald C, Bollard CM, Yu W, Merad M, McClain KL, Allen CE, Chakraborty R. Overcoming T cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH. Blood. 2020 Oct 19;blood.2020005867. PMID: 33075814