The Department of Neurosurgery advances the treatment of neurological disorders through its cutting-edge neurosurgery research programs based at Baylor College of Medicine and its hospital affiliates. These efforts include basic neuroscience research, translational research, and clinical research programs.

The department's many research programs are led by Michael S. Beauchamp, Ph.D., vice-chair of basic research, and Sameer Sheth, M.D., Ph.D., vice-chair of clinical research. Growth in research is a high priority, and new research faculty has been recruited and a new laboratory suite for neurosurgical research at Baylor has been constructed.

Our research programs are well supported by competitive National Institutes of Health (NIH), Department of Defense, Veteran’s Affairs Merit Award, and Patient-Centered Outcomes Research Institute grants. The vibrant collection of neurosurgical researchers forms the base for the department’s NIH R25 grant, which supports research education for our residents during their dedicated research year (R25NS070694, BAYLOR RESEARCH EDUCATION PROGRAM IN NEUROSURGERY, PI: Daniel Yoshor).

The past five years have also witnessed remarkable growth in our research programs. In 2015, the Baylor Department of Neurosurgery had $975,000 in NIH funding, ranking #25 in the nation (Blue Ridge). This year, the department is projected to receive approximately $7,000,000 in NIH grants, which should place us well within the top 10 for 2019. When this figure is combined with NIH grants based in the hospital affiliates that form our neurosurgery residency program, the total approaches $10 million and would rank in the top three in the nation.

NIH-Funded Projects

A sampling of the department’s NIH-funded projects is highlighted below:

PI: Michael S. Beauchamp
R01NS065395
NEURAL MECHANISMS OF OPTIMAL MULTISENSORY INTEGRATION

PI: Brett Foster
R00MH103479
SPATIOTEMPORAL INVESTIGATIONS OF PARIETAL CORTEX CONTRIBUTIONS TO EPISODIC MEMORY

PI: Brett Foster
R01MH116914
SENSORY REINSTATEMENT IN HUMAN NEOCORTEX

PI: Vladimir Didenko
R01NS082553
FRET PROBES FOR ANALYSIS OF SERPIN-MEDIATED APOPTOSIS IN FOCAL BRAIN ISCHEMIA

PI: Vladimir Didenko
R21EB022788
EXPRESS ASSAY FOR SPECIFIC FLUORESCENCE IMAGING OF APOPTOSIS VIA PHOSPATASE-ASSISTED TOPOLIGATION

PI: Vladimir Didenko
R21NS101620
IMAGING mRNA TURNOVER IN P-BODIES AND ITS APPLICATION TO BRAIN ISCHEMIA 

PI: Akash Patel
K08NS10247401 
ESTABLISHING THE GENOMIC LANDSCAPE OF HUMAN ATYPICAL MENINGIOMAS  

PI: Tatiana Schnur
R01DC014976
LANGUAGE AND NEURAL RECOVERY FROM STROKE: ROLE OF SELECTION AND WORKING MEMORY 

PI: Sameer Sheth
UH3NS10354901
DEEP BRAIN STIMULATION FOR DEPRESSION USING DIRECTIONAL CURRENT STEERING AN INDIVIDUALIZED NETWORK TARGETING

PI: Sameer Sheth
R01MH10670001A1
COGNITIVE CONTROL MECHANISMS IN HUMAN PREFRONTAL CORTEX

PI: Sameer Sheth
U01NS108923
MECHANISMS OF RAPID, FLEXIBLE COGNITIVE CONTROL IN HUMAN PREFRONTAL CORTEX

PI: Ashwin Viswanathan
R01NR018481
PERCUTANEOUS CORDOTOMY FOR PAIN PALLIATION IN ADVANCED CANCER

PI: Daniel Yoshor
R01EY023336
VISUAL FORM PERCEPTION PRODUCED BY ELECTRICALLY STIMULATING HUMAN VISUAL CORTEX

PI: Daniel Yoshor
R25NS070694
BAYLOR RESEARCH EDUCATION PROGRAM IN NEUROSURGERY