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Department of Integrative Physiology
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  1. Baylor College of Medicine
  2. Departments
  3. Integrative Physiology
  4. Research
  5. Cardiovascular Sciences
  • Biochemistry and Biophysics
  • Biomedical Imaging
  • Cardiovascular Sciences
  • Cell and Developmental Biology
  • Human Disease
  • Molecular Biology and Genetics
  • Neurophysiology

Cardiovascular Sciences Research

Cardiovascular research is one of the key areas of interest of the Department of Molecular Physiology and Biophysics. Research by our faculty members focuses on a variety of subjects including cardiovascular ion channels, calcium handling proteins, heart development, cardiac diseases such as cardiac arrhythmias, hypertrophy and heart failure, and multiple imaging modalities including magnetic resonance imaging, echocardiography, and confocal and multi-focal imaging.

Ground-breaking findings made in our department include the development of animal models for sudden infant death syndrome, the identification of new proteins involved in the development of atrial fibrillation and heart failure, the generation of new imaging modalities to study heart disease at the cellular and whole animal level, and the identification of the cause of heart stroke. These research programs are supported by substantial extramural grant support, and have led to publications of important new findings in high impact scientific journals.

Through the development of a state-of-the-art mouse phenotyping facility, our faculty and trainees are able to interrogate the effects of changes in the genome on cardiovascular and skeletal muscle function. Faculty and trainees in our department work closed by other cardiovascular scientists and clinicians at Baylor College of Medicine and affiliated hospitals. Our research efforts are well integrated within the larger cardiovascular community at BCM, and provide an excellent environment for collaborative research and strong training opportunities for graduate students and postdoctoral trainees.

Areas of Research

Cardiac Ion Channels

  • Ryanodine receptors
  • Intracellular calcium release

Cardiac Development

  • Angiogenesis
  • Heart morphogenesis

Heart Disease

  • Cardiac arrhythmias
  • Cardiac hypertrophy
  • Heart failure
  • Inflammation and cardiovascular disease

Imaging

  • Magnetic resonance imaging (MRI)
  • 2-photon microscopy
  • Ultrasound

Research Faculty: Cardiovascular Sciences

Beeton
Christine Beeton
Ph.D.
Professor
View profile
Dickinson
Mary E. Dickinson
Ph.D.
Adjunct Professor
View profile
Hamilton
Susan L Hamilton
Ph.D.
Professor and L. F. McCollum Chair in Molecular Physiology
View profile
Lagor
William R. Lagor
Ph.D.
Kyle and Josephine Morrow Endowed Professor
View profile
Larina
Irina V. Larina
Ph.D.
Professor and Kyle and Josephine Morrow Endowed Chair
View profile
Martin
James F Martin
M.D., Ph.D.
Vice Chairman/Professor
View profile
Pautler
Robia G Pautler
Ph.D.
Professor
View profile
Pedersen
Steen E Pedersen
Ph.D.
Associate Professor
View profile
Rodney Jr.
George Gerald Rodney Jr.
Ph.D.
Associate Professor
View profile
Wehrens
Xander Wehrens
M.D., Ph.D.
Juanita P. Quigley Endowed Chair in Cardiology
View profile

Trainees

Postdocs

  • Ge Tao, Ph.D.
  • Yang Xiao, Ph.D.

Graduate Students

  • Zhijuan Cao
  • Redwan Huq
  • John Leach
  • Lele Li
  • Ann Quick
  • Victor Piazza
  • Nejla Yosef
Department of Integrative Physiology
  • Biochemistry and Biophysics
  • Biomedical Imaging
  • Cardiovascular Sciences
  • Cell and Developmental Biology
  • Human Disease
  • Molecular Biology and Genetics
  • Neurophysiology

Contact

Phone 713–798–4700
Fax 713–798–3475
Email physiology@bcm.edu

Department of Molecular Physiology and Biophysics

Baylor College of Medicine One Baylor Plaza - BCM335 Houston, TX 77030

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