Susan L Hamilton, Ph.D.

Professor and L. F. McCollum Chair in Molecular Physiology

(713) 798-5704

susanh@bcm.edu

Professor and L. F. McCollum Chair in Molecular Physiology: Integrative Physiology
Baylor College of Medicine
Houston, TX, US

Member: Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Advanced Training from Columbia University College Of Physicians And Surgeons: 01/1976 - New York, NY, United States

Ph.D. from University Of Colorado School Of Medicine: 01/1976 - Denver, CO, United States

Skeletal Muscle Excitation-Contraction coupling, ryanodine receptors L-type Ca2+ Channels and diseases of skeletal muscle.

Hamilton Lab Web Site

VIICTR - Publications

Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. " AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. " Nat. Med.. 2012 ; 18 (2) : 244-51.
Pubmed PMID: 22231556.
Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E. " Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. " Neuron. 2008 Dec 10; 60 (5) : 832-45.
Pubmed PMID: 19081378.
Durham WJ, Aracena-Parks P, Long C, Rossi AE, Goonasekera SA, Boncompagni S, Galvan DL, Gilman CP, Baker MR, Shirokova N, Protasi F, Dirksen R, Hamilton SL. " RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. " Cell. 2008 Apr 4; 133 (1) : 53-65.
Pubmed PMID: 18394989.
Andronache Z, Hamilton SL, Dirksen RT, Melzer W. " A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice. " Proc. Natl. Acad. Sci. U.S.A.. 2009 Mar 17; 106 (11) : 4531-6.
Pubmed PMID: 19246389.