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Mouse Strains Available For Reporter Model Testing

Content
Common NameAlleleEditing 
Mechanism
Reporter
Ai9

Gt(ROSA)26Sortm9(CAG-tdTomato)Hze

NHEJtdTomato
Ai9–SpySauCas9

Gt(ROSA)26Sorem1(CAG-tdTomato)Jahe

NHEJtdTomato
Ai9-Cas12a

Gt(ROSA)26Sorem2(CAG-tdTomato)Jahe

NHEJtdTomato
Ai6

Gt(ROSA)26Sortm9(CAG-zsGreen)Hze

NHEJZsGreen
Ai6-HDR1

Gt(ROSA)26Sorem3(CAG-ZsGreen1)Jahe

HDRZsGreen
Ai6-HDR2

Gt(ROSA)26Sorem4(CAG-ZsGreen1)Jahe

HDRZsGreen
Rosa26-mT/mG

Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo

NHEJEGTP
Rosa26-Luciferase

Gt(ROSA)26Sortm1(Luc)Kael

NHEJLuciferase
Tlr2

Gt(ROSA)26Sortm12(CAG-Venus*,-TagRFP*)Rkuhn

NHEJ, HDRVenus, RFP

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Mouse Strains Available for Disease Model Testing

Content
Common NameAlleleCondition
∆F

Cftrtm1Kth

Cystic fibrosis
WHC

LdlrHlb301

Familial hypercholesterolemia
Mdx

Dmdmdx

Duchenne muscular dystrophy
rd16

CEP290rd16

Leber congenital amaurosis 10
disheveled hair & ears

LmnaDhe

Laminopathies
spf-ash

Otcspf-ash

Ornithine transcarbamylase deficiency
SOD1-G93A

Tg(SOD1*G93A)1Gur/J

Amyotrophic lateral sclerosis

PAHenu2

PAHenu2

Phenylketonuria