About the Lab

The Van den Veyver laboratory, Department of Obstetrics and Gynecology, Baylor College of Medicine is located at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital

Our research has the following areas of focus:

We study the genetics of X-linked dominant disorders, Aicardi Syndrome and Goltz Syndrome (Focal Dermal Hypoplasia). We recently identified PORCN as the gene mutated in Goltz syndrome.  We have a project investigating genetics of sporadic and recurrent hydatidiform moles. This is an abnormal development of pregnancy with disrupted imprinting. These disorders are an excellent model to investigate genomic imprinting in human placenta.

Another area of research interest in the lab is elucidating the link between prenatal stressors and manifestation of autism spectrum disorder in infants.

Our third project seeks to understand the epigenetic changes that are at the basis of the developmental origin of adult disease (Barker Hypothesis). For this project we feed mice various diets during pregnancy and suckling, and study the long-term effects in the offspring using various molecular approaches.

Study Participation

If you have questions about or are interested in participating in one of our studies, please contact our lab administrative coordinator - Renee Elawar, (832) 824-8156 or relawar@bcm.edu