Jin Wang Lab

Master
Media Component
Jin Wang
Global distribution of GSH probes developed by the Jin Wang group. The GSH probes, including RealThiol (RT) and Mito-RealThiol (Mitro-RT) probes, have been distributed to over 50 institutions worldwide through either MTAs or Kerafast.com.
Heading

Impact of Our GSH Probes

Content

Global distribution of GSH probes developed by our group. The GSH probes, including RealThiol (RT) and Mito-RealThiol (Mito-RT) probes, have been distributed to over 50 institutions worldwide through either material transfer agreements (MTAs) or Kerafast.com. The map is updated on Dec 27, 2018.

Media Component
Targeting SRC-3 shuts down many cancer signaling pathways simultaneously
Heading

Steroid Receptor Coactivator 3 (SRC-3) Small Molecule Inhibitors

Content

We developed a small molecule inhibitor that can inhibitor SRC-3 and impact many cancer signaling pathways simultaneously (PNAS 2016).

Heading

About the Lab

Content

We are a highly interdisciplinary group and interested in developing tools for biological and biomedical studies. Currently, our research is mainly focused in three areas:

  • Developing novel fluorescent probes to quantitatively monitor real-time glutathione dynamics in living cells
  • Developing small molecule inhibitor against coactivators to treat breast cancer
  • Developing antibody drug conjugates as novel cancer therapies