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BCM - Baylor College of Medicine

Giving life to possible

Research

Overview

Home to one of the nation’s largest biomedical research programs, Baylor College of Medicine has a proven track record of success.

The scale of our research enterprise; the exceptional caliber of faculty we attract; and the richness of biomedical research resources within Houston support creativity, innovation, and discovery. Our faculty, whether native Texans or not, embrace the Texas “can do” spirit as well as a strong sense of family. This combination creates a balance between ambitious competitiveness and unwavering loyalty to colleagues. The result is an environment in which faculty mentor each other, support each other, and celebrate each other’s successes.

Baylor is the only stand alone life sciences college ranked among the top 50 colleges and universities for research and development expenditures by BestColleges.com

To learn about ongoing research activities visit our academic departments and multi-disciplinary centers

National Institutes of Health Funding

Reports by the Blue Ridge Institute for Medical Research of funding from the National Institutes of Health are one indicator of the depth and breadth of our research enterprise.

  • $178,214,625 – funding from National Institutes of Health to BCM for 2013
  • No. 19 – BCM’s rank among U.S. medical schools in NIH funding for 2013
  • No. 1 – BCM's rank among Texas medical schools in NIH funding for 2013

Departments Ranked in the top 20 in NIH funding

  • No. 1 Molecular & Human Genetics
  • No. 2 Molecular & Cellular Biology
  • No. 4 Pediatrics
  • No. 7 Neuroscience
  • No. 10 Biochemistry
  • No. 13 Urology
  • No. 13 Neurosurgery
  • No. 14 Physical Medicine & Rehabilitation

Selected Research Achievements

Baylor College of Medicine researchers have been at the forefront of many of the major advances in biomedical sciences over the last century. They:

- Opened the first center for the treatment of polio in the United States

- Developed the first successful implement to straighten the spines of patients with scoliosis

- Pioneered the field of molecular endocrinology with seminal work on steroid hormone action and the discovery of steroid receptor coactivators, master regulatory cells in the body

- Determined the sequences of chromosomes 3, 12 and part of X as part of their role as one of three centers to complete the Human Genome Project

- Led sequencing of many animal genomes, including the mouse, rat, fruit fly, rhesus monkey, honey bee, sea urchin, marmoset, orangutan, and cow

- Discovered the cytoplasmic microtubule complex in eukaryotic cells, a finding that led to use of a new class of cancer drugs including taxol

- Proved using isoniaizid long-term can prevent TB in children with latent infection

- Invented the Dacron graft

- Found that an enterotoxin is responsible for the diarrhea commonly caused in children by rotavirus

- Described the first case of uniparental disomy, in which a child receives both copies of a gene from one parent

- Pioneered gene chip technology that streamlines diagnosis of genetic and chromosomal diseases

- Discovered the gene that causes Rett syndrome, a post natal genetic disorder that affects mainly girls

- Identified new mutations in a cartilage protein that results in a lethal form of the brittle bone disease called osteogenesis imperfect

- Sequenced and annotated the first personalized genome sequence, that of Dr. James Watson, Nobel laureate who described DNA’s double helix

- Developed a translational technique to train T-cells to kill cancers associated with Epstein-Barr virus

- Pioneered the study of eating disorders