Biomarker Variability and Predictive Value in Dyspnea (H-37226)

Background: Dyspnea is a common complaint in the emergency department (ED). An accurate and rapid diagnosis of these dyspneic patients is a challenging issue. Natriuretic peptides (NPs) are useful diagnostic tools to differentiate between cardiac and pulmonary etiology of dyspnea and are also predictors of mortality.

Data on B-type natriuretic peptide are incomplete, since values and outcomes are reportedly different among 4 regions including North America, South America, Western and Eastern Europe. Nonetheless in real clinical setting, we use NPs as diagnostic tool and to predict the prognosis.

Purpose: Evaluate regional differences in biomarker values and in clinical outcomes in dyspneic patients

Project status: currently enrolling

Coordinator Role: screen, consent, enroll and collect data.

Open to students: Yes