Iron Status and Brain Structure and Function (H-46673 )
Iron Deficiency is the most common micronutrient deficiency in the world, in children and women capable of having children. Iron deficiency can be associated with problems with attention, learning, and even depression and anxiety. In this study, we would like to learn how the amount of iron children and teens have in their body affects the amount of iron they have in their brain and whether this affects brain development, thinking, and emotions. Our goal is to recruit 3 groups of kids between the ages of 10 and 17 years old: 1) Some with depression, but who are not taking any psychiatric medications, 2) some having been taking risperidone for at least six months, and 3) some who have never experienced a psychiatric illness. This study involves one clinic visit, collection of blood, saliva, urine, and stool samples, a brief physical exam, questionnaires for both participants and the parents to complete, a brain scan (MRI), and completing a concentration and memory game. We provide compensation between $20 and $120 in addition to reimbursement for transportation expenses, a copy of the brain scan, and a meal.