Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Adolescents (H-47575)
Latino adolescents (14-16 years) are disproportionately impacted by obesity compared to the general population (25.8% vs 18.5%) and are at an increased risk for obesity-related metabolic diseases like type 2 diabetes and cardiovascular diseases. These disparities are due in part to unhealthy lifestyle behaviors like excessive time spent in sedentary behaviors (i.e. sitting, screen time). Youth with obesity spend an estimated 65-75% of their day in sedentary pursuits. In adults, sedentary behaviors are associated with adverse metabolic profiles.
However, evidence on the association between objective sedentary behaviors and cardiometabolic disease risk factors in youth remains inconclusive. This is due in part to the lack of controlled studies with rigorous measures of sedentary behaviors or metabolic outcomes.
To address these gaps, the goal of this study is to utilize whole-room calorimetry to examine the effects of an acute bout of sedentary behaviors on cardiometabolic outcomes (glucose, insulin, lipids, arterial stiffness) and energy metabolism (energy expenditure, substrate utilization) in Latino adolescents (12-16 years old) with obesity (BMI% ≥95th) as compared to non-Latino white adolescents (12-16 years old) with obesity.