Blair Benham-Pyle, Ph.D.
Discovering cellular and molecular adaptations for whole body regeneration and resistance to aging and disease using planaria
Alison A. Bertuch, M.D., Ph.D.
Focusing on the molecular genetics of the telomere biology disorders and ribosomopathies
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Weiwei Dang, Ph.D.
Studying epigenetic regulation of aging
Herman A. Dierick, M.D.
Dissecting the genetic and neurobiological mechanisms of aggression using flies as a model system
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Kyle P. Eagen, Ph.D.
Determining how DNA is folded inside cells
Graham Erwin, Ph.D.
Investigating the functional role of repetitive DNA with a focus on translating these discoveries for human health.
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
Margaret A. Goodell, Ph.D.
Investigating genetic regulation of stem cells and hematopoiesis
Christophe Herman, Ph.D.
Transcription errors in epigenetic and genome stability
H. Courtney Hodges, Ph.D.
Using epigenomics and chemical biology to reveal new mechanisms related to chromatin, transcription factors, and gene regulation
Grzegorz Ira, Ph.D.
Investigating the mechanisms of DNA recombination and genome instability
William R. Lagor, Ph.D.
Studying lipid and lipoprotein metabolism, and developing new approaches for gene therapy and gene editing
James F. Martin, M.D., Ph.D.
Understanding tissue regeneration in humans
David L. Nelson, Ph.D.
Studying human disorders caused by repeat sequence expansions using humans, mice and flies
Sharon E. Plon, M.D., Ph.D.
Expanding knowledge on the basis of genetic predisposition to childhood cancer
Susan M. Rosenberg, Ph.D.
Investigating molecular mechanisms of genome instability and evolution of cancers and infectious diseases
Pawel Stankiewicz, M.D., Ph.D.
Studying the genetics and genomics of lung development in humans and the role of noncoding elements in lethal lung developmental disorders in neonates
Eric Van Nostrand, Ph.D.
Using genomics, molecular biology, and bioinformatics to study how RNA binding proteins control a variety of RNA processing steps
Dimitrios Laurin Wagner, M.D., Ph.D.
Focuses on Genome Editing and Immunology to develop gene therapies for cancer, autoimmune diseases, and genetic disorders
Cheryl Walker, Ph.D.
Studying how our early-life environment shapes our epigenome to determine health and drive disease
Tao Wu, Ph.D.
Studying the epigenetic mechanisms underpinning cell fate transition and plasticity in human diseases
Qian Zhu, Ph.D.
Applying single-cell, spatial, and imaging bioinformatics to the breast tumor microenvironment to uncover the genomic, epigenomic, cellular, and multicellular factors influencing patient survival and treatment outcomes.
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases
Benjamin R. Arenkiel, Ph.D.
Investigating the developmental and genetic mechanisms that govern the formation and function of neural circuits
Hugo J. Bellen, D.V.M., Ph.D.
Studying rare and common human genetic disease using flies
Blair Benham-Pyle, Ph.D.
Discovering cellular and molecular adaptations for whole body regeneration and resistance to aging and disease using planaria
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Hsiao-Tuan Chao, M.D., Ph.D.
Integrating cross-species approaches in humans to uncover the genetic etiologies of neurodevelopmental disorders, fruit flies to elucidate the molecular pathways, and mice to explore the cascade of events in the mammalian brain
Chonghui Cheng, M.D., Ph.D.
Investigating breast cancer metastasis and circulating tumor cells regulated by RNA processes
Thomas A. Cooper, M.D.
Investigating the pathogenic mechanisms of myotonic dystrophy type 1, focusing on developmentally regulated RNA processing
Vishnu Cuddapah, M.D., Ph.D.
Investigating interactions between sleep, circadian rhythms, and neurodevelopmental disorders from flies to people.
Weiwei Dang, Ph.D.
Studying epigenetic regulation of aging
Ryan S Dhindsa, M.D., Ph.D.
Using population-level genetics, multi-omics, and stem cell models to identify targeted therapies, with an emphasis on neurological disease.
Herman A. Dierick, M.D.
Dissecting the genetic and neurobiological mechanisms of aggression using flies as a model system
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Kyle P. Eagen, Ph.D.
Determining how DNA is folded inside cells
Gloria V. Echeverria, Ph.D.
Studying the metabolic evolution of breast cancer
Graham Erwin, Ph.D.
Investigating the functional role of repetitive DNA with a focus on translating these discoveries for human health.
Benjamin J. Frankfort, M.D., Ph.D.
Dr. Frankfort’s lab studies the earliest changes that occur in the retina of mice with glaucoma and uses this information to better understand normal and disease-altered mechanisms of neuronal injury, resistance, and recovery.
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
Margaret A. Goodell, Ph.D.
Investigating genetic regulation of stem cells and hematopoiesis
Sean M. Hartig, Ph.D.
Exploring fundamentals of metabolism and energy balance in obesity and diabetes
Jason D. Heaney, Ph.D.
Using mouse genetics, genomics and genome editing technologies to catalog gene function and contribution to human disease
Christophe Herman, Ph.D.
Transcription errors in epigenetic and genome stability
H. Courtney Hodges, Ph.D.
Using epigenomics and chemical biology to reveal new mechanisms related to chromatin, transcription factors, and gene regulation
Benny A. Kaipparettu, Ph.D.
Investigating mitochondrial metabolism in cancer
William R. Lagor, Ph.D.
Studying lipid and lipoprotein metabolism, and developing new approaches for gene therapy and gene editing
Brendan Lee, M.D., Ph.D.
Investigating human and mouse genetics of skeletal and metabolic diseases, developing gene therapy, and studying undiagnosed diseases
Pengfei Liu, Ph.D.
We are interested in translating new technologies to improve the diagnosis and therapy of Mendelian disorders.
Zhandong Liu, Ph.D.
Developing machine learning and AI tools for biomedical datasets
James F. Martin, M.D., Ph.D.
Understanding tissue regeneration in humans
Tamer M A Mohamed, Pharm.D., Ph.D.
Understanding the genetic modulation of the cell cycle in cardiomyocytes and developing bioengineering approaches for drug testing in human heart tissues
Ronald J. Parchem, Ph.D.
Investigating stem cell function in development and disease
Ross A. Poché, Ph.D.
Identifying the cellular and molecular mechanisms regulating mammalian development and regeneration
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Buck Samuel, Ph.D.
Investigating the genetics of microbiome impact on host metabolism and physiology
Gad Shaulsky, Ph.D.
Study the molecular genetics of allorecognition and its relationship to development and sociality
Joshua M. Shulman, M.D., Ph.D.
Investigating the genomic mechanisms of Alzheimer's and Parkinson's disease
Richard N. Sifers, Ph.D.
Investigating altered proteostasis in inherited disease and cancer
Pawel Stankiewicz, M.D., Ph.D.
Studying the genetics and genomics of lung development in humans and the role of noncoding elements in lethal lung developmental disorders in neonates
Zheng Sun, Ph.D.
Investigating the circadian clock and epigenome in metabolism and neurocognition
Nicholas Tran, Ph.D.
Investigating mechanisms of neuroprotection and axon regeneration for neurodegenerative diseases that cause blindness
Eric Van Nostrand, Ph.D.
Using genomics, molecular biology, and bioinformatics to study how RNA binding proteins control a variety of RNA processing steps
Dimitrios Laurin Wagner, M.D., Ph.D.
Focuses on Genome Editing and Immunology to develop gene therapies for cancer, autoimmune diseases, and genetic disorders
Xander Wehrens, M.D., Ph.D.
Focusing on the molecular basis of inherited arrhythmia syndromes as well as other more complex, multifactorial cardiac diseases.
Jeremy E. Wilusz, Ph.D.
Revealing how noncoding RNAs are generated, regulated, and function
Tao Wu, Ph.D.
Studying the epigenetic mechanisms underpinning cell fate transition and plasticity in human diseases
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Qian Zhu, Ph.D.
Applying single-cell, spatial, and imaging bioinformatics to the breast tumor microenvironment to uncover the genomic, epigenomic, cellular, and multicellular factors influencing patient survival and treatment outcomes.
Huda Y. Zoghbi, M.D.
Using genetic and biochemical tools to understand disease neurobiology
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases
Blair Benham-Pyle, Ph.D.
Discovering cellular and molecular adaptations for whole body regeneration and resistance to aging and disease using planaria
Chonghui Cheng, M.D., Ph.D.
Investigating breast cancer metastasis and circulating tumor cells regulated by RNA processes
Weiwei Dang, Ph.D.
Studying epigenetic regulation of aging
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Kyle P. Eagen, Ph.D.
Determining how DNA is folded inside cells
Gloria V. Echeverria, Ph.D.
Studying the metabolic evolution of breast cancer
Graham Erwin, Ph.D.
Investigating the functional role of repetitive DNA with a focus on translating these discoveries for human health.
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
Margaret A. Goodell, Ph.D.
Investigating genetic regulation of stem cells and hematopoiesis
Christophe Herman, Ph.D.
Transcription errors in epigenetic and genome stability
H. Courtney Hodges, Ph.D.
Using epigenomics and chemical biology to reveal new mechanisms related to chromatin, transcription factors, and gene regulation
Zhandong Liu, Ph.D.
Developing machine learning and AI tools for biomedical datasets
James F. Martin, M.D., Ph.D.
Understanding tissue regeneration in humans
Tamer M A Mohamed, Pharm.D., Ph.D.
Understanding the genetic modulation of the cell cycle in cardiomyocytes and developing bioengineering approaches for drug testing in human heart tissues
Richard N. Sifers, Ph.D.
Investigating altered proteostasis in inherited disease and cancer
Zheng Sun, Ph.D.
Investigating the circadian clock and epigenome in metabolism and neurocognition
Nicholas Tran, Ph.D.
Investigating mechanisms of neuroprotection and axon regeneration for neurodegenerative diseases that cause blindness
Ignatia B. Van den Veyver, M.D.
Investigating the genetics and epigenetics of reproductive and developmental disorders, and prenatal genetic diagnosis
Cheryl Walker, Ph.D.
Studying how our early-life environment shapes our epigenome to determine health and drive disease
Tao Wu, Ph.D.
Studying the epigenetic mechanisms underpinning cell fate transition and plasticity in human diseases
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Qian Zhu, Ph.D.
Applying single-cell, spatial, and imaging bioinformatics to the breast tumor microenvironment to uncover the genomic, epigenomic, cellular, and multicellular factors influencing patient survival and treatment outcomes.
Huda Y. Zoghbi, M.D.
Using genetic and biochemical tools to understand disease neurobiology
Benjamin R. Arenkiel, Ph.D.
Investigating the developmental and genetic mechanisms that govern the formation and function of neural circuits
Elizabeth Atkinson, Ph.D.
Developing statistical and computational methods to enhance the accuracy and generalizability of genetic research across globally representative populations
Blair Benham-Pyle, Ph.D.
Discovering cellular and molecular adaptations for whole body regeneration and resistance to aging and disease using planaria
Steven Boeynaems, Ph.D.
Studying protein condensation and aggregation in health and disease
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Chonghui Cheng, M.D., Ph.D.
Investigating breast cancer metastasis and circulating tumor cells regulated by RNA processes
Thomas A. Cooper, M.D.
Investigating the pathogenic mechanisms of myotonic dystrophy type 1, focusing on developmentally regulated RNA processing
Edward C. Cooper, M.D., Ph.D.
Studying the roles of ion channel genes in health and disease, especially the roles of voltage-gated channels in neurodevelopmental disorders
Ryan S Dhindsa, M.D., Ph.D.
Using population-level genetics, multi-omics, and stem cell models to identify targeted therapies, with an emphasis on neurological disease.
Herman A. Dierick, M.D.
Dissecting the genetic and neurobiological mechanisms of aggression using flies as a model system
Florent Elefteriou, Ph.D.
Focusing on understanding how bones form, grow, age and repair
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
Jason D. Heaney, Ph.D.
Using mouse genetics, genomics and genome editing technologies to catalog gene function and contribution to human disease
Christophe Herman, Ph.D.
Transcription errors in epigenetic and genome stability
Hamed Jafar-Nejad, M.D.
Using fly and mouse models to understand the contribution of glycosylation to embryonic development and the pathophysiology of specific human disease, with an eye on establishing novel therapeutic approaches
Brendan Lee, M.D., Ph.D.
Investigating human and mouse genetics of skeletal and metabolic diseases, developing gene therapy, and studying undiagnosed diseases
Zhandong Liu, Ph.D.
Developing machine learning and AI tools for biomedical datasets
James F. Martin, M.D., Ph.D.
Understanding tissue regeneration in humans
Tamer M A Mohamed, Pharm.D., Ph.D.
Understanding the genetic modulation of the cell cycle in cardiomyocytes and developing bioengineering approaches for drug testing in human heart tissues
Ronald J. Parchem, Ph.D.
Investigating stem cell function in development and disease
Ross A. Poché, Ph.D.
Identifying the cellular and molecular mechanisms regulating mammalian development and regeneration
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Jeffrey Rogers, Ph.D.
Focusing on two aspects of primate genetics: fundamental studies of basic primate genomics and the discovery of new primate models of human genetic disease
Susan M. Rosenberg, Ph.D.
Investigating molecular mechanisms of genome instability and evolution of cancers and infectious diseases
Buck Samuel, Ph.D.
Investigating the genetics of microbiome impact on host metabolism and physiology
Daryl A. Scott, M.D., Ph.D.
Identifying the genes that cause common, life-threatening birth defects and to determine the molecular mechanisms by which they function
Gad Shaulsky, Ph.D.
Study the molecular genetics of allorecognition and its relationship to development and sociality
Pawel Stankiewicz, M.D., Ph.D.
Studying the genetics and genomics of lung development in humans and the role of noncoding elements in lethal lung developmental disorders in neonates
Nicholas Tran, Ph.D.
Investigating mechanisms of neuroprotection and axon regeneration for neurodegenerative diseases that cause blindness
Ignatia B. Van den Veyver, M.D.
Investigating the genetics and epigenetics of reproductive and developmental disorders, and prenatal genetic diagnosis
Shinya Yamamoto, D.V.M., Ph.D.
Studying diverse medically relevant questions using the fruit fly, primarily focusing on the nervous system and neurological disorders
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Qian Zhu, Ph.D.
Applying single-cell, spatial, and imaging bioinformatics to the breast tumor microenvironment to uncover the genomic, epigenomic, cellular, and multicellular factors influencing patient survival and treatment outcomes.
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases
Hugo J. Bellen, D.V.M., Ph.D.
Studying rare and common human genetic disease using flies
Lindsay Burrage, M.D., Ph.D.
Investigating rare metabolic disorders as models for understanding basic biological processes that impact more common diseases
Vishnu Cuddapah, M.D., Ph.D.
Investigating interactions between sleep, circadian rhythms, and neurodevelopmental disorders from flies to people.
Gloria V. Echeverria, Ph.D.
Studying the metabolic evolution of breast cancer
Sean M. Hartig, Ph.D.
Exploring fundamentals of metabolism and energy balance in obesity and diabetes
Hamed Jafar-Nejad, M.D.
Using fly and mouse models to understand the contribution of glycosylation to embryonic development and the pathophysiology of specific human disease, with an eye on establishing novel therapeutic approaches
Benny A. Kaipparettu, Ph.D.
Investigating mitochondrial metabolism in cancer
William R. Lagor, Ph.D.
Studying lipid and lipoprotein metabolism, and developing new approaches for gene therapy and gene editing
Brendan Lee, M.D., Ph.D.
Investigating human and mouse genetics of skeletal and metabolic diseases, developing gene therapy, and studying undiagnosed diseases
David L. Nelson, Ph.D.
Studying human disorders caused by repeat sequence expansions using humans, mice and flies
Ronald J. Parchem, Ph.D.
Investigating stem cell function in development and disease
Ross A. Poché, Ph.D.
Identifying the cellular and molecular mechanisms regulating mammalian development and regeneration
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Buck Samuel, Ph.D.
Investigating the genetics of microbiome impact on host metabolism and physiology
Joshua M. Shulman, M.D., Ph.D.
Investigating the genomic mechanisms of Alzheimer's and Parkinson's disease
Shubham Singh, Ph.D.
Investigating molecular mechanisms of metabolic disorders and studying how genetic variation in metabolism leads to neurodegenerative diseases.
Zheng Sun, Ph.D.
Investigating the circadian clock and epigenome in metabolism and neurocognition
Michael F. Wangler, M.D.
Investigating the molecular basis of Mendelian disorders leveraging fly and clinical studies
Xander Wehrens, M.D., Ph.D.
Focusing on the molecular basis of inherited arrhythmia syndromes as well as other more complex, multifactorial cardiac diseases.
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Hugo J. Bellen, D.V.M., Ph.D.
Studying rare and common human genetic disease using flies
Alison A. Bertuch, M.D., Ph.D.
Focusing on the molecular genetics of the telomere biology disorders and ribosomopathies
Steven Boeynaems, Ph.D.
Studying protein condensation and aggregation in health and disease
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Lindsay Burrage, M.D., Ph.D.
Investigating rare metabolic disorders as models for understanding basic biological processes that impact more common diseases
Hsiao-Tuan Chao, M.D., Ph.D.
Integrating cross-species approaches in humans to uncover the genetic etiologies of neurodevelopmental disorders, fruit flies to elucidate the molecular pathways, and mice to explore the cascade of events in the mammalian brain
Chonghui Cheng, M.D., Ph.D.
Investigating breast cancer metastasis and circulating tumor cells regulated by RNA processes
Edward C. Cooper, M.D., Ph.D.
Studying the roles of ion channel genes in health and disease, especially the roles of voltage-gated channels in neurodevelopmental disorders
Thomas A. Cooper, M.D.
Investigating the pathogenic mechanisms of myotonic dystrophy type 1, focusing on developmentally regulated RNA processing
Vishnu Cuddapah, M.D., Ph.D.
Investigating interactions between sleep, circadian rhythms, and neurodevelopmental disorders from flies to people.
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Kyle P. Eagen, Ph.D.
Determining how DNA is folded inside cells
Florent Elefteriou, Ph.D.
Focusing on understanding how bones form, grow, age and repair
Graham Erwin, Ph.D.
Investigating the functional role of repetitive DNA with a focus on translating these discoveries for human health.
Richard H. Finnell, Ph.D.
Preventing preventable birth defects
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
Margaret A. Goodell, Ph.D.
Investigating genetic regulation of stem cells and hematopoiesis
Sean M. Hartig, Ph.D.
Exploring fundamentals of metabolism and energy balance in obesity and diabetes
Jason D. Heaney, Ph.D.
Using mouse genetics, genomics and genome editing technologies to catalog gene function and contribution to human disease
H. Courtney Hodges, Ph.D.
Using epigenomics and chemical biology to reveal new mechanisms related to chromatin, transcription factors, and gene regulation
Hamed Jafar-Nejad, M.D.
Using fly and mouse models to understand the contribution of glycosylation to embryonic development and the pathophysiology of specific human disease, with an eye on establishing novel therapeutic approaches
Benny A. Kaipparettu, Ph.D.
Investigating mitochondrial metabolism in cancer
William R. Lagor, Ph.D.
Studying lipid and lipoprotein metabolism, and developing new approaches for gene therapy and gene editing
Brendan Lee, M.D., Ph.D.
Investigating human and mouse genetics of skeletal and metabolic diseases, developing gene therapy, and studying undiagnosed diseases
Pengfei Liu, Ph.D.
We are interested in translating new technologies to improve the diagnosis and therapy of Mendelian disorders.
Ronit Marom, M.D., Ph.D.
Studying inherited bone fragility disorders associated with protein trafficking defects using in vitro and in vivo models.
James F. Martin, M.D., Ph.D.
Understanding tissue regeneration in humans
David L. Nelson, Ph.D.
Studying human disorders caused by repeat sequence expansions using humans, mice and flies
Ronald J. Parchem, Ph.D.
Investigating stem cell function in development and disease
D. Williams Parsons, M.D., Ph.D.
Focusing on the clinical application of genetics and genomics to the improve the care of childhood cancer patients and their families
Sharon E. Plon, M.D., Ph.D.
Expanding knowledge on the basis of genetic predisposition to childhood cancer
Ross A. Poché, Ph.D.
Identifying the cellular and molecular mechanisms regulating mammalian development and regeneration
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Susan M. Rosenberg, Ph.D.
Investigating molecular mechanisms of genome instability and evolution of cancers and infectious diseases
Buck Samuel, Ph.D.
Investigating the genetics of microbiome impact on host metabolism and physiology
Daryl A. Scott, M.D., Ph.D.
Identifying the genes that cause common, life-threatening birth defects and to determine the molecular mechanisms by which they function
Joshua M. Shulman, M.D., Ph.D.
Investigating the genomic mechanisms of Alzheimer's and Parkinson's disease
Richard N. Sifers, Ph.D.
Investigating altered proteostasis in inherited disease and cancer
Shubham Singh, Ph.D.
Investigating molecular mechanisms of metabolic disorders and studying how genetic variation in metabolism leads to neurodegenerative diseases.
Pawel Stankiewicz, M.D., Ph.D.
Studying the genetics and genomics of lung development in humans and the role of noncoding elements in lethal lung developmental disorders in neonates
Zheng Sun, Ph.D.
Investigating the circadian clock and epigenome in metabolism and neurocognition
Nicholas Tran, Ph.D.
Investigating mechanisms of neuroprotection and axon regeneration for neurodegenerative diseases that cause blindness
Ignatia B. Van den Veyver, M.D.
Investigating the genetics and epigenetics of reproductive and developmental disorders, and prenatal genetic diagnosis
Cheryl Walker, Ph.D.
Studying how our early-life environment shapes our epigenome to determine health and drive disease
Michael F. Wangler, M.D.
Investigating the molecular basis of Mendelian disorders leveraging fly and clinical studies
Xander Wehrens, M.D., Ph.D.
Focusing on the molecular basis of inherited arrhythmia syndromes as well as other more complex, multifactorial cardiac diseases.
Tao Wu, Ph.D.
Studying the epigenetic mechanisms underpinning cell fate transition and plasticity in human diseases
Mingshan Xue, Ph.D.
Elucidating the synaptic mechanisms of neural circuits in the mammalian brain and harness this knowledge to understand the pathogeneses and develop therapies for neurodevelopmental disorders
Shinya Yamamoto, D.V.M., Ph.D.
Studying diverse medically relevant questions using the fruit fly, primarily focusing on the nervous system and neurological disorders
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Hui Zheng, Ph.D.
Investigating lysosome signaling and immune regulation in Alzheimer's disease
Huda Y. Zoghbi, M.D.
Using genetic and biochemical tools to understand disease neurobiology
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases
Benjamin R. Arenkiel, Ph.D.
Investigating the developmental and genetic mechanisms that govern the formation and function of neural circuits
Hugo J. Bellen, D.V.M., Ph.D.
Studying rare and common human genetic disease using flies
Steven Boeynaems, Ph.D.
Studying protein condensation and aggregation in health and disease
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Hsiao-Tuan Chao, M.D., Ph.D.
Integrating cross-species approaches in humans to uncover the genetic etiologies of neurodevelopmental disorders, fruit flies to elucidate the molecular pathways, and mice to explore the cascade of events in the mammalian brain
Edward C. Cooper, M.D., Ph.D.
Studying the roles of ion channel genes in health and disease, especially the roles of voltage-gated channels in neurodevelopmental disorders
Vishnu Cuddapah, M.D., Ph.D.
Investigating interactions between sleep, circadian rhythms, and neurodevelopmental disorders from flies to people.
Herman A. Dierick, M.D.
Dissecting the genetic and neurobiological mechanisms of aggression using flies as a model system
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Benjamin J. Frankfort, M.D., Ph.D.
Dr. Frankfort’s lab studies the earliest changes that occur in the retina of mice with glaucoma and uses this information to better understand normal and disease-altered mechanisms of neuronal injury, resistance, and recovery.
Hongjie Li, Ph.D.
Performing single-cell analysis to understand aging
Pengfei Liu, Ph.D.
We are interested in translating new technologies to improve the diagnosis and therapy of Mendelian disorders.
David L. Nelson, Ph.D.
Studying human disorders caused by repeat sequence expansions using humans, mice and flies
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Jeffrey Rogers, Ph.D.
Focusing on two aspects of primate genetics: fundamental studies of basic primate genomics and the discovery of new primate models of human genetic disease
Susan M. Rosenberg, Ph.D.
Investigating molecular mechanisms of genome instability and evolution of cancers and infectious diseases
Buck Samuel, Ph.D.
Investigating the genetics of microbiome impact on host metabolism and physiology
Joshua M. Shulman, M.D., Ph.D.
Investigating the genomic mechanisms of Alzheimer's and Parkinson's disease
Shubham Singh, Ph.D.
Investigating molecular mechanisms of metabolic disorders and studying how genetic variation in metabolism leads to neurodegenerative diseases.
Zheng Sun, Ph.D.
Investigating the circadian clock and epigenome in metabolism and neurocognition
Nicholas Tran, Ph.D.
Investigating mechanisms of neuroprotection and axon regeneration for neurodegenerative diseases that cause blindness
Xander Wehrens, M.D., Ph.D.
Focusing on the molecular basis of inherited arrhythmia syndromes as well as other more complex, multifactorial cardiac diseases.
Mingshan Xue, Ph.D.
Elucidating the synaptic mechanisms of neural circuits in the mammalian brain and harness this knowledge to understand the pathogeneses and develop therapies for neurodevelopmental disorders
Shinya Yamamoto, D.V.M., Ph.D.
Studying diverse medically relevant questions using the fruit fly, primarily focusing on the nervous system and neurological disorders
Lilei Zhang, M.D., Ph.D.
Studying heart failure and inherited heart diseases
Hui Zheng, Ph.D.
Investigating lysosome signaling and immune regulation in Alzheimer's disease
Huda Y. Zoghbi, M.D.
Using genetic and biochemical tools to understand disease neurobiology
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases
Elizabeth Atkinson, Ph.D.
Developing statistical and computational methods to enhance the accuracy and generalizability of genetic research across globally representative populations
Juan Botas, Ph.D.
Integrating in silico and high-throughput experimental approaches to investigate brain disorders
Chonghui Cheng, M.D., Ph.D.
Investigating breast cancer metastasis and circulating tumor cells regulated by RNA processes
Chao Cheng, Ph.D.
Integrating multi-omics data for reveal human disease mechanism with emphasis on cancer
Ryan S Dhindsa, M.D., Ph.D.
Using population-level genetics, multi-omics, and stem cell models to identify targeted therapies, with an emphasis on neurological disease.
Vishnu Dileep, Ph.D.
Studying the genomic and epigenomic drivers of brain aging and neurodegeneration
Kyle P. Eagen, Ph.D.
Determining how DNA is folded inside cells
Richard A. Gibbs, Ph.D.
Investigating genomics, genetics and genome biology
H. Courtney Hodges, Ph.D.
Using epigenomics and chemical biology to reveal new mechanisms related to chromatin, transcription factors, and gene regulation
Benny A. Kaipparettu, Ph.D.
Investigating mitochondrial metabolism in cancer
Hongjie Li, Ph.D.
Performing single-cell analysis to understand aging
Pengfei Liu, Ph.D.
We are interested in translating new technologies to improve the diagnosis and therapy of Mendelian disorders.
Zhandong Liu, Ph.D.
Developing machine learning and AI tools for biomedical datasets
D. Williams Parsons, M.D., Ph.D.
Focusing on the clinical application of genetics and genomics to the improve the care of childhood cancer patients and their families
Russell S. Ray, Ph.D.
Understanding the neural circuits that underly human behavior and physiology and their roles in disease.
Susan M. Rosenberg, Ph.D.
Investigating molecular mechanisms of genome instability and evolution of cancers and infectious diseases
Gad Shaulsky, Ph.D.
Study the molecular genetics of allorecognition and its relationship to development and sociality
Joshua M. Shulman, M.D., Ph.D.
Investigating the genomic mechanisms of Alzheimer's and Parkinson's disease
Shubham Singh, Ph.D.
Investigating molecular mechanisms of metabolic disorders and studying how genetic variation in metabolism leads to neurodegenerative diseases.
Eric Van Nostrand, Ph.D.
Using genomics, molecular biology, and bioinformatics to study how RNA binding proteins control a variety of RNA processing steps
Shinya Yamamoto, D.V.M., Ph.D.
Studying diverse medically relevant questions using the fruit fly, primarily focusing on the nervous system and neurological disorders
Qian Zhu, Ph.D.
Applying single-cell, spatial, and imaging bioinformatics to the breast tumor microenvironment to uncover the genomic, epigenomic, cellular, and multicellular factors influencing patient survival and treatment outcomes.
Anthony Zoghbi, M.D.
Understanding the genomic basis of risk and treatment response across neuropsychiatric disorders using advanced computational and bioinformatic techniques
Chenghang (Chuck) Zong, Ph.D.
Developing novel single cell sequencing based methods for profiling cancer evolution and heterogeneity, understanding complex human diseases