Research: Development of a Vertical Flow paper-based Platform (VFP) for Monitoring Health Outcomes in Inflight Condition
Institution: University of Arizona College of Medicine, Phoenix, Ariz.
Start Date: May 1, 2018
End Date: April 30, 2019
TRISH Synergy Project: Novel Microfluidic Biomarker Detection Platforms to Monitor In Vivo Effects of Solar Particle Events and Galactic Cosmic Rays Radiation, Using Mice with Human Hematopoietic Systems
Study Type: Ground Study
NASA Risk Addressed: Medical
Problem Addressed: This project will design and characterize a novel Vertical Flow Paper-based Platform (VFP) built within a miniaturized “syringe-like” cartridge that will perform multiplexed detection of bio-agents and up to hundreds of biomarkers in small or large volumes of bodily fluids suitable for diagnosis in long space travel condition.
Major Aim of Project: This project will study bacterial agents (e.g., gut bacteria or other environmental exposure on the International Space Station-ISS), and also nucleic acid detection in order to develop a hybrid platform able to multiplex different types of biomarkers for enabling the diagnosis of multiple conditions.