Viruses infect and replicate in all types of life forms, impacting health and disease in a myriad of ways.  For viruses to successfully replicate, they must utilize host cell factors and processes as well as counteract host innate and adaptive immune responses. Our faculty and trainees in virology investigate different aspects of DNA and RNA virus replication in order to understand how viruses modulate and exploit the host environment to favor their own expression, assembly and infectivity, and to define the critical host responses that control infection.  Basic knowledge of viral and host factors regulating viral replication is used to inform prevention and therapeutic approaches.

Research is supported by the Advanced Technology Cores, Alkek Center for Metagenomics and Microbiome Research, the Center for Drug Discovery, the Dan L Duncan Comprehensive Cancer Center, the Texas Medical Center Digestive Disease Center and the Vaccine Research Center.

Profiles of Faculty Working on Mechanisms of Viral Replication

Margaret Ellen Conner, Ph.D.

Associate Professor

Phone

  • (713) 798-3590

Pathogenesis of and immunity to enteric pathogens

Mary K. Estes, Ph.D.

Distinguished Service Professor

Phone

  • (713) 798-3585

Human mini-gut cultures to understand gastrointestinal virus-host interactions and mechanisms of pathogenesis and immunity

Brian Edward Gilbert, Ph.D.

Associate Professor

Phone

  • (713) 798-4022

Aerosolized drugs for pulmonary diseases

Joseph Michael Hyser, Ph.D.

Assistant Professor

Phone

  • (713) 798-4514

Enteric Virus Calcium Channel Blockers; Exploitation of Host Calcium Signaling Pathways by Microbes…

Jason Thomas Kimata, PH.D.

Associate Professor

Phone

  • (713) 798-4536

HIV Replication, Pathogenesis, and Cure

Paul Dalling Ling, Ph.D.

Associate Professor

Phone

  • (713) 798-8474

Elephant Endotheliotropic Herpesvirus (EEHV); Gammaherpesvirus pathogenesis

Richard E. Lloyd, Ph.D.

Professor

Phone

  • (713) 798-8993

Stress granule dynamics and innate immune activation; Enterovirus host interactions; Role of enterovirus persistent infections in type 1 diabetes

Susan Jean Marriott, Ph.D.

Professor

Phone

  • (713) 798-4440

Viral transformation and transcription control

Pedro A. Piedra, M.D.

Professor

Phone

  • (713) 798-5240

Reduction of respiratory virus illness burden in infants

B V Venkatar Prasad, Ph.D.

Professor

Phone

  • (713) 798-5686

Protein Structure-Function and Protein Folding; Virology, biochemistry, immunology and cell biology of viral and microbial pathogen…

Robert Franklin Ramig, Ph.D.

Professor

Phone

  • (713) 798-4830

Phage Therapy for Human Infections; Genetics of viral replication and pathogenesis

Andrew Patrick Rice, Ph.D.

Professor

Phone

  • (713) 798-5774

Viral gene expression

Rebecca Rico-Hesse, Ph.D., M.P.H.

Professor

Phone

  • (713) 798-3010

Pathogenesis of mosquito-transmitted viruses

Betty L. Slagle, Ph.D.

Associate Professor

Phone

  • (713) 798-3006

Pathogenesis of viral hepatitis

Masataka Suzuki, Ph.D.

Assistant Professor

Phone

  • (832) 824-4673

The application of helper-dependent adenoviral vectors (HDAds) to cancer immunotherapy…