Department of Pathology & Immunology

Curriculum

Master
Heading

Core Curriculum

Terms

Item Term
Molecular Oncology and Cancer Genomics

Item Definition

Fellows are trained to review, interpret and assist in the sign-out of both traditional molecular assays (real-time quantitative PCR, Sanger sequencing, FISH) as well as clinical genomic tests including next-generation sequencing (NGS)-based testing such as whole-exome sequencing, targeted DNA sequencing panels, targeted RNA sequencing panels, cytogenomic SNP arrays etc. Fellows learn to interpret test results in both solid tumors and hematological malignancies in both pediatric and adult populations at Texas Children's Hospital and MD Anderson Cancer Center.

Item Term
Genetics of Inherited Disorders

Item Definition

Fellows receive training at the world-renowned Baylor Genetics laboratories in the principles of genetic testing that covers more than a hundred Mendelian disorders using Sanger sequencing, as well as MALDI-TOF mass spectrometry, and NGS-based clinical diagnostic testing such as whole exome sequencing and targeted DNA panels.

Item Term
Molecular Microbiology

Item Definition

Training covers principles of molecular testing covering all aspects of infectious diseases, including viral load monitoring by PCR, viral genotyping for resistance mutations, bacterial identification by pyrosequencing, etc.

Item Term
Molecular Neuropathology

Item Definition

This is a unique module offered by the fellowship program where residents are exposed to the principles of molecular testing in benign and malignant neurological and musculoskeletal disorders.

Content
Core Curriculum: Training Modules

Training Module

Primary Location(s)

Director

Major Focus

Select Technologies

Molecular Oncology & Cancer Genomics

 

Dolores Lopez-Terrada, M.D., Ph.D.

Pediatric Cancer and Sarcoma Diagnostics

FISH, Real-time PCR, Single-gene sequencing.

 

 

Angshumoy Roy, M.D., Ph.D.

Pediatric cancer genomics

Targeted DNA and RNA NGS panels, tumor whole-exome sequencing, transcriptome sequencing

 

Baylor Genetics Laboratory

Brian Merritt, M.D.

Cancer Diagnostics

Sanger sequencing, Cytogenomic arrays, NGS-based targeted panels (Ion Torrent PGM and MiSeq)

 

Molecular Diagnostics Laboratory at MD Anderson Cancer Center

Raja Luthra, Ph.D.

Cancer Diagnostics

Sanger sequencing, Fragment analysis, Sequenom mass spectrometry, NGS

Inherited Disorders

Baylor Genetics Laboratory

Jennifer Scull, Ph.D.

Genetic Testing

Sanger sequencing, Mass spectrometry, whole-exome Sequencing

Molecular Microbiology

 

James Dunn, Ph.D.

Infectious Disease Testing

Real-time PCR, pyrosequencing

Molecular Neuropathology

 

Adekunle M. Adesina, M.D., Ph.D.

Neuropathology

FISH, Sanger sequencing, pyrosequencing, Western Blotting

Heading

Courses and Workshops

Terms

Item Term
'Dry-Labs' Applied Bioinformatics Course

Item Definition

A 10-course hands-on applied bioinformatics workshop intended to serve as basic training for clinical and biological data handling and database mining.

Item Term
Molecular Pathology Course

Item Definition

A didactic course offered by the molecular genetic pathology faculty for residents/fellows covering all aspects of molecular genetic pathology.

Item Term
Human Genetics Course

Item Definition

A course in the principles of human genetics offered by the faculty in the BCM Department of Molecular and Human Genetics

Item Term
Journal Club

Item Definition

Journal Club meetings are held over the course of the fellowship year.

Item Term
Molecular Genomics Tumor Board

Item Definition

Molecular Genomics Tumor Board meetings are held over the course of the fellowship year.

Content

Weekly conferences in pathology and genetics are included in the program.

Heading

Affiliates

Content

Affiliations with leading research and healthcare institutions in and around the Texas Medical Center, the world’s largest healthcare complex, provide access to an exceptionally diverse array of people and resources. Discover how our affiliations enhance our education programs.