Intracytoplasmic sperm injection or ICSI - often referred to as micromanipulation - is a revolutionary assisted reproduction technique used to treat male factor infertility. ICSI is used in conjunction with in vitro fertilization (IVF), meaning the eggs are mixed with sperm outside the body.

The procedure starts with retrieving eggs from the woman, then injecting a single sperm directly into each egg to achieve fertilization. The eggs are injected using specially designed microscopes, needles and micromanipulation equipment, in a very delicate procedure. The process is repeated for each egg. The eggs are then examined for signs of fertilization so they may be transferred into the uterus.