Research

2023 CTRID Publications

Master
Content

Castro P, Corredor G, Koyuncu C, Nordstrom LA, Tiji M, Leavitt T, Lewis JS Jr, Madabhushi A, Frederick MJ, Sandulache VC. Recurrent Oropharyngeal Squamous Cell Carcinomas Maintain Anti-tumor Immunity and Multinucleation Levels Following Completion of Radiation. Head Neck Pathol. 2023 Dec;17(4):952-960. doi: 10.1007/s12105-023-01597-z. Epub 2023 Nov 23. PMID: 37995073; PMCID: PMC10739687.

Ambrosi E, Curtis KN, Goli P, Patriquin MA, Arciniegas DB, Simonetti A, Spalletta G, Salas R. Resting-State Functional Connectivity of the Anterior Cingulate Cortex Among Persons With Mood Disorders and Suicidal Behaviors. J Neuropsychiatry Clin Neurosci. 2023 Nov 20:appineuropsych20220203. doi: 10.1176/appi.neuropsych.20220203. Epub ahead of print. PMID: 37981779.

Heisey HD, Qualls C, Villareal DT, Segoviano-Escobar MB, Nava MLD, Gatchel JR, Kunik ME. Depressive Symptoms are Associated With C-Reactive Protein in Older Adults With Obesity. J Geriatr Psychiatry Neurol. 2023 Nov 11:8919887231215041. doi: 10.1177/08919887231215041. Epub ahead of print. PMID: 37950647.

Gregori, G., Paudyal, A., Barnouin, Y., Celli, A., Segoviano-Escobar, M. B., Armamento-Villareal, R., Napoli, N., Qualls, C., & Villareal, D. T. (2023). Indices of sarcopenic obesity are important predictors of finite element analysis-derived bone strength in older adults with obesity. Frontiers in endocrinology, 14, 1279321. https://doi.org/10.3389/fendo.2023.1279321. PMID: 38027147. PMCID: PMC10660264.

Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, Zheng H, Richardson JP, Hube B, Naglik JR, Corry DB. Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Cell Rep. 2023 Oct 31;42(10):113240. doi: 10.1016/j.celrep.2023.113240. Epub 2023 Oct 17. PMID: 37819761.

Erice PA, Huang X, Seasock MJ, Robertson MJ, Tung HY, Perez-Negron MA, Lotlikar SL, Corry DB, Kheradmand F, Rodriguez A. Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via derepression of RORγt. bioRxiv [Preprint]. 2023 Oct 21:2023.10.12.562059. doi: 10.1101/2023.10.12.562059. PMID: 37905101; PMCID: PMC10614797.

Khatlani T, Pradhan S, Langlois K, Subramanyam D, Rumbaut RE, Vijayan KV. Opposing Roles for the α Isoform of the Catalytic Subunit of Protein Phosphatase 1 in Inside-Out and Outside-In Integrin Signaling in Murine Platelets. Cells. 2023 Oct 10;12(20):2424. doi: 10.3390/cells12202424. PMID: 37887268; PMCID: PMC10605409.

Goel R, Tse T, Smith LJ, Floren A, Naylor B, Williams MW, Salas R, Rizzo AS, Ress D. Framework for Accurate Classification of Self-Reported Stress From Multisession Functional MRI Data of Veterans With Posttraumatic Stress. Chronic Stress (Thousand Oaks). 2023 Sep 28;7:24705470231203655. doi: 10.1177/24705470231203655. PMID: 37780807; PMCID: PMC10540591.

Chang CY, Armstrong D, Corry DB, Kheradmand F. Alveolar macrophages in lung cancer: opportunities challenges. Front Immunol. 2023 Sep 26;14:1268939. doi: 10.3389/fimmu.2023.1268939. Erratum in: Front Immunol. 2023 Nov 06;14:1328927. PMID: 37822933; PMCID: PMC10562548.

Srivastava S, Arenkiel BR, Salas R. Habenular molecular targets for depression, impulsivity, and addiction. Expert Opin Ther Targets. 2023 Jul-Dec;27(9):757-761. doi: 10.1080/14728222.2023.2257390. Epub 2023 Sep 14. PMID: 37705488; PMCID: PMC10591939.

Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Hengstschläger M, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada LJ. SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells. Sci Transl Med. 2023 Sep 13;15(713):eade2581. doi: 10.1126/scitranslmed.ade2581. Epub 2023 Sep 13. PMID: 37703351.

Uddin MM, Saadatagah S, Niroula A, Yu B, Hornsby W, Ganesh S, Lannery K, Shuermans A, Honigberg MC, Bick AG, Libby P, Ebert BL, Ballantyne CM, Natarajan P. Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis. medRxiv [Preprint]. 2023 Sep 7:2023.09.05.23295093. doi: 10.1101/2023.09.05.23295093. PMID: 37732181; PMCID: PMC10508802.

Gollamudi J, Dasgupta SK, Thiagarajan P. Erythrophagocytosis in autoimmune immunoglobulin A-mediated hemolysis. Transfusion. 2023 Sep 5. doi: 10.1111/trf.17532. Epub ahead of print. PMID: 37668082.

Lichtenberger LM, Vijayan KV. Severe COVID-19 outcomes and hematological cancers: the clot thickens-are platelets the culprit? Transl Cancer Res. 2023 Sep 30;12(9):2425-2428. doi: 10.21037/tcr-23-672. Epub 2023 Aug 11. PMID: 37859735; PMCID: PMC10583002.

Kemnade JO, Florez M, Sabichi A, Zhang J, Jhaveri P, Chen G, Chen A, Miller-Chism C, Shaun B, Hilsenbeck SG, Hernandez DJ, Skinner HD, Sandulache VC. Phase I / II trial of metformin as a chemo-radiosensitizer in a head and neck cancer patient population. Oral Oncol. 2023 Oct;145:106536. doi: 10.1016/j.oraloncology.2023.106536. Epub 2023 Aug 8. PMID: 37562095.

Moukaddam N, Lamichhane B, Salas R, Goodman W, Sabharwal A. Modeling Suicidality with Multimodal Impulsivity Characterization in Participants with Mental Health Disorder. Behav Neurol. 2023 Aug 5;2023:8552180. doi: 10.1155/2023/8552180. PMID: 37575401; PMCID: PMC10423091.

Marin-Muller C, Li D, Lü JM, Liang Z, Vega-Martínez O, Crawford SE, Estes MK, Fisher WE, Chen C, Yao Q. Nanoparticle-Mediated Therapy with miR-198 Sensitizes Pancreatic Cancer to Gemcitabine Treatment through Downregulation of VCP-Mediated Autophagy. Pharmaceutics. 2023 Jul 28;15(8):2038. doi: 10.3390/pharmaceutics15082038. PMID: 37631252; PMCID: PMC10457905.

Gao D, Zhou Z, Ma R, Wu H, Nguyen T, Liu L, Dong J. Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia. Int J Mol Sci. 2023 Jul 22;24(14):11782. doi: 10.3390/ijms241411782. PMID: 37511541; PMCID: PMC10380474.

Soliman O, Wilde DC, Kemnade JO, Sabichi AL, Chen G, Chen A, Little SN, Huang AT, Hernandez DJ, Sandulache VC. Deployment of cisplatin in Veterans with oropharyngeal cancer: toxicity and impact on oncologic outcomes. Laryngoscope Investig Otolaryngol. 2023 Jul 14;8(4):895-902. doi: 10.1002/lio2.1115. PMID: 37621289; PMCID: PMC10446265.

Panda S, Maier G, Villareal DT. Targeting Energy Intake and Circadian Biology to Engage Mechanisms of Aging in Older Adults With Obesity: Calorie Restriction and Time-Restricted Eating. J Gerontol A Biol Sci Med Sci. 2023 Jun 16;78(Supplement_1):79-85. doi: 10.1093/gerona/glad069. PMID: 37325958; PMCID: PMC10272989.

Lin J, Ding X, Yang P, Liu S, Li Q, Cruz MA, Dong JF, Fang Y, Wu J. Force-induced biphasic regulation of VWF cleavage by ADAMTS13. Thromb Res. 2023 Sep;229:99-106. doi: 10.1016/j.thromres.2023.06.024. Epub 2023 Jul 1. PMID: 37421684.

Saadatagah S, Varughese MG, Nambi V. Coronary Artery Disease Risk Prediction in Young Adults: How Can We Overcome the Dominant Effect of Age? Curr Atheroscler Rep. 2023 Jun;25(6):257-265. doi: 10.1007/s11883-023-01106-1. Epub 2023 May 17. PMID: 37195598.

Aloi MS, Poblete GF, Oldham J, Patriquin MA, Nielsen DA, Kosten TR, Salas R. miR-124-3p target genes identify globus pallidus role in suicide ideation recovery in borderline personality disorder. Npj Ment Health Res. 2023;2(1):8. doi: 10.1038/s44184-023-00027-w. Epub 2023 Jun 5. PMID: 37712050; PMCID: PMC10500603.

Saadatagah S, Ballantyne CM. Clonal hematopoiesis of indeterminate potential and cardiovascular disease. Transl Res. 2023 May;255:152-158. doi: 10.1016/j.trsl.2022.08.013. Epub 2022 Sep 5. PMID: 36067904.

Kheradmand F, Zhang Y, Corry DB. Contribution of adaptive immunity to human COPD and experimental models of emphysema. Physiol Rev. 2023 Apr 1;103(2):1059-1093. doi: 10.1152/physrev.00036.2021. Epub 2022 Oct 6. PMID: 36201635; PMCID: PMC9886356.

Song J, Kim SJ, Gollamudi J, Thiagarajan P, Prchal JT. Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression. Blood Adv. 2023 Mar 14;7(5):712-717. doi: 10.1182/bloodadvances.2022008052. PMID: 36343116; PMCID: PMC9984957.

Gollamudi J, Dasgupta SK, Thiagarajan P. Erythrophagocytosis in autoimmune immunoglobulin A-mediated hemolysis. Transfusion. 2023 Sep 5. doi: 10.1111/trf.17532. Epub ahead of print. PMID: 37668082.

Kemnade JO, Florez M, Sabichi A, Zhang J, Jhaveri P, Chen G, Chen A, Miller-Chism C, Shaun B, Hilsenbeck SG, Hernandez DJ, Skinner HD, Sandulache VC. Phase I / II trial of metformin as a chemo-radiosensitizer in a head and neck cancer patient population. Oral Oncol. 2023 Oct;145:106536. doi: 10.1016/j.oraloncology.2023.106536. Epub 2023 Aug 8. PMID: 37562095.

Moukaddam N, Lamichhane B, Salas R, Goodman W, Sabharwal A. Modeling Suicidality with Multimodal Impulsivity Characterization in Participants with Mental Health Disorder. Behav Neurol. 2023 Aug 5;2023:8552180. doi: 10.1155/2023/8552180. PMID: 37575401; PMCID: PMC10423091.

Marin-Muller C, Li D, Lü JM, Liang Z, Vega-Martínez O, Crawford SE, Estes MK, Fisher WE, Chen C, Yao Q. Nanoparticle-Mediated Therapy with miR-198 Sensitizes Pancreatic Cancer to Gemcitabine Treatment through Downregulation of VCP-Mediated Autophagy. Pharmaceutics. 2023 Jul 28;15(8):2038. doi: 10.3390/pharmaceutics15082038. PMID: 37631252; PMCID: PMC10457905.

Gao D, Zhou Z, Ma R, Wu H, Nguyen T, Liu L, Dong J. Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia. Int J Mol Sci. 2023 Jul 22;24(14):11782. doi: 10.3390/ijms241411782. PMID: 37511541; PMCID: PMC10380474.

Soliman O, Wilde DC, Kemnade JO, Sabichi AL, Chen G, Chen A, Little SN, Huang AT, Hernandez DJ, Sandulache VC. Deployment of cisplatin in Veterans with oropharyngeal cancer: toxicity and impact on oncologic outcomes. Laryngoscope Investig Otolaryngol. 2023 Jul 14;8(4):895-902. doi: 10.1002/lio2.1115. PMID: 37621289; PMCID: PMC10446265.

Panda S, Maier G, Villareal DT. Targeting Energy Intake and Circadian Biology to Engage Mechanisms of Aging in Older Adults With Obesity: Calorie Restriction and Time-Restricted Eating. J Gerontol A Biol Sci Med Sci. 2023 Jun 16;78(Supplement_1):79-85. doi: 10.1093/gerona/glad069. PMID: 37325958; PMCID: PMC10272989.

Lin J, Ding X, Yang P, Liu S, Li Q, Cruz MA, Dong JF, Fang Y, Wu J. Force-induced biphasic regulation of VWF cleavage by ADAMTS13. Thromb Res. 2023 Sep;229:99-106. doi: 10.1016/j.thromres.2023.06.024. Epub 2023 Jul 1. PMID: 37421684.

Saadatagah S, Ballantyne CM. Clonal hematopoiesis of indeterminate potential and cardiovascular disease. Transl Res. 2023 May;255:152-158. doi: 10.1016/j.trsl.2022.08.013. Epub 2022 Sep 5. PMID: 36067904.

Kheradmand F, Zhang Y, Corry DB. Contribution of adaptive immunity to human COPD and experimental models of emphysema. Physiol Rev. 2023 Apr 1;103(2):1059-1093. doi: 10.1152/physrev.00036.2021. Epub 2022 Oct 6. PMID: 36201635; PMCID: PMC9886356.

Song J, Kim SJ, Gollamudi J, Thiagarajan P, Prchal JT. Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression. Blood Adv. 2023 Mar 14;7(5):712-717. doi: 10.1182/bloodadvances.2022008052. PMID: 36343116; PMCID: PMC9984957.

Kakavand H, Saadatagah S, Naderian M, Aghakouchakzadeh M, Jalali A, Sadri F, Amoli AI, Hosseini SH, Jenab Y, Pourhosseini H, Salarifar M, Talasaz AH. Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI). Naunyn Schmiedebergs Arch Pharmacol. 2023 Mar;396(3):557-565. doi: 10.1007/s00210-022-02368-3. Epub 2023 Mar 1. PMID: 36856810; PMCID: PMC9975441.

Koyuncu CF, Frederick MJ, Thompson LDR, Corredor G, Khalighi S, Zhang Z, Song B, Lu C, Nag R, Sankar Viswanathan V, Gilkey M, Yang K, Koyfman SA, Chute DJ, Castro P, Lewis JS Jr, Madabhushi A, Sandulache VC. Machine learning driven index of tumor multinucleation correlates with survival and suppressed anti-tumor immunity in head and neck squamous cell carcinoma patients. Oral Oncol. 2023 Jun 10;143:106459. doi: 10.1016/j.oraloncology.2023.106459. Epub ahead of print. PMID: 37307602.

Nguyen TC, Marini JC, Guillory B, Valladolid-Brown C, Martinez-Vargas M, Subramanyam D, Cohen D, Cirlos SC, Lam F, Stoll B, Didelija IC, Vonderohe C, Orellana R, Saini A, Pradhan S, Bashir D, Desai MS, Flores S, Virk M, Tcharmtchi H, Navaei A, Kaplan S, Lamberth L, Hulten KG, Scull BP, Allen CE, Akcan-Arikan A, Vijayan KV, Cruz MA. Pediatric Swine Model of Methicillin-Resistant Staphylococcus aureusSepsis-Induced Coagulopathy, Disseminated Microvascular Thrombosis, and Organ Injuries. Crit Care Explor. 2023 May 26;5(6):e0916. doi: 10.1097/CCE.0000000000000916. PMID: 37255626; PMCID: PMC10226618.

Yu W, Chen Y, Putluri N, Osman A, Coarfa C, Putluri V, Kamal AHM, Asmussen JK, Katsonis P, Myers JN, Lai SY, Lu W, Stephan CC, Powell RT, Johnson FM, Skinner HD, Kazi J, Ahmed KM, Hu L, Threet A, Meyer MD, Bankson JA, Wang T, Davis J, Parker KR, Harris MA, Baek ML, Echeverria GV, Qi X, Wang J, Frederick AI, Walsh AJ, Lichtarge O, Frederick MJ, Sandulache VC. Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. Br J Cancer. 2023 Jun;128(11):2013-2024. doi: 10.1038/s41416-023-02253-7. Epub 2023 Apr 3. PMID: 37012319; PMCID: PMC10205814.

Oluyomi AO, Mazul AL, Dong Y, White DL, Hartman CM, Richardson P, Chan W, Garcia JM, Kramer JR, Chiao E. Area deprivation index and segregation on the risk of HIV: a U.S. Veteran case-control study. Lancet Reg Health Am. 2023 Mar 21;20:100468. doi: 10.1016/j.lana.2023.100468. PMID: 36992707; PMCID: PMC10041556.

Elsea SH, Razjouyan J, Lee KM, Lynch JA, Martini S, Pandit LM. Association of Glucose-6-Phosphate Dehydrogenase Deficiency with Outcomes in US Veterans With COVID-19. JAMA Netw Open. 2023 Mar 1;6(3):e235626. doi: 10.1001/jamanetworkopen.2023.5626. PMID: 36988953; PMCID: PMC10061239.

Yanagisawa M, Han H, Pradhan S, Khatlani T, Subramanyam DVijayan KV. Protein Phosphatase 1 γ Modulates Steady-State BAD Phosphorylation and Murine Platelet Survival. Thromb Haemost. 2023 Mar 3. doi: 10.1055/a-2031-9709. Epub ahead of print. PMID: 36764308.

Chidambaram S, Chang SH, Sandulache VC, Mazul AL, Zevallos JP. Human Papillomavirus Vaccination Prevalence and Disproportionate Cancer Burden Among US Veterans. JAMA Oncol. 2023 Mar 2:e227944. doi: 10.1001/jamaoncol.2022.7944. Epub ahead of print. PMID: 36862390; PMCID: PMC9982736.

Herodes M, Anderson LJ, Shober S, Schur EA, Graf SA, Ammer N, Salas R, Marcelli M, Garcia JM. Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 Mar 1. doi: 10.1002/jcsm.13191. Epub ahead of print. PMID: 36860137.

Deepika F, Bathina S, Armamento-Villareal R. Novel Adipokines and Their Role in Bone Metabolism: A Narrative Review. Biomedicines. 2023 Feb 20;11(2):644. doi: 10.3390/biomedicines11020644. PMID: 36831180; PMCID: PMC9953715.

Groenewold NA, Bas-Hoogendam JM, Amod AR, Laansma MA, Van Velzen LS, Aghajani M, Hilbert K, Oh H, Salas R, Jackowski AP, Pan PM, Salum GA, Blair JR, Blair KS, Hirsch J, Pantazatos SP, Schneier FR, Talati A, Roelofs K, Volman I, Blanco-Hinojo L, Cardoner N, Pujol J, Beesdo-Baum K, Ching CRK, Thomopoulos SI, Jansen A, Kircher T, Krug A, Nenadić I, Stein F, Dannlowski U, Grotegerd D, Lemke H, Meinert S, Winter A, Erb M, Kreifelts B, Gong Q, Lui S, Zhu F, Mwangi B, Soares JC, Wu MJ, Bayram A, Canli M, Tükel R, Westenberg PM, Heeren A, Cremers HR, Hofmann D, Straube T, Doruyter AGG, Lochner C, Peterburs J, Van Tol MJ, Gur RE, Kaczkurkin AN, Larsen B, Satterthwaite TD, Filippi CA, Gold AL, Harrewijn A, Zugman A, Bülow R, Grabe HJ, Völzke H, Wittfeld K, Böhnlein J, Dohm K, Kugel H, Schrammen E, Zwanzger P, Leehr EJ, Sindermann L, Ball TM, Fonzo GA, Paulus MP, Simmons A, Stein MB, Klumpp H, Phan KL, Furmark T, Månsson KNT, Manzouri A, Avery SN, Blackford JU, Clauss JA, Feola B, Harper JC, Sylvester CM, Lueken U, Veltman DJ, Winkler AM, Jahanshad N, Pine DS, Thompson PM, Stein DJ, Van der Wee NJA. Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group. Mol Psychiatry. 2023 Jan 19. doi: 10.1038/s41380-022-01933-9. Epub ahead of print. PMID: 36653677.

Akowuah PK, Lema C, Rumbaut RE, Burns AR. A Low-Fat/Sucrose Diet Rich in Complex Carbohydrates Reverses High-Fat/Sucrose Diet-Induced Corneal Dysregulation. Int J Mol Sci. 2023 Jan 4;24(2):931. doi: 10.3390/ijms24020931. PMID: 36674448; PMCID: PMC9865780.

Ganugula R, Nuthalapati NK, Dwivedi S, Zou D, Arora M, Friend R, Sheikh-Hamad D, Basu R, Kumar MNVR. Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis. J Control Release. 2023 Jan;353:621-633. doi: 10.1016/j.jconrel.2022.12.012. Epub 2022 Dec 14. PMID: 36503070.

Martinez-Vargas M, Cebula A, Brubaker LS, Seshadri N, Lam FW, Loor M, Rosengart TK, Yee ARumbaut RECruz MA. A novel interaction between extracellular vimentin and fibrinogen in fibrin formation. Thromb Res. 2023 Jan;221:97-104. doi: 10.1016/j.thromres.2022.11.028. Epub 2022 Dec 7. PMID: 36495717; PMCID: PMC9726209.