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Research

2020 CTRID Publications

Master
Content

Bottazzi ME, Strych U, Hotez PJ, Corry DB. Coronavirus vaccine-associated lung immunopathology-what is the significance? Microbes Infect. 2020 Oct;22(9):403-404. doi: 10.1016/j.micinf.2020.06.007. Epub 2020 Jun 26. PMID: 32599077; PMCID: PMC7318931.

Bray MASartain SE, Gollamudi JRumbaut RE. Microvascular thrombosis: experimental and clinical implications. Transl Res. 2020 Nov;225:105-130. doi: 10.1016/j.trsl.2020.05.006. Epub 2020 May 23. PMID: 32454092; PMCID: PMC7245314.

Chen E, Kalavar A, Bui-Thanh NA, Opekun AR, White DL, Rosen D, Graham DY, Rumbaut RE, El-Serag HB, Jiao L. Serum Levels of Lipopolysaccharides and Risk of Advanced Colorectal Adenoma. Explor Res Hypothesis Med. 2020;5(2):47-52. doi: 10.14218/ERHM.2020.00001.

Chen X, Corry DB, Li E. Mechanisms of allergy and adult asthma. Curr Opin Allergy Clin Immunol. 2020 Feb;20(1):36-42. doi: 10.1097/ACI.0000000000000601. PMID: 31688153.

Colleluori G, Chen R, Turin CG, Vigevano F, Qualls C, Johnson B, Mediwala S, Villareal DTArmamento-Villareal R. Aromatase Inhibitors Plus Weight Loss Improves the Hormonal Profile of Obese Hypogonadal Men Without Causing Major Side Effects. Front Endocrinol (Lausanne). 2020 May 15;11:277. doi: 10.3389/fendo.2020.00277. PMID: 32499757; PMCID: PMC7243137.

Courson JA, Hanlon SD, Bray MA, Lam FW, Burns AR, Rumbaut RE. Serial block-face scanning electron microscopy: A provocative technique to define 3-dimensional ultrastructure of microvascular thrombosis. Thromb Res. 2020 Dec;196:519-522. doi: 10.1016/j.thromres.2020.10.008. Epub 2020 Oct 12. PMID: 33099176; PMCID: PMC7750836.

Cox AR, Chernis N, Bader DA, Saha PK, Masschelin PM, Felix JB, Sharp R, Lian Z, Putluri V, Rajapakshe K, Kim KH, Villareal DTArmamento-Villareal R, Wu H, Coarfa C, Putluri N, Hartig SM. STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity. Diabetes. 2020 Dec;69(12):2630-2641. doi: 10.2337/db20-0384. Epub 2020 Sep 29. PMID: 32994273; PMCID: PMC7679774.

Dasgupta SKThiagarajan P. Cofilin-1-induced actin reorganization in stored platelets. Transfusion. 2020 Apr;60(4):806-814. doi: 10.1111/trf.15747. Epub 2020 Mar 11. PMID: 32159862; PMCID: PMC7204406.

Dasgupta SK, Rivera S, Thiagarajan P. Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency. TH Open. 2020 Jan 23;4(1):e33-e35. doi: 10.1055/s-0040-1701238. PMID: 31984307; PMCID: PMC6978173.

Elhalawani H, Mohamed ASR, Elgohari B, Lin TA, Sikora AG, Lai SY, Abusaif A, Phan J, Morrison WH, Gunn GB, Rosenthal DI, Garden AS, Fuller CD, Sandulache VC. Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma. BMC Cancer. 2020 Sep 23;20(1):912. doi: 10.1186/s12885-020-07427-7. PMID: 32967643; PMCID: PMC7513300.

Gangaraju R, Song J, Kim SJ, Tashi T, Reeves BN, Sundar KM, Thiagarajan P, Prchal JT. Thrombotic, inflammatory, and HIF-regulated genes and thrombosis risk in polycythemia vera and essential thrombocythemia. Blood Adv. 2020 Mar 24;4(6):1115-1130. doi: 10.1182/bloodadvances.2019001379. PMID: 32203583; PMCID: PMC7094018.

Gosnell SN, Crooks KE, Robinson M, Oldham J, Patriquin MA, Fowler JC, Salas R. Subcortical brain morphometry of avoidant personality disorder. J Affect Disord. 2020 Sep 1;274:1057-1061. doi: 10.1016/j.jad.2020.05.127. Epub 2020 May 22. PMID: 32663932.

Gosnell SN, Meyer MJ, Jennings C, Ramirez D, Schmidt J, Oldham J, Salas R. Hippocampal Volume in Psychiatric Diagnoses: Should Psychiatry Biomarker Research Account for Comorbidities? Chronic Stress (Thousand Oaks). 2020 Feb 26;4:2470547020906799. doi: 10.1177/2470547020906799. PMID: 32440605; PMCID: PMC7219869.

Griffin DM, Bitner BR, Criss Ii Z, Marcano D, Berlin JM, Kent TA, Tour JM, Samson SL, Pautler RG. Use of a bioengineered antioxidant in mouse models of metabolic syndrome. Expert Opin Investig Drugs. 2020 Feb;29(2):209-219. doi: 10.1080/13543784.2020.1716216. Epub 2020 Jan 20. PMID: 31937152.

Gurwara S, Dai A, Ajami NJ, Graham DY, White DL, Chen L, Jang A, Chen E, El-Serag HB, Petrosino JF, Jiao L. Alcohol use alters the colonic mucosa-associated gut microbiota in humans. Nutr Res. 2020 Nov;83:119-128. doi: 10.1016/j.nutres.2020.09.004. Epub 2020 Sep 17. PMID: 33096423; PMCID: PMC7669629.

Hargrave A, Courson JA, Pham V, Landry P, Magadi S, Shankar P, Hanlon S, Das A, Rumbaut RESmith CW, Burns AR. Corneal dysfunction precedes the onset of hyperglycemia in a mouse model of diet-induced obesity. PLoS One. 2020 Sep 4;15(9):e0238750. doi: 10.1371/journal.pone.0238750. PMID: 32886728; PMCID: PMC7473521.

Hotez PJ, Corry DB, Strych U, Bottazzi ME. COVID-19 vaccines: neutralizing antibodies and the alum advantage. Nat Rev Immunol. 2020 Jul;20(7):399-400. doi: 10.1038/s41577-020-0358-6. PMID: 32499636; PMCID: PMC7271131.

Hotez PJ, Corry DB, Bottazzi ME. COVID-19 vaccine design: the Janus face of immune enhancement. Nat Rev Immunol. 2020 Jun;20(6):347-348. doi: 10.1038/s41577-020-0323-4. Epub 2020 Apr 28. PMID: 32346094; PMCID: PMC7187801.

Hotez PJ, Bottazzi ME, Corry DB. The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement. Microbes Infect. 2020 May-Jun;22(4-5):165-167. doi: 10.1016/j.micinf.2020.04.005. Epub 2020 Apr 17. PMID: 32305501; PMCID: PMC7162764.

Katsanos AH, Alexandrov AV, Mandava P, Köhrmann M, Soinne L, Barreto AD, Sharma VK, Mikulik R, Muir KW, Rothlisberger T, Grotta JC, Levi CR, Molina CA, Saqqur M, Palaiodimou L, Psaltopoulou T, Vosko MR, Moreira T, Fiebach JB, Rubiera M, Sandset EC, de Havenon A, Kent TA, Alexandrov AW, Schellinger PD, Tsivgoulis G; CLOTBUST-ER Trial Investigators. Pulse pressure variability is associated with unfavorable outcomes in acute ischaemic stroke patients treated with intravenous thrombolysis. Eur J Neurol. 2020 Dec;27(12):2453-2462. doi: 10.1111/ene.14447. Epub 2020 Aug 17. PMID: 32697894.

Knight JM, Wu Y, Mauk K, Weatherhead J, Anvari S, Kheradmand FCorry DB. Airway Mycosis and the Regulation of Type 2 Immunity. J Fungi (Basel). 2020 May 29;6(2):74. doi: 10.3390/jof6020074. PMID: 32485866; PMCID: PMC7344719.

Lam FW, Brown CA, Valladolid CEmebo DC, Palzkill TG, Cruz MA. The vimentin rod domain blocks P-selectin-P-selectin glycoprotein ligand 1 interactions to attenuate leukocyte adhesion to inflamed endothelium. PLoS One. 2020 Oct 13;15(10):e0240164. doi: 10.1371/journal.pone.0240164. PMID: 33048962; PMCID: PMC7553327.

Lewis PE, Poteet EC, Liu D, Chen C, LaBranche CC, Stanfield-Oakley SA, Montefiori DC, Ferrari G, Yao Q. CTLA-4 Blockade, during HIV Virus-Like Particles Immunization, Alters HIV-Specific B-Cell Responses. Vaccines (Basel). 2020 Jun 6;8(2):284. doi: 10.3390/vaccines8020284. PMID: 32517277; PMCID: PMC7349993.

Liu D, Zhou D, Sun Y, Zhu J, Ghoneim D, Wu C, Yao Q, Gamazon ER, Cox NJ, Wu L. A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk. Cancer Res. 2020 Oct 15;80(20):4346-4354. doi: 10.1158/0008-5472.CAN-20-1353. Epub 2020 Sep 9. PMID: 32907841; PMCID: PMC7572664.

Liu H, Luo J, Guillory B, Chen JA, Zang P, Yoeli JK, Hernandez Y, Lee II, Anderson B, Storie M, Tewnion A, Garcia JM. Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways. Oncotarget. 2020 Sep 1;11(35):3286-3302. doi: 10.18632/oncotarget.27705. PMID: 32934774; PMCID: PMC7476735.

Lurie E, Liu D, LaPlante EL, Thistlethwaite LR, Yao Q, Milosavljevic A. Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin. Oncogenesis. 2020 Jul 2;9(7):62. doi: 10.1038/s41389-020-00245-3. PMID: 32616712; PMCID: PMC7332500.

Morales-Mantilla DE, Huang X, Erice P, Porter P, Zhang Y, Figueroa M, Chandra J, King KY, Kheradmand FRodríguez A. Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System. J Vis Exp. 2020 Oct 22;(164):10.3791/61793. doi: 10.3791/61793. PMID: 33165327; PMCID: PMC7996447.

Mortus JR, Manek SE, Brubaker LS, Loor M, Cruz MATrautner BW, Rosengart TK. Thromboelastographic Results and Hypercoagulability Syndrome in Patients With Coronavirus Disease 2019 Who Are Critically Ill. JAMA Netw Open. 2020 Jun 1;3(6):e2011192. doi: 10.1001/jamanetworkopen.2020.11192. PMID: 32501489; PMCID: PMC7275245.

Nguyen TC. Thrombocytopenia-Associated Multiple Organ Failure. Crit Care Clin. 2020 Apr;36(2):379-390. doi: 10.1016/j.ccc.2019.12.010. PMID: 32172819.

Osae EA, Bullock T, Chintapalati M, Brodesser S, Hanlon S, Redfern R, Steven P, Smith CWRumbaut RE, Burns AR. Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production. Int J Mol Sci. 2020 Nov 20;21(22):8772. doi: 10.3390/ijms21228772. PMID: 33233559; PMCID: PMC7699756.

Valladolid CMartinez-Vargas MSekhar NLam F, Brown C, Palzkill T, Tischer A, Auton M, Vijayan KVRumbaut RENguyen TCCruz MA. Modulating the rate of fibrin formation and clot structure attenuates microvascular thrombosis in systemic inflammation. Blood Adv. 2020 Apr 14;4(7):1340-1349. doi: 10.1182/bloodadvances.2020001500. PMID: 32259201; PMCID: PMC7160269.

Weatherhead JE, Gazzinelli-Guimaraes P, Knight JM, Fujiwara R, Hotez PJ, Bottazzi ME, Corry DB. Host Immunity and Inflammation to Pulmonary Helminth Infections. Front Immunol. 2020 Oct 20;11:594520. doi: 10.3389/fimmu.2020.594520. PMID: 33193446; PMCID: PMC7606285.

White DL, Kunik ME, Yu H, Lin HL, Richardson PA, Moore S, Sarwar AI, Marsh L, Jorge RE. Post-Traumatic Stress Disorder is Associated with further Increased Parkinson's Disease Risk in Veterans with Traumatic Brain Injury. Ann Neurol. 2020 Jul;88(1):33-41. doi: 10.1002/ana.25726. Epub 2020 Apr 29. PMID: 32232880.