!

COVID-19 Response 

Access our COVID-19 Response homepage, with more information and resources during the COVID-19 pandemic, including what to do if you’re experiencing symptoms.

Graduate School of Biomedical Sciences

Genetics & Genomics Graduate Program Research

Master
Heading

Faculty Research by Organism

Media Component
Center for Disease Control and Prevention/James Archer
Bacteria can have a sweet tooth
Heading

Research Resources

Description

As you begin your career in research it is impossible to predict where your investigations will lead. Therefore, it is essential to have access to diverse resources. This includes not only equipment, but experienced individuals available to help you identify the resources you need and master their use.

Terms

Human Genome Sequencing Center

Item Definition

The Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) was established in 1996 when the National Human Genome Research Institute (NHGRI) designated Baylor College of Medicine as one of six pilot programs for the final phases of the Human Genome Project (HGP). Then in 1999, the Center was chosen as one of three sites from the pilot program to complete the HGP. 

Today, the BCM-HGSC employs more than 200 staff, and it occupies more than 36,000 square feet. The major activity of the BCM-HGSC is high-throughput DNA sequence generation and the accompanying analysis. The center currently operates multiple sequencing platforms (ABI Sanger and SOLid, 454 Life Sciences and Solexa/Illumina). The sequence data generated by these machines is analyzed in a complex bioinformatics pipeline, and the data are deposited regularly in the public databases at the National Center for Biotechnology Information (NCBI). This ensures that the worldwide research community has timely access to the data.

The BCM-HGSC is also involved in developing the next generation of DNA sequencing and bioinformatics technologies that will allow greater scientific advances in the future.

Advanced Technology Cores

Item Definition

Advanced technology core laboratories provide state-of-the-art instrumentation and technologies as well as consultation on experimental design, data analysis and training. Through the cores, you will not only gain access to tools and techniques that support your research, you will also receive training and mentorship in how to leverage these tools to develop innovative approaches to scientific challenges.

Core resources include laboratories for microarray analysis, next-generation sequencing, production of transgenic and knockout mice, mouse phenotyping, microscopy and imaging, confocal microscopy, high throughput screening, siRNA screening and other techniques.

Texas Medical Center

Item Definition

As a member of the Texas Medical Center, Baylor College of Medicine leverages the resources of the world’s largest medical complex. In addition to supporting collaborations with the many hospitals, schools and research institutes in the TMC, the Center also facilitates state of the art research through specialized resources, including the TMC Innovation Institute, the TMC Library, and TCM Health Policy Institute.

More Resources

Item Definition

The entities listed here are just a small sampling of the inter-disciplinary research resources at BCM. View more.

Media Component
Media
Content

Dr. Huda Zoghbi discusses her study featuring a three-pronged approach used in animal models to help subdue early events that occur in the brain long before symptoms of Alzheimer’s disease are evident.

Media Component
Cell Press
Media
Credit
Content

In this video, done in conjunction with the publication of their research in Cell Stem Cell, Dr. Margaret Goodell and M.D./Ph.D. student, Joanne Ino Hsu, discuss their findings that showed cytotoxic chemotherapies put patients at risk for future hematopoietic malignancies.

Media Component
Media
Content

Dr. Kjersti Aagaard, associate professor of obstetrics and gynecology, discussing her research on the vaginal microbiome in pregnancy as part of BCM's role in the Human Microbiome Project.

Media Component
Media
Content

Dr. Benjamin Arenkiel, McNair Scholar and associate professor of molecular and human genetics and neuroscience, discusses his findings published in Nature on acetylcholine's role in appetite control in mice.

Media Component
Media
Content

Dr. Marco Sardiello, assistant professor of molecular and human genetics at Baylor College of Medicine, describes the problem underlying Batten disease, a rare genetic and fatal neurodegenerative disorder linked to defects in cellular waste management.

Content

The scientific community is increasingly aware that an organism’s interactions with the millions of microbes in their bodies – the microbiome – can influence many of its functions, such as cognitive and metabolic activities and aging. Questions have also been raised about the role the genetic composition of the microbiome might be playing in longevity. In her lab at Baylor College of Medicine, Dr. Meng Wang, associate professor of molecular and human geneticsand the Huffington Center On Aging, investigated this possibility.

Read article