Coronary Artery Disease, Atherosclerosis, Ischemia


Theme Leaders

First Name
Middle Name
Last Name
Honorific Title
First Name
Middle Name
Last Name
Honorific Title
M.D., Ph.D.
Professor and Director, Basic Science and Translational Labs
First Name
Last Name
Honorific Title
M.D., Ph.D.
Professor and Vice Chair for Research

Current Clinical Projects


1. Magnetic resonance based leg muscle perfusion to assess leg function in peripheral arterial disease [NIH K23, PI: Brunner]

2. Comparative effectiveness of physicians versus non-physicians for the delivery of outpatient Diabetes care: Implications for access to care under the Affordable Care Act [ADA, PI: Virani]

3. Comparative effectiveness of physicians vs. non-physicians for CHD care: implications for the Affordable Care Act [AHA, PI: Virani]

4. Identifying epidemiological risk factors for abdominal aortic aneurysm [NIH, Baylor Co- PI: Hoogeveen]

5. ARIC Central Atherosclerosis Laboratory [NIH, PI: Ballantyne]

6. Study of Health Outcomes of Weight-Loss (Look AHEAD) Trial [NIH, PI: Foreyt]

7. ARIC Neurocognitive Study (ARIC-NCS) [NIH, Baylor Co-PI: Ballantyne]


Current Basic Research Projects


1. Monocyte activation and the role of CD11c in obesity-linked metabolic syndrome [NIH, PI: Wu]

2. T cells, macrophages, chemokines, and adiposopathy in diet-induced obesity [NIH, PI: Ballantyne]

3. Role of blood-borne fibroblast precursors in ischemic cardiomyopathy [NIH, PI: Entman]

4. LRP1 and endothelial function [NIH, PI: Pi]

5. Signaling in endothelial growth & angiogenesis [NIH, PI: Pi]

6. Natural Substance Derivative DHNB is A Novel Xanthine Oxidase Inhibitor (NIH R21, PI: Chen)

7. Molecular Surgeon Research Training on Vascular Disease (NIH T32, PI: Chen)

8. Stanniocalcin-1, a novel anti-inflammatory protein (NIH R01, PI: Sheikh-Hamad; Co-I: Chen)

9. Chronic kidney disease adversely influences vascular functions (NIH R01, PI: Cheng, Co-I: Chen)


Research Faculty


Ashok Balasubramanyam, M.D. - Ketosis-prone diabetes, myogenesis and insulin action, HIV associated lipodystrophy

John Belmont, M.D. - CV genetics, cardiovascular malformations and connective tissue disorders

Gerd Brunner, M.D. - Peripheral arterial disease, MR imaging

Robert Bryan, Ph.D. - Cerebrovascular circulation, EDHF in cerebral arteries, traumatic brain injury, K channels

Larry Chan, M.D. - Genetics of atherosclerosis and lipid disorders, novel therapies for diabetes

Chu-Huang (Mendel) Chen, M.D. Ph.D. - Electronegative LDL, angiogenesis0

Katarzyna Cieslik, Ph.D. - Cardiac mesenchymal progenitors

Miguel Cruz, M.D. - Von Willebrand factor, thrombosis

Mark Entman, M.D. - Molecular mechanisms of cardiac injury and repair, inflammatory signaling

John Foreyt, Ph.D. - Behavioral medicine research, coronary heart disease

John Gaubatz, MS - Lipoprotein metabolism

Craig Hartley, Ph.D. - Ultrasonic instrumentation for CV research, coronary blood flow

Sandra Haudek, Ph.D. - Circulating monocytic fibroblast precursors, cardiac hypertrophy

Ron Hoogeveen, Ph.D. - Sterol and lipid metabolism, dyslipidemia

Jimmy Howell, M.D. - Cardiothoracic surgery; ischemic heart disease

Peter Jones, M.D. - Lipid-modifying drugs, obesity, clinical trials

William Lagor, Ph.D. - Regulation of lipid and lipoprotein metabolism

Veronica Lenge De Rosen, M.D. - Imaging of coronary vasculature

Vijay Nambi, M.D. - Peripheral arterial disease, vascular imaging, cardiac prevention

Henry Pownall, Ph.D. - Adipogenesis, metabolic syndrome, lipoproteins

Anilkumar Reddy, Ph.D. - Doppler and physiological monitoring of small animals, hypertrophy, cardiac remodeling

Todd Rosengart, M.D. - Cardiac regeneration, cardiac gene therapy, angiogenesis

Rolando Rumbaut, M.D. Ph.D. - Microvascular thrombosis, leukocyte trafficking

C. Wayne Smith, M.D. - Mechanisms of leukocyte accumulation in inflammation and tissue injury

Addison Taylor, M.D. Ph.D. - Hypertension, clinical pharmacology JoAnn Trial, Ph.D. Origins of fibroblasts in cardiac injury healing

Vinod Vijayan, Ph.D. - Ser/Thr phosphatases in platelet and endothelial activation

Salim Virani, M.D. Ph.D. - Cardiac prevention, cholesterol management

Huaizhu Wu, M.D. - Inflammation associated with dyslipidemia and obesity