Amala Kaja, Ph.D.
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Amala Kaja, Ph.D.
Postdoctoral Associate
Positions
- Postdoctoral Associate
-
Medicine - Gastroenterology
Baylor College of Medicine
Education
- PhD from Southern Illinois University Carbondale
- 05/2022 - Carbondale, Illinois United States
- Molecular Biochemistry
- MSc from Mount Carmel College
- 05/2012 - Bengaluru, Karnataka India
- Biotechnology
- BSc from Mount Carmel College
- 05/2010 - Bengaluru, Karnataka India
- Biotechnology, Chemistry, Botany
Professional Statement
My goal is to gain a deeper understanding of ribosomes and proteostasis in the development of metaplasia and regeneration in the stomach. Specifically, I work with mouse and cellular models to dissect the role IFRD1, which Mills Lab has shown to be critical for ribosomal abundance under stress, and optimal cellular responses in various organs such as stomach and pancreas.Selected Publications
- "A novel UPS regulation of Sgf73/ataxin-7 that maintains the integrity of the co-activator SAGA in orchestrating transcription." ; Pubmed PMID: 37075097
- "An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function." ; Pubmed PMID: 31932480
- "An mRNA Capping Enzyme Targets FACT to the Active Gene To Enhance the Engagement of RNA Polymerase II into Transcriptional Elongation." ; Pubmed PMID: 28396559
- "Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export." ; Pubmed PMID: 30745412
- "Fine-Tuning of FACT by the Ubiquitin Proteasome System in Regulation of Transcriptional Elongation." ; Pubmed PMID: 27044865
- "Genome-Wide Regulations of the Preinitiation Complex Formation and Elongating RNA Polymerase II by an E3 Ubiquitin Ligase, San1." ; Pubmed PMID: 34661445
- "Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription.." ; Pubmed PMID: 33526453
- "Regulation of Antisense Transcription by NuA4 Histone Acetyltransferase and Other Chromatin Regulatory Factors." ; Pubmed PMID: 26755557
- "TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes." ; Pubmed PMID: 29712756
- "Two Distinct Regulatory Mechanisms of Transcriptional Initiation in Response to Nutrient Signaling." ; Pubmed PMID: 29141908
- "Ubiquitin-Proteasome System Regulation of an Evolutionarily Conserved RNA Polymerase II-Associated Factor 1 Involved in Pancreatic Oncogenesis." ; Pubmed PMID: 29023102
Languages
Hindi, Telugu, Kannada, French
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