RFA CPRIT PDX-Aim Core Developmental Grants

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  • Description: Full description of CPRIT PDX-Aim Core Developmental Grants

The CPRIT-funded Baylor College of Medicine Patient-Derived Xenograft and Advanced in vivo Models (PDX-AIM) Core Facility, will support up to six developmental research grants to help establish new PDX programs; utilization of PDX models for translational cancer research; and development of innovative strategies to enhance capabilities of murine PDX and chick chorioallantoic membrane (CAM) PDX and 3D tumor models.

While all submissions addressing these broad topics will be considered, particular areas of interest include: Application of murine PDX and CAM models to immunotherapy (e.g. development of “humanized” mouse PDX models, and other platforms suitable for testing immunotherapy approaches on human tumors); Development of novel strategies for delivery of candidate therapeutic agents to PDX or CAM-based 3D tumor models, and quantitative assessment of their delivery into tumor, and/or tumor response to therapy. Development of novel PDX and 3D tumor models for rare tumors and other cancer types where existing model systems are lacking or inadequate.  

Investigators must be Baylor faculty members (academic rank of instructor or above). While not a strict requirement, investigative teams are encouraged to include at least one new investigator (no R01 level funding) or junior faculty (instructor or assistant professor). Co-investigators and collaborators may be included as required by the project, but funds may not be used to support faculty salary. All PIs must be members of the  an L Duncan Cancer Center. Become a member.

Use of funds 
We will fund up to six grants of up to $50,000. Period of implementation is 12 months, beginning Dec. 3, 2018. A significant (>50%) portion of the awarded funds must be allocated to obtain services from the PDX-AIM core facility. Funds may not be used for faculty and administrative salary support, travel, subawards, consulting fees and equipment.  

For questions:
            Danielle Gilmore       danielle@bcm.edu

Please send completed applications as a single PDF to: 

            Charles Connolly        charles.connolly@bcm.edu
Key Dates
            RFA released:                         Oct. 1, 2018
            Applications received:            Oct. 22, 2018
            Notification of award:             Nov. 19, 2018
            Project start date:                   Dec. 3, 2018

Pilot Projects RFA

The Dan L Duncan Comprehensive Cancer Center is seeking to fund six (6) one-year pilot projects up to $50,000 each - to be awarded no later than January 2019.

Pilot projects this year should be focused on cancers which are problematic in our catchment area.  Interprogrammatic collaboration projects with a focus on any obesity related cancers including prevention, treatment, genetics, risk assessment, and epidemiology will be given the highest priority.

**Applications should be submitted by 5 p.m. on Monday, Nov. 5**

All cancer center members who have a tenured faculty appointment are eligible to apply.  

Indirect costs are not allowed and applications do not need to be submitted via BRAIN.

To apply, visit our online application system:  

*2019 Application link will be available starting Oct. 1**

If you have any questions, please contact Danielle Gilmore at (713) 798-2087 or email danielle@bcm.edu.  

NIH Grant Funding Opportunities

Current NIH funding opportunity announcements:

American Cancer Society Research Grants

The American Cancer Society awards research grants and fellowships to promising early-career scientists with unique hypotheses for cancer prevention and study, fostering the next generation of cancer research and creating a strong foundation of preliminary evidence to make scientific advancements. We also sponsor grants in support of training for health professionals seeking to develop their clinical expertise and/or their ability to conduct independent research.