BASIC: Baylor Advancing Sequencing into Childhood Cancer Care - Incorporation of Genomic Sequencing into Pediatric Cancer Care
Sharon Plon, M.D., Ph.D., Overall Co-Principal Investigator, Project 1 Co-Principal Investigator
D. William Parsons, M.D., Overall Co-Principal Investigator, Project 1 Co-Principal Investigator
Richard Gibbs, Ph.D., Project 2 Co-Principal Investigator
Christine Eng, M.D., Project 2 Co-Principal Investigator
Janet Malek, Ph.D., Project 3 Co-Principal Investigator
Richard Street, Jr., Ph.D., Project 3 Co-Principal Investigator
Center Project Personnel
Gutierrez AM, Robinson JO, Statham EE, Scollon S, Bergstrom KL, Slashinski MJ, Parsons DW, Plon SE, McGuire AL, Street RL. Portero versus Portador: Spanish Interpretation of Genomic Terminology during Whole Exome Sequencing Results Disclosure. Personalized Medicine 14(6), 2017: 503-514.
Malek, J, M Slashinski, JO Robinson, Gutierrez AM, Parsons DM, Plon SE, McCullough LB, McGuire AL. Parental Perspectives on Whole Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility. Journal of Clinical Oncology: Precision Oncology, 2017. [Epub ahead of print]
Parsons DW, Roy A, Yang Y, Wang T, Scollon S, Bergstrom K, Kerstein RA, Gutierrez S, Petersen AK, Bavle A, Lin FY, López-Terrada DH, Monzon FA, Hicks MJ, Eldin KW, Quintanilla NM, Adesina AM, Mohila CA, Whitehead W, Jea A, Vasudevan SA, Nuchtern JG, Ramamurthy U, McGuire AL, Hilsenbeck SG, Reid JG, Muzny DM, Wheeler DA, Berg SL, Chintagumpala MM, Eng CM, Gibbs RA, Plon SE. Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors. JAMA, 2016. [Epub ahead of print]
Scollon S, Bergstrom K, Kerstein R, Wang T, Hilsenbeck SG, Ramamurthy U, Gibbs RA, Eng CM, Chintagumpala MM, Berg SL, McCullough LB, McGuire AL, Plon SE, Parsons DW. Obtaining Informed Consent for Clinical Tumor and Germline Exome Sequencing of Newly Diagnosed Childhood Cancer Patients. Genome Medicine, 6(9), 2014: 69.
Clayton EW, McCullough LB, Biesecker LG, Joffe S, Ross LF, Wolf SM, for the Clinical Sequencing Exploratory Research (CSER) Consortium Pediatrics Working Group. Addressing the Ethical Challenges in Genetic Testing and Sequencing of Children. Am J Bioeth, 14(3), 2014: 3-9.
McGuire AL, Joffe S, Koenig BA, Biesecker BB, McCullough LB, Blumenthal-Barby JS, Caulfield T, Terry SF, Green RC. Ethics and Genomic Incidental Findings. Science, 340, 2013: 1047-1048.
McGuire AL, Robinson JO, Ramoni RB, Morley DS, Joffe S, Plon SE. Returning Genetic Research Results: Study Type Matters. Personalized Medicine, 10(1), 2013: 27-34.
Ramoni RB, McGuire AL, Robinson JO, Morley DS, Plon SE, Joffe S. Experiences and Attitudes of Genome Investigators Regarding Return of Individual Genetic Test Results. Genetics in Medicine, 15(11), 2013: 882-887.
McGuire AL, McCullough LB, Evans JP. The Indispensable Role of Professional Judgment in Genomic Medicine. JAMA, 309, 2013: 1465-1466.
Gutierrez AM, Robinson JO, Slashinski MJ, Statham EE, Street RL, Parsons DW, Plon SE, McGuire AL, McCullough LB. More than Just Translation: The Role of Medical Interpreters in the Disclosure of Whole Exome Sequencing Results for Spanish-Speaking Families. American Society for Bioethics and Humanities Annual Conference. Washington, DC. October 2016.
Malek, J. Culpability and Responsibility in Parents’ Experiences with Genome Sequencing for Pediatric Cancer Patients. American Society for Bioethics and Humanities Annual Conference. Washington, DC, October 2016.
Malek, J. Parental Perspectives on Whole Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility. American Society of Human Genetics Annual Meeting. Vancouver, CA, October 2016.
Gutierrez AM, Robinson JO, Statham EE, Slashinski MJ, Scollon S, Bergstrom KL, Street RL, Parsons DW, Plon SE, McGuire AL, McCullough LB. Lost in Translation: How Medical Interpreters Modify the Communication of Whole Exome Sequencing Results during Translation for Spanish-Speaking Families. National Society of Genetic Counselors Annual Education Conference. Seattle, WA. September/October 2016. Poster Presentation.
McCullough LB, Slashinski MJ, Wycliff J, McGuire AL, Street Jr. RL, Parsons DW, Plon SE. Do Pediatric Oncologists and Parents Experience Whole Exome Sequencing of Solid Organ Tumors in Children as a Disruptive Technology? The American Society for Bioethics and Humanities Annual Meeting, San Diego, CA. October 2014.