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  1. Baylor College of Medicine
  2. Research
  3. ATC Core Labs
  4. Optical Imaging and Vital Microscopy Core
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Optical Imaging and Vital Microscopy Core

Core News: New USPS stamps have Baylor College of Medicine connection

Microscopy Images: (Left) Oak Leaf Surface, (Right) Mouse Brain Neurons
(Left) Oak Leaf Surface - Credit: Jason Kirk; (Right) Mouse Brain Neurons - Credit: Jason Kirk, Optical Imaging & Vital Microscopy Core, Baylor College of Medicine

Dec. 13, 2022 – The U.S. Postal Service announced seven new stamp subjects for 2023, and this round there is a Houston connection. Two images produced by Jason Kirk, Director of the Optical Imaging & Vital Microscopy Core at Baylor College of Medicine, were chosen as part of the Life Magnified category. They are among 20 different images chosen by the USPS that capture details of life undetectable by the human eye. They are taken with microscopes and highly specialized photographic techniques that can capture the fine details found in nature and in many cases used in scientific research.

View Article

About the Core

The Optical Imaging and Vital Microscopy Core provides state-of-the-art instrumentation and cutting-edge imaging/image analysis tools for the research applications of a broad range of Baylor College of Medicine investigators. This core is dedicated to vital and intravital imaging of cellular processes within cells, intact tissue explants, developing embryos and functioning organs within the live animal. Our users are focused on a variety of applications such as understanding cell migration, optimizing angiogenic therapies, how blood flow influences development and cancer, immune cell recruitment, stem cell-niche interactions and cancer metastasis.

Microscopy Methods

The following microscopy methods are available through the Optical Imaging and Vital Microscopy Core. View information on each below:

Fluocells image

Fluorescence Microscopy

Learn more about the cornerstone of our imaging capabilities that can be used with a wide array of sample types.

LightSheet Microscopy

Learn more about how this novel 3D imaging technology can provide more insight into cleared whole mounts.

confocal image

Confocal Microscopy

Learn more about how our confocal microscopes can improve your fluorescence images.

Multi-Photon image

Multi-Photon Microscopy

Learn more about how our 2-Photon microscopes can help you see deeper into intact tissue.

microCT Image of Mouse Embryo

µCT (Micro Computed Tomography)

Learn more about how μCT technology can generate 3D images from unlabeled samples.

oivm opt 1

OPT (Optical Projection Tomography)

Learn more about how our custom built OPT solutions provide fast optical sectioning for biological specimens.

Need Imaging Services?

Visit our Services page to learn more about which service level is right for you.

Want to speak with OiVM Staff about your experiment? Fill out our User Request Form using the button below.

User Request Form
Kevin Roarty and Hongjiang Si
The image this month is a human breast cancer organoid in a collagen-based 3D matrix. The cancer cells (magenta) lack the noncanonical Wnt receptor, Ror2. The protein fibronectin (orange) is up-regulated and assembled by Ror2-deficient tumor cells, triggering the invasion, dissemination and survival of cancer cells during metastatic transit. Nuclei are depicted in gray.

From the Labs Image of the Month

November 2022 - The image is a human breast cancer organoid in a collagen-based 3D matrix. The image was captured on the Zeiss LSM 880 with Airyscan FAST Confocal Microscope in the Optical Imaging and Vital Microscopy Core at Baylor.

View Article
Optical Imaging and Vital Microscopy Core
  • Services
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    • Bruker SkyScan 1272 μCT Scanner
    • Image Processing/Analysis Workstations
    • Leica SP8 Confocal/Multi-Photon Microscope
    • OPT (Optical Projection Tomography)
    • Zeiss Axio Zoom v16 Stereo Microscope
    • Zeiss LSM 5 LIVE Confocal Microscope
    • Zeiss LSM 7 MP Multi-Photon Microscope
    • Zeiss LSM 780 Confocal Microscope
    • Zeiss LSM 880 with Airyscan FAST Confocal Microscope
    • Zeiss LightSheet Z.1 Microscope
  • Microscopy Methods
    • Confocal Microscopy
    • Fluorescence Microscopy
    • LightSheet Microscopy
    • Multi-Photon Microscopy
    • µCT (Micro Computed Tomography)
  • Request Form
  • Policies
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  • Core Staff

Contact OIVM

Phone 713–798–6486
Email oivm@bcm.edu

Optical Imaging and Vital Microscopy Core

One Baylor Plaza Cullen Building 113A/114A Houston, TX 77030

Core Hours

Regular Hours: 8 a.m. to 6 p.m. (Monday - Friday)
Core Approved Users: 24/7

Acknowledgement of Cores in Publications

Core name: Optical Imaging & Vital Microscopy Core
Personnel: Mary E. Dickinson, Ph.D., Senior Faculty Advisor; Jason M. Kirk, Academic Director; Chih-Wei Hsu, Ph.D., Imaging Specialist

Terms and Conditions

View and download the form for terms and conditions for use of core.

View and Complete Form

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