The Development, Disease Models & Therapeutics Ph.D. Program trains innovative, dedicated, passionate scientists who want to bridge the divide between basic scientific research and medicine.

Multi-Disciplinary Faculty

At BCM, faculty members have the freedom to select the programs that align with their research. Rather than be bound by the department or center into which they were hired, faculty members opt into participation in graduate programs.  This ensures that you will interact with faculty who bring diverse backgrounds and perspectives.

With over 150 faculty members, representing most of the departments and centers at BCM and many at our partner institutions, you will not only find mentors who share your interests but also colleagues who will expose you to new ideas and perspectives.

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Our Program

Our courses emphasize hands-on learning and our lab environments foster individual development and discovery-driven research. 

Research at Baylor College of Medicine (372x158)

Where will your Ph.D. take you?

From day one we encourage you to think deeply about your career choices. Wherever your ambition leads, you will receive the support you need to follow a path well worn by our alumni who have built successful careers across diverse endeavors. 

DDMT Research News

The Hippo pathway: tailor of the developing heart

The Hippo pathway is an inhibitor of adult heart regeneration; if you take the Hippo pathway away, then the heart can regenerate. But, can the Hippo pathway also play a role in the embryonic development of the heart? BCM researchers explored the role the Hippo pathway plays in regulating the development of a group of cardiac progenitor cells called epicardial cells.

There is more going on in DM1 than just alternative splicing

Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems.  In his laboratory at Baylor College of Medicine, Dr. Thomas A. Cooper is leading the way to better understand this rare but devastating condition.

The humble fruit fly continues to boost biomedical discovery

For more than 100 years, the humble fruit fly has been used to understand fundamental biological processes and has been a crucial tool for rapid preclinical gene discovery for myriads of human diseases. BCM researchers developed and made available a large versatile library of fruit flies that can be used to perform efficient and elegant in vivo gene-specific manipulations using the new protocol and gene-specific integration vector CRIMIC (CRISPR-Mediated Integrated Cassette).

credit: BCM-MGL
Changes in NLRP genes may be an answer to unexplained female infertility

Scientists estimate that as many as 15 percent of couples with infertility and 50 percent of women with recurrent pregnancy loss do not have a diagnosis for their condition. Some of these women may have recurrent loss of pregnancies with abnormally developing placentas, loss of the embryo before implantation, or, more rarely, having a baby with developmental disabilities. In some of these cases, mutations that lead to loss of function of genes in the NLRP family may provide answers to unexplained female infertility.

From the Labs

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