Department of Pediatrics

Center for Human Immunobiology


About the Center


A state-of-the-art research facility, Texas Children’s Center for Human Immunobiology specializes in the discovery of novel therapeutics and insights into the human immune system.

The facility is led by Dr. Carla McGuire Davis, associate professor of pediatrics at Baylor College of Medicine, chief, Division of Immunology, Allergy and Rheumatology and center director at Texas Children’s Hospital.

The center boasts a super resolution imaging microscope, the first of its kind that allows for imaging of the smallest of proteins inside of a single human cell along with state-of-the-art instrumentation to allow for cutting-edge biomedical research. Although the center is just completing construction, highly respected research has already been published and more is in the pipeline.


Center Research Areas and Services


The TECHCHI was established to identify novel mechanisms of human immunobiology and to translate these discoveries into novel clinical therapeutics. Faculty of both clinical and research backgrounds conduct state-of-the-art translational research in four core investigative areas: microscopy, flow cytometry, molecular and genomic analysis.

To provide abundant access to manipulated, ex vivo, human immune cells, TECHCHI also houses the first Biorepository of Immunologic Analysis in the Texas Medical Center, which enables mechanistic biological conclusions that mirror the in vivo physiology.

Availability of state-of-the-art technology in our four core investigative areas along with the BRIA allow for the ability to make scientific quantum leaps to elucidate the mechanisms of pediatric disease. With extraordinary efficiency, TECHCHI provides this resource not only within the institution, but broadly both national and international collaborators to generate synergy and enable discovery both inside and outside of the center.

Serving as a central hub with bi-directional spokes emanating throughout Texas Children's and Baylor, TECHCHI enables investigations and discoveries that will translate into high-impact biology and novel approaches to the diagnosis and treatment of pediatric disease.