Molecular Physiology and Biophysics News

Researchers find missplicing Scn5a alters cardiac functionSep 28, 2018
A new study shows that reproducing in mice the missplicing of gene Scn5a observed in patients with myotonic dystrophy type 1(DM1) recapitulates defects in cardiac function present in the patients.
INSiGHT identifies unique retinal regulatory genesAug 29, 2018
Researches at Baylor College of Medicine, Texas Children’s Hospital and the Hospital for Sick Children have developed a new platform called INSiGHT that enables them to uncover new regulators of retina neurons.
Signals in heart muscle cells linked to atrial fibrillationJun 4, 2018
Interfering with inflammatory signals produced by heart muscle cells might someday provide novel therapeutic strategies for atrial fibrillation.
Hippo pathway found essential to heart developmentApr 23, 2018
Using a technology that provides a ‘high-resolution view’ of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart.
Scorpion venom component may treat rheumatoid arthritisFeb 26, 2018
A group of researchers has found that one of the hundreds of components in scorpion venom can reduce the severity of rheumatoid arthritis in animal models, without inducing side effects associated with similar treatments.
Grant to fund study on gender differences in aortic diseaseJan 26, 2018
Baylor was selected to join the newly formed Strategically Focused Vascular Disease Research Network of the American Heart Association to focus on understanding the pathobiology underlying the differences in aortic disease between men and women.
Ciprofloxacin increases risk of tears, rupture in mouse aortas Nov 14, 2017
A team of researchers has found that a widely prescribed antibiotic increases the risk of tears and rupture on the main artery of the body, the aorta, in a mouse model of human aortic aneurysms and dissections.
Change in protein production essential to muscle functionAug 14, 2017
Researchers at Baylor College of Medicine have shed light on the process that guides the maturation of newborn muscles into adult, fully functional organs.
$27.9 million from NIH to support Baylor’s Knockout Mouse ProjectOct 12, 2016
NIH grant renewal supports Knockout Mouse Project that generates modified mice and establishes primary phenotype analysis as a resource for researchers world-wide. 
Tattoo therapy could ease chronic disease; skin-embedded nanoparticles may help control autoimmune diseasesSep 22, 2016
A proof-of-principle study shows that nanoparticles may help control autoimmune diseases.
Mouse study reveals genes essential for life and provides insights into human diseaseSep 14, 2016
Research by the International Mouse Phenotyping Consortium concludes that roughly a third of all genes in the mammalian genome are essential for life.
Recipients of 2016 DeBakey Research Award represent Baylor College of Medicine’s scientific excellenceMay 3, 2016
Five Baylor faculty members have received the Michael E. DeBakey Excellence in Research Award .
Human cells used to create disease model of fully functioning lipid system in mouse modelJun 17, 2015
Researchers have now created a disease model that resembles human mechanisms and acts as a fully functioning human lipid system within a mouse to specifically study hypercholesterolemia.
Baylor researchers share thoughts on current findings regarding heart repairMar 18, 2015
What can mend a broken heart? The answers are slowly revealing themselves in research labs studying what was once thought to be impossible. 
Researchers seek to make mini-guts that mimic lifeMar 16, 2015
A five-year, $5.1 million National Institutes of Health grant will help researchers engineer better “mini-guts” that are physiologically active.
Finding new path to treating rheumatoid arthritisSep 24, 2014
Baylor-led consortium's findings could point to new therapy for rheumatoid arthritis.
Baylor announces 2014 Michael E. DeBakey, M.D., Excellence in Research AwardsJul 2, 2014
The award, named in honor of the college’s first president and pioneering heart surgeon, was presented to the six recipients July 2.
Channel blocker treats asthma in the labApr 28, 2014
Baylor study findings could lead to potential new treatment for certain types of asthma.
Mechanical regulation of cell migration and vessel dynamics directs capillaries to form large vascular treesSep 5, 2013
Researchers at Baylor College of Medicine report that increases in blood flow induce small blood vessels called capillaries to fuse, increasing the size of the tube through which circulation moves and reducing resistance.
Cardiovascular research is focus of symposium at BCMApr 5, 2013
Symposium scheduled for Tuesday, April 9, in Cullen Auditorium and Rayzor Lounge, begins at 9 a.m.