Director: Susan Hilsenbeck, Ph.D.
Co-Director (Biostatistics): Hao Liu, Ph.D.
Co-Director (Cancer Bioinformatics): Chad Creighton, Ph.D.
Co-Director (Multi-Omic Bioinformatics): Cristian Coarfa, Ph.D.
Co-Director (Data Sharing): Neil McKenna, Ph.D.

Goal

It is our goal to provide state-of-the-art biostatistical, bioinformatics, and biomedical informatics support to the Dan L Duncan Comprehensive Cancer Center and Baylor College of Medicine investigators for clinical, translational and basic science research.

Organization

Areas of focus of the Biostatistics and Informatics Shared Resource (BISR) in analytics include biostatistics (led by Drs. Hilsenbeck, Liu, and Minard), bioinformatics and multi-omics (led by Drs. Creighton and Coarfa), data sharing (led by Dr. McKenna), and Biomedical Informatics (led by Dr. Hilsenbeck). BISR faculty members are listed here.

Services

The Biostatistics and Informatics Shared Resource provides a variety of services:

Biostatistics, Analytics and Bioinformatics

The Analytics group provides biostatistical and bioinformatic assistance to the Duncan Cancer Center investigators and can also collaborate with Baylor College of Medicine investigators. Services span the gamut from basic science through translational to clinical research:

  • Experimental design
  • Assistance with design & conduct of clinical trials
  • Data analysis of clinical and laboratory studies
  • Bioinformatic and integrative analysis of -omic data, using both investigator generated data and publicly available data
  • Statistical review for PRMS, DRC, etc.

We also provide consultation, project planning, assistance with grant preparation and related services. For more information visit our other webpages, put in a request through CrossLab, or contact one of our faculty.

Multi-Omics Data Analysis

The Multi-Omics Data Analysis services are operated as fee-for-service under the umbrella of the Biostatistics and Informatics Shared Resource (BISR) of the Duncan Cancer Center to assist biomedical investigators at Baylor College of Medicine and beyond.

The multi-omics data analysis services include:   

The data sharing services include:

  • Primary analysis of coding and non-coding transcriptomics
  • MS metabolomics and lipidomics
  • MS proteomics and RPPA proteomics
  • ChIP-Seq, ATAC-Seq, and bisulfite sequencing epigenomics
  • Data integrative analysis of data generated in Baylor core facilities and of publicly available data from national and international repositories

For more information on new services, pricing and contact information please visit the Multi-Omics Data Analysis and Data Sharing web site.

Data Sharing

Data Sharing services are operated as fee-for-service under the umbrella of the Biostatistics and Informatics Shared Resource (BISR) of the Duncan Cancer Center. 

Services include:

  • Data deposition and sharing in national repositories 
  • Cross-reference membership
  • Training in data deposition for novel or specialized repositories

For more information on new services, pricing and contact information please visit the Multi-Omics Data Analysis and Data Sharing web site.

Biomedical Informatics & Research IT

The Biomedical Informatics Group provides support for data management and web development for biobanks, clinical trials and custom projects as well as enterprise HPC and licensing of commercial software at value discounted rates.

We also provide consultation, project planning, assistance with grant preparation and related services. Individual licenses for scientific software such as SAS, SPSS, Ingenuity IPA, and Oncoming RPE are available at reduced rates and can be purchased directly at On The Hub (SAS, SPSS), by contacting licensing@breastcenter.tmc.edu (IPA, Oncoming), or by visiting the lab link.

Requests for service are initiated in several ways, but virtually always involve personal contact and discussion. Investigators with an existing collaboration with a resource member and need for the same support, should contact the member directly. Investigators with new projects may contact a member or one of the co-directors. Projects may also be undertaken at the request of center leadership. For more information

Site Licenses for Scientific Software

Individual licenses for scientific software such as SAS, SPSS, Ingenuity IPA, and Oncomine RPE are available at reduced rates and can be purchased directly at On The Hub (SAS, SPSS), by contacting licensing@breastcenter.tmc.edu (IPA, Oncoming), or by visiting the lab link.

Education and Training

BISR members serve as trainee mentors and teach in a number of courses. Visit our Training and Education page for more information.