April 24, 2023: Ivo Yonchev joins us from the University of Sheffield as a postdoctoral associate! Welcome to the Eagen Lab!
April 18, 2023: Yi-Hung Chen joins us as a graduate student in the Development, Disease Models & Therapeutics Graduate Program at Baylor College of Medicine! Welcome to the Eagen Lab!
January 16, 2023: Dr. Kyle Eagen is grateful to receive an R Accelerated Award from the Alex's Lemonade Stand Foundation (ALSF) for Childhood Cancer. This generous funding will support research projects in the lab about how chromosome 3D structure is reprogrammed in cancer and how to intervene in this reprogramming for therapeutic purposes. Read more about the project on the ALSF website and blog.
November 1, 2022: John Collette joins us as a research associate from a neighboring lab at Baylor College of Medicine. Welcome to the Eagen Lab!
June 6, 2022: Chris Ponne and Quan Le joins us as a research technicians! Chris is from Kenyon College and Quan joins us from Yale University. Welcome to the Eagen Lab!
May 23, 2022: Cate Hawkins joins us from the University of Dayton as a research technician! Welcome to the Eagen Lab!
April 11, 2022: We are thrilled to contribute a news and views article on two new exciting papers in Nature Genetics! Highlights includes how BET proteins, BRD4 in particular, contribute to cohesin-dependent chromatin looping and cohesin-independent genome compartmentalization. View article.
Nov. 17, 2021: Congratulations to the Foltz Lab at Northwestern University for their new paper "UBR7 acts as a histone chaperone for post-nucleosomal histone H3"! We were happy to contribute to this story! View paper.
Nov: 1, 2021: We are thrilled to announce that the Eagen Lab has moved to Baylor College of Medicine! We are now members of the Department of Molecular and Cellular Biology and are also affiliated with the Center for Precision Environmental Health, the Stem Cells and Regenerative Medicine Center, and the Center for Cell and Gene Therapy.
Aug.18, 2021: Dr. Kyle Eagen is honored to be awarded a generous First-Time, Tenure-Track Faculty Award from the Cancer Prevention & Research Institute of Texas. This CPRIT grant will allow the lab to pursue high-risk, high-reward projects at the interface of nuclear organization and cancer. View article.
Jan. 15, 2021: Our review with collaborator Chris French at Brigham and Women's Hospital presenting a mechanistic model for how fusion with NUT supercharges BRD4's function as a transcriptional coactivator, including our recent discovery of a novel nuclear subcompartment, is published in Oncogene! View article.
April 2, 2020: We are thrilled to share that the first paper from our lab has been published in Molecular Cell! We're excited to report that we've identified a novel nuclear subcompartment formed by chromatin hyperacetylation. Congratulations to Celeste Rosencrance, Haneen Ammouri, Qi Yu, and Tiffany Ge for their dedication to this project! View article.
Oct, 30, 2019: Our review summarizing the most recent genomics methods to study chromosome architecture is published as a Technology of the Month Article in Trends in Biochemical Sciences! Congratulations to Tiffany Ge and Celeste Rosencrance on the beautiful graphics! View article.
Feb. 1, 2019: Our review, "Principles of Chromosome Architecture Revealed by Hi-C", has been selected as part of the "Best of Trends" series, celebrating reviews published in 2018. Read about the selection and the review.
May 14, 2018: Our lab's review synthesizing recent studies of chromosome architecture using Hi-C is published in Trends in Biochemical Sciences and featured on the cover! View article.
Oct. 5, 2017: Dr. Kyle Eagen is honored to receive a 2017 NIH Director's Early Independence Award and deeply appreciative of the NIH Common Fund for supporting our research! View article.