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Chunmei Wang Lab Publications

Yu M, Feng B, Bean JC, Zhao Q, Yang Y, Liu H, Li Y, Eappen BP, Liu H, Tu L, Conde KM, Wang M, Chen X, Yin N, Threat DA, Xu N, Han J, Gao P, Zhu Y, Hadsell DL, He Y, Xu P, He Y, Wang C. Suppression of hypothalamic oestrogenic signal sustains hyperprolactinemia and metabolic adaptation in lactating mice. Nat Metab. 2025;7(4):759-77. Epub 20250410. doi: 10.1038/s42255-025-01268-z. PubMed PMID: 40211044.

Zhang N, Yu M, Zhao Q, Feng B, Deng Y, Bean JC, Liu Q, Eappen BP, He Y, Conde KM, Liu H, Yang Y, Tu L, Wang M, Li Y, Yin N, Liu H, Han J, Threat DA, Xu N, Smiley T, Xu P, Chen L, Zeng T, He Y, Wang C. Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females. Mol Metab. 2025 Mar; 93:102108. PMID: 39909189; PMCID: PMC11849645.

Ye H, Yang X, Feng B, Luo P, Torres Irizarry VC, Carrillo-Sáenz L, Yu M, Yang Y, Eappen BP, Munoz MD, Patel N, Schaul S, Ibrahimi L, Lai P, Qi X, Zhou Y, Kota M, Dixit D, Mun M, Liew CW, Jiang Y, Wang C, He Y, Xu P. 27-Hydroxycholesterol acts on estrogen receptor a expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior. Sci Adv. 2024 Jul 12; 10(28):eadi4746. PMID: 38996023; PMCID: PMC11244552.

Feng B, Liu H, Mishra I, Duerrschmid C, Gao P, Xu P, Wang C, He Y. Asprosin promotes feeding through SK channel-dependent activation of AgRP neurons. Sci Adv. 2023 02 22; 9(8):eabq6718. PMID: 36812308; PMCID: PMC9946352.

Yu M, Bean JC, Liu H, He Y, Yang Y, Cai X, Yu K, Pei Z, Liu H, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Scarcelli NA, Xu P, He Y, Xu Y, Wang C. SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis. Cell Biosci. 2022 Oct 9;12(1):170. doi: 10.1186/s13578-022-00907-2. PubMed PMID: 36210455; PubMed Central PMCID: PMC9549684.

Pei Z, He Y, Bean JC, Yang Y, Liu H, Yu M, Yu K, Hyseni I, Cai X, Liu H, Qu N, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Potts CH, Scarcelli NA, Yan Z, Xu P, Wu Q, He Y, Xu Y, Wang C. Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Front. Endocrinol. 2022 August.

Wang C, Zhou W, He Y, Yang T, Xu P, Yang Y, Cai X, Wang J, Liu H, Yu M, Liang C, Yang T, Liu H, Fukuda M, Tong Q, Wu Q, Sun Z, He Y, Xu Y. AgRP neurons trigger long-term potentiation and facilitate food seeking. Transl Psychiatry. 2021 Jan 5;11(1):11. doi: 10.1038/s41398-020-01161-1. PubMed PMID: 33414382; PubMed Central PMCID: PMC7791100.

He Y, Xu P, Wang C, Xia Y, Yu M, Yang Y, Yu K, Cai X, Qu N, Saito K, Wang J, Hyseni I, Robertson M, Piyarathna B, Gao M, Khan SA, Liu F, Chen R, Coarfa C, Zhao Z, Tong Q, Sun Z, Xu Y. Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance. Nat Commun. 2020 May 1;11(1):2165. doi: 10.1038/s41467-020-15982-7. PubMed PMID: 32358493; PubMed Central PMCID: PMC7195451.

Wang C, Xu Y. Mechanisms for Sex Differences in Energy Homeostasis. J Mol Endocrinol. 2019 Feb;62(2):R129-R143. doi: 10.1530/JME-18-0165. Epub 2019 Feb 1. Review. PubMed PMID: 31130779; PubMed Central PMCID: PMC6528488.

Wang C, He Y, Xu P, Yang Y, Saito K, Xia Y, Yan X, Hinton A Jr, Yan C, Ding H, Yu L, Shu G, Gupta R, Wu Q, Tong Q, Lagor WR, Flores ER, Xu Y. TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis. Nat Commun. 2018 Apr 18;9(1):1544. doi: 10.1038/s41467-018-03796-7. PubMed PMID: 29670083; PubMed Central PMCID: PMC5906443.

Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, Saha PK, Lee ME, Phillips KJ, Jain M, Jia P, Zhao Z, Farias M, Wu Q, Milewicz DM, Sutton VR, Moore DD, Butte NF, Krashes MJ, Xu Y, Chopra AR. Asprosin is a centrally acting orexigenic hormone. Nat Med. 2017 Dec;23(12):1444-1453. doi: 10.1038/nm.4432. Epub 2017 Nov 6. PubMed PMID: 29106398; PubMed Central PMCID: PMC5720914.

Chunmei Wang Lab
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Chunmei Wang Lab

Children's Nutrition Research Center
1100 Bates Ave Rm 8020 Houston, TX 77030
CNRC from the south with green house

USDA/ARS Children's Nutrition Research Center

The Wang Lab is part of the USDA/ARS Children's Nutrition Research Center which houses laboratories, state-of-the-art equipment, a greenhouse, observation labs, research volunteer accommodations, a metabolic kitchen, and an elite group of research scientists.

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