Pediatric Diabetes and Endocrinology Clinical Studies

The aim of this study is to identify individuals at risk for type 1 diabetes, seeking relatives of individuals with type 1 diabetes.

The aim of this study is to test the type 1 diabetes genetic risk scores for predication of type 1 diabetes and selection of candidates for prevention trials.

The aim of this study is to utilize immunologic biomarkers, in particular a variant-specific IA-2 autoantibodies, for type 1 diabetes prediction.

This is an observational study involving a one-time blood draw and data collection. The goal is to identify new biomarkers and biological signatures associated with type 1 diabetes to improve understanding of its development and support future prevention and treatment strategies.

This randomized control trial is testing a strengths-based peer support program for young adults with type 1 diabetes who are transitioning from pediatric to adult diabetes healthcare. 

The aim of this study is to mitigate health disparities by addressing social needs and behavioral health early in the course of type 1 diabetes. 

The EMPoWER Study randomized clinical trial is a strengths-based behavioral intervention delivered to youth with type 1 diabetes (age 10 to 13) and their parents.

Adults with T2D have very low levels of glutathione, which puts them at risk of harm from oxidative stress. Could children with diabetes also have low glutathione levels, and is this the reason why diabetes harms children so quickly? 

This study aims to investigate arginine metabolism and the effect of arginine administration in children with type 2 diabetes compared to healthy controls. 

Adolescents and young adults (ages 12-18 years; normal weight and overweight) with and without type 2 diabetes are needed for a research study to investigate the effect of obesity and childhood onset diabetes on bone health and risk of heart disease in youth.

PASS-56321 is an eight-week, randomized, clinical research study that aims to explore the benefits of increasing Physical Activity and Stopping evening Snacks on youth with prediabetes!

The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a national effort to learn about the causes of type 2 diabetes in children. It is a multi-center study at 15 locations across the United States.

This study looks at the relationship of sleep habits and sleep quality in youth with their bone health and factors that may influence this relationship such as nutrition, physical activity and hormones.

The purpose of RADIANT study is to discover and classify new and unusual forms of diabetes.

The aim of this study is to test type 1 diabetes genetic risk scores in combination with other characteristics present at diabetes diagnosis to accurately and timely classify diabetes type in racially/ethnically diverse youth. 

To evaluate the proportion of obese patients with genetic defects in the melanocortin-4 receptor (MC4R) pathway who achieve a clinically meaningful reduction in body weight in response to setmelanotide after an initial response to open-label treatment.

The goal of this study is to establish a database of pediatric patients with early-onset obesity who have been phenotypically well-characterized through a variety of standardized assessments.

Adapt an evidence-based diabetes prevention program for delivery via telehealth and to test the feasibility of this study among Hispanic adolescents (12-16 years) with obesity.

The goal of this study is to investigate the prevalence of dysglycemia with continuous glucose monitoring (CGM) obtained during pulmonary exacerbations, both outpatient and inpatient, in youth with cystic fibrosis (CF).

The objective of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas System (BP) relative to usual care, which includes continuous glucose monitoring (CGM) over a 13-week period.