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Houston, Texas

A full range of modern neurosurgical specialties and techniques are provided by top BCM neurosurgery specialists.
Department of Neurosurgery
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Vladimir V. Didenko, M.D., Ph.D.


Vladimir V. Didenko, MD

Associate Professor

Departments of Neurosurgery and Molecular and Cellular Biology

Medical School

  • Moscow Medical University, Moscow, Russia


  • Institute of General Pathology, Heart Pathophysiology Division, Academy of Medical Science, Moscow, Russia


  • Institute of General Pathology, Academy of Medical Sciences, Moscow, Russia
  • Moscow University, Laboratory of Physico-Chemistry of Biomembranes, Moscow, Russia
  • Karolinska Institutet, Stockholm, Sweden
  • Baylor College of Medicine, Department of Molecular and Cellular Biology & Huffington Center on Aging, Houston, TX

Primary Neurosurgical Interests

  • Research: Neural cell injury and programmed cell death; cell cycle regulation in aging brain cells; mechanisms of age-related neural cell death; methods to detect and control programmed cell death in vivo; development and application of nucleic acid-based nanoprobes; molecular machines, nanoparticles, DNA-enzymes, self-assembling molecular systems and sensors made of carbon nanotubes.

Professional Associations

  • Society for Neuroscience
  • American Chemical Society
  • American Society for Cell Biology
  • American Assoc. for Advancement of Sciences
  • New York Academy of Sciences
  • Fellow of the Royal Society of Medicine, UK

Contact Information:

  • Veterans Affairs Medical Center
    2002 Holcombe Blvd.
    Research Bldg 109, Room 204
    Houston, TX 77030
    Phone: 713-794-7572
    Fax: 713-794-7095

Free Links to selected Publications

In vitro Assembly of Semi-artificial Molecular Machine and its Use for Detection of DNA Damage. J Vis Exp. 59:e3628, 2012. doi: 10.3791/3628. (

Fluorescent Probes Detecting the Phagocytic Phase of Apoptosis: Enzyme-Substrate Complexes of Topoisomerase and DNA. Molecules, 16: 4599–4614, 2011. (view article)

5'OH DNA breaks in apoptosis and their labeling by topoisomerase-based approach. Methods Mol Biol.682:77-87, 2011. (view article)

In situ ligation simplified: using PCR fragments for detection of double-strand DNA breaks in tissue sections. Methods Mol Biol.682: 65-75, 2011. (view article)

In situ ligation: a decade and a half of experience. Methods Mol Biol.682:49-63, 2011. (view article)

In situ labeling of DNA breaks and apoptosis by T7 DNA polymerase. Methods Mol Biol.682:37-48, 2011. (view article)

Horseradish peroxidase-driven fluorescent labeling of nanotubes with quantum dots. BioTechniques, 40:298-302, 2006. (view article)

Visualization of individual single-walled carbon nanotubes by fluorescent polymer wrapping. Nano Lett. 5: 1563-1567, 2005 (view article)

Polyethyleneimine as a transmembrane carrier of fluorescently labeled proteins and antibodies. Analytical Biochem. 344:168-173, 2005. (view article)

Special Issue on Apoptosis: (view article)

Free public access links to books:

Book 1: In Situ Detection of DNA Damage

Book 2: Fluorescent Energy Transfer Nucleic Acid Probes

Book 3: DNA Damage Detection In Situ, Ex Vivo, and In Vivo

Free access link showing 19 papers for which free text is available:

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