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Department of Medicine

Atherosclerosis and Vascular Medicine Research


Faculty in the Division of Atherosclerosis and Vascular Medicine conduct basic science, clinical, and translational research on the mechanisms, diagnosis, treatment, and prevention of dyslipidemia, atherosclerosis, cardiovascular disease, and other cardiometabolic disorders.

Research facilities include both core and individual faculty labs, and research projects range from investigator-initiated experiments to the large epidemiological Atherosclerosis Risk in Communities (ARIC) Study to multisite clinical trials of preventive therapies.


Basic Science Research


Basic scientists in the division investigate the mechanisms underlying lipid abnormalities, atherosclerosis pathophysiology, and cardiometabolic disease. Researchers use biochemistry, cell and molecular biology, genetics, molecular biophysics, and transgenic animal models to provide insights into the disease process that may eventually lead to improvements in human healthcare practice and preventive strategies.

Cardiovascular disease is multifactorial, and individual faculty labs focus on complementary components of this complex disorder, developing and implementing innovative approaches that utilize diverse techniques to explore and expand the evolving concepts of cardiometabolic disease.


Clinical Research


Division faculty members design and perform clinical research projects in centralized labs and centers as well as in the Lipid Metabolism and Atherosclerosis Clinic. Ongoing studies include NIH-supported projects and industry-sponsored research.

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