About the Lab

We are working on the interface of developmental and reproductive biology, optical engineering, and computational modeling and analysis to understand mechanisms regulating normal and abnormal developmental processes. Our approaches combine live embryo manipulation protocols, mouse models of congenital defects, state-of-the-art functional optical coherence tomography technology, confocal microscopy and advanced computational analysis. Through development of innovative optical imaging methods and using them in mouse models of human disorders, we study dynamic functional aspects of these disorders.

Latest Lab News!

May 11, 2019 – Andrew Lopez received a travel award to Society for Developmental Biology (SDB) meeting in Boston July 26-30 this year! 

May 9, 2019 – Our research has been highlighted on the Advanced Science News website: Optical Coherence Microscopy Provides New Insight into Infertility

Apr. 12, 2019 - Congrats to Andrew Lopez for receiving 1st place Outstanding Platform Presentation Award at the Texas Forum for Reproductive Sciences (TFRS) in College Station, TX 

Jan. 20, 2019 – $2.5M NIH R01 grant “In vivo analysis of mammalian fertilization” has been funded; PI: Irina Larina 

Jan. 9, 2019 – Congratulations to Emma Moore for her first-author publication in Journal of Biophotonics “Staging mouse preimplantation development in vivo using optical coherence microscopy"

Dec. 19, 2018 – Warm welcome to Zheng-Chen Yao, who joined our lab as a research technician 

Nov. 8, 2018 – Congrats to Andrew Lopez on receiving American Heart Association predoctoral fellowship!

Sept. 1, 2018 – $2.8M NIH R01 grant “Biomechanics of early mammalian cardiogenesis” has been renewed for additional five years; PI: Irina Larina

May 10, 2018 – Congrats to Andrew Lopez for receiving a travel award to Society for Developmental Biology (SDB) Meeting in Portland July 20-24 this year!

April 26, 2018 - Andrew Lopez successfully passed his qualifying and is now a Ph.D. candidate!

March 19, 2018 - CONGRATS to Shang Wang for his new Development paper titled, "In vivo three-dimensional tracking of sperm behaviors in the mouse oviduct"!

January 2018 – Shang Wang’s recent publication “Biomechanical assessment of myocardial infarction using optical coherence elastography” was widely covered by news outlets, including a news release by The Optical Society “Biomechanical Mapping Method Aids Development of Therapies for Damaged Heart Tissue”Optics & Photonics NewsScienceDaily, TMC NewsHouston Public MediaEurekAlert!, Medical Xpressoptics.org, ScienceNewsline, Felix, Medical Design Technology, and Medical Device Network.

Support Our Research

Supporting our research will contribute to advanced understanding of infertility and congenital defects, which can potentially contribute to development of better strategies for prevention, monitoring and treatment of these disorders. If you would like to support our efforts, please visit the Baylor College of Medicine Ways to Give site.