Irina Larina Lab


Support Our Research


Supporting our research will contribute to advanced understanding of infertility and congenital defects, which can potentially contribute to development of better strategies for prevention, monitoring and treatment of these disorders. If you would like to support our efforts, please visit the Baylor College of Medicine Ways to Give site.


Lab Members


Zheng-Chen Yao, Andrew Lopez, Dr. Shang Wang, and Dr. Irina Larina


Current Projects


Live dynamic analysis of cardiac development and congenital defects in mouse embryos.

Live imaging of mammalian pre-implantation events.

In vivo micro-scale tomography of ciliary behavior.


Latest Lab News


July 13, 2021 – Our study "In vivo dynamic 3D imaging of oocytes and embryos in the mouse oviduct" has been published in Cell Reports journal and highlighted by multiple news outlets!

June 18, 2021 – Congrats to Dee Scully for receiving third place platform presentation award at the Texas Forum for Reproductive Sciences!

April 17, 2021 – Dee Scully delivered a great talk at the Pathology and Immunology Trainee Symposium and received 1st place postdoc presentation award!

March 1, 2021 – Tian Xia successfully passed his qualifying exam and is now a Ph.D. candidate!

Feb. 23, 2021 – Andrew Lopez successfully defended his Ph.D. dissertation! Congratulations, Dr. Lopez!

Jan. 21, 2021 – We are happy to welcome Dr. Deirdre (Dee) Scully all the way from Ireland joining the lab as a postdoc.

Nov. 23, 2020 – Welcome our to new postdoc Dr. Kohei Umezu coming from Japan and joining us in the middle of a pandemic.

Sept. 1, 2020 – Congrats to Andrew Lopez for his first-author paper in Journal of Cardiovascular Development and Disease "Cardiodynamic Imaging in Mouse Embryos with Optical Coherence Tomography."

July 1, 2020 – Congrats to Andrew Lopez for his first-author paper in Journal of Biophotonics "Optogenetic cardiac pacing in cultured mouse embryos under imaging guidance."

June 1, 2020 – We welcome new QCB graduate student Tian Xia!

Nov. 15, 2019 – Andrew Lopez received Deborah K. Martin Award, the highest honor presented by the Graduate School to one student in recognition of outstanding research accomplishments, personal character and intellectual leadership.

July 15, 2019 – All the best to Shang Wang as he sets up his own new research lab at the Stevens Institute of Technology as a tenure-track assistant professor!

May 11, 2019 – Andrew Lopez received a travel award to Society for Developmental Biology (SDB) meeting in Boston July 26-30 this year!

May 9, 2019 – Our research has been highlighted on the Advanced Science News website: Optical Coherence Microscopy Provides New Insight into Infertility

May 1, 2019 – Congrats to Andrew Lopez for his first-author paper and front cover image selection in Biomedical Optics Express "Second harmonic generation microscopy of early embryonic mouse hearts."

April 12, 2019 - Congrats to Andrew Lopez for receiving 1st place Outstanding Platform Presentation Award at the Texas Forum for Reproductive Sciences (TFRS) in College Station, TX

Jan. 20, 2019 – $2.5M NIH R01 grant “In vivo analysis of mammalian fertilization” has been funded; PI: Irina Larina

Jan. 9, 2019 – Congratulations to Emma Moore for her first-author publication in Journal of Biophotonics “Staging mouse preimplantation development in vivo using optical coherence microscopy"

Dec. 19, 2018 – Warm welcome to Zheng-Chen Yao, who joined our lab as a research technician

Nov. 8, 2018 – Congrats to Andrew Lopez on receiving American Heart Association predoctoral fellowship!

Sept. 1, 2018 – $2.8M NIH R01 grant “Biomechanics of early mammalian cardiogenesis” has been renewed for additional five years; PI: Irina Larina

May 10, 2018 – Congrats to Andrew Lopez for receiving a travel award to Society for Developmental Biology (SDB) Meeting in Portland July 20-24 this year!

April 26, 2018 - Andrew Lopez successfully passed his qualifying and is now a Ph.D. candidate!

March 19, 2018 - CONGRATS to Shang Wang for his new Development paper titled, "In vivo three-dimensional tracking of sperm behaviors in the mouse oviduct"!

Jan. 2018 – Shang Wang’s recent publication “Biomechanical assessment of myocardial infarction using optical coherence elastography” was widely covered by news outlets, including a news release by The Optical Society “Biomechanical Mapping Method Aids Development of Therapies for Damaged Heart Tissue”Optics & Photonics NewsScienceDailyTMC NewsHouston Public MediaEurekAlert!Medical, ScienceNewsline, FelixMedical Design Technology, and Medical Device Network.