About the Lab

Function and integrity of the skeleton require proper bone patterning, growth, remodeling and repair. Our research program focuses on several of these processes and how they can be affected in pathological conditions. We combine the use of genetic mouse models, pharmacological approaches and gain or loss-of-function strategies to interrogate the role of specific genes in these processes in health and diseases and to uncover new therapeutic targets to better prevent or manage skeletal conditions including osteoporosis, recalcitrant bone healing or breast cancer metastasis to the skeleton.

Active Funding

1R01 AG055394-01 (Elefteriou) July 15, 2017 - May 31, 2022
1R21AR072483-01A1 (Nyman, Elefteriou) April 4, 2018 - March 31, 2020