About the Lab
We study rare childhood diseases using medical genetics, genomics, and Drosophila models.
The long-term goal of the Wangler lab is to improve understanding of the molecular pathogenesis of Mendelian disease by merging clinical observations, genomics, and model organisms. We are pursuing gene discovery efforts using the Drosophila model organism to identify the underlying molecular pathology.
Dr. Wangler is a physician-scientist and pediatrician at the Texas Children’s Hospital and co-director of the Model Organism Screening Center (MOSC) of the Undiagnosed Diseases Network (UDN). The Wangler lab and collaborators make up the Drosophila core of the MOSC.
The Wangler lab has also taken on functional validation cases in Drosophila for the Baylor College of Medicine Center for Precision Medicine.
Dr. Michael Wangler, a physician-scientist and pediatrician, studies Mendelian diseases using genomics and functional studies in Drosophila. Research interests are Pediatric genetics and Peroxisomal disorders.
View a listing of the current research projects for the Wangler Lab
View a listing of research publications from the lab.
Duncan Neurological Research Institute (Lab)
Jan and Dan Duncan Neurological Research Institute
1250 Moursund Street, Suite 1050
Houston, TX 77030
Phone: (832) 822-1240