Furqan Fazal Lab


About the Lab

Media Component
Furqan Fazal Lab
The landscape of RNA subcellular localization revealed by APEX-seq (Fazal et al., Cell 2019). The Fazal lab develops and applies quantitative tools and approaches to study the organization of RNAs within cells. Artwork by Leah Bury.

The Fazal Lab is a young laboratory focusing on systematically interrogating the subcellular transcriptomes of mammalian cells and characterizing the scope, regulation, and function of subcellular localization, particularly at the systems and organismal level. We use a variety of biochemical, biophysical, imaging, genomic and computational approaches to investigate the sequence-function relationship dictating RNA localization.

Funding and Projects

CPRIT First-time Tenure-track Faculty Award
$2,000,000, Five years of funding covering equipment and research expenses
Project Title: Defining new mechanisms and regulation of RNA localization in cancer

NIH K99/R00 Pathway to Independence Award (2019-2024)
$1,025,000, Five years of funding covering salary and research expenses
Project Title: Revealing principles of subcellular RNA localization by proximity labeling