March 30, 2025 – Jon won the first place presentation award at the Clonal Hematopoiesis P01 retreat
March 18, 2025 – Xiangguo’s paper on guanine metabolism in leukemia was published in Nature Communications
March 1, 2024 – Jacob Tao joined our lab. Welcome Jacob!
January 15, 2024 – Nina and Yuki’s paper was published in Nature Communications
July 1, 2023 – Yi-Chen Huang joined our lab. Welcome Yi-Chen!
Oct. 10, 2022 – Mengdie Feng joined our lab as a new postdoc. Welcome Mengdie!
April 18, 2022 – Yuki Kageyama joined our lab as a new postdoc. Welcome Yuki!
Feb. 2, 2022 – The lab celebrated Nina' Tseng's thesis defense and becoming Dr. Tseng!
Jan. 2, 2022 – Kristen Andreozzi and Mackenzie Smith joined the lab. Welcome Kristen and Mackenzie!
Jan. 27, 2022 – Ken Eagle, Yajian Jiang, and Xiangguo Shi's paper establishing that leukemia specific super enhancer of SEPHS2 promotes selenoprotein synthesis in AML was published in Cell Stem Cell. View paper.
Aug. 10, 2021 – Rebecca Murdaugh's paper on the role of Hira in hematopoietic stem cell differentiation was published in Stem Cell Reports. View paper.
July 21, 2021 – Xiangguo Shi's paper on the role of NAD+ metabolism in leukemia stem cells was published in Science Advances. View paper.
June 25, 2021 – The lab celebrated Rebecca's thesis defense. Congratulations Rebecca!
Jan. 22, 2020 – The lab celebrated Yajian's thesis defense. Congratulations Dr. Jiang!
Dec. 12, 2019 – Yajian Jiang's paper establishing the role of AMPK in linking acetyl-coA homeostasis to BRD4 recruitment was published in Blood. View paper.
Aug. 15, 2019 - Tianyuan Hu's paper on demonstrating how an oncogene PRDM16 transforms progenitor cells to leukemia stem cells was published in Blood. View paper.
June 27, 2019 - Tianyuan Hu's paper on the role of Bmi1 in hematopoietic stem cell niche was published in Stem Cell Reports. View paper.
June 10, 2019 - A graduate student in the Developmental Biology program Jonathan Tiessen joined the lab. Welcome Jon!
April 27, 2018 - The lab celebrated Rich's success on defending your dissertation and becoming Dr. Chapple!
Congratulations Rich Chapple
Feb. 1, 2018 - Rich Chapple’s paper describing how estrogen activates the unfolded protein response in hematopoietic stem cells was published in eLife! View paper
May 8, 2018: Xiangguo Shi’s paper on multiplex CRISPR editing of hematopoietic stem cells to model myeloid malignancies was published in Experimental Hematology! View paper.
May 30, 2018: Rich Chapple and Nina (Yu-jung) Tseng’s paper on lineage tracing of hematopoietic stem cells was published in Blood Advances! View paper.