Advances in DNA sequencing technologies have led to ‘metagenomic’ approaches that allow the analysis of genetic material derived from complete microbial communities harvested from natural environments thereby providing a largely unbiased view of the human microbiome as well as the microbiomes of other animals and environmental niches.
The CMMR houses five primary faculty and over 50 students, postdoctoral fellows, research associates and staff. These investigators are currently pursuing nearly 300 individual microbiome-related projects with more than 150 collaborators worldwide, with this number increasing daily.
In the laboratories of CMMR faculty, researchers are developing molecular and bioinformatics tools and resources to advance numerous clinical and basic research projects pertaining to the organisms that comprise the microbiome, the genetic makeup of these bacteria, viruses and eukaryotes, and how these commensal microorganisms interact with human cells and tissues during the course of life.
Recognizing the necessity and value of networking with investigators who leverage valuable platforms and who have access to valuable cohorts or sample collections, our services are highly collaborative, with diverse projects that include microbial ecology and model systems, immunology, cell biology, genetics and genomics, metabolomics, epidemiology, and systems engineering.
The CMMR is one of the first fully translational microbiome research centers." - Dr. Joseph Petrosino, CMMR Director