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  1. Baylor College of Medicine
  2. Research
  3. ATC Core Labs
  4. Mouse Metabolism and Phenotyping Core
  • Services
    • Imaging
    • Blood Serum/Plasma Analysis
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Mouse Metabolism and Phenotyping Core

About the Core

The Mouse Metabolism and Phenotyping Core is a comprehensive fee-for-service rodent phenotyping core providing investigators with a wide variety of state of the art equipment and techniques. We work to standardize key methodologies, and to expedite comprehensive research analyses on diseases related to cancer, cardiovascular dysfunction, metabolic disorders, mouse models of human disease and drug studies.

Mouse Metabolic and Phenotyping Core Lab

CLAMS

Monitor indirect calorimetry parameters, food/water consumption, activity and core body temp using CLAMS.

Vevo F2

Vevo F2

Perform mouse or rat ultrasound imaging with our VisualSonics Vevo F2 Ultrasound. (Acquired with NIH S10 OD032380).

Mediso NanoScan

Mediso NanoScan PET/SPECT/CT

Perform mouse or rat 3D X-Ray CT and PET SPECT nuclear-medicine based imaging.

Seahorse

Seahorse

Assay Mitochondrial biogenesis using XFe-96 Seahorse.

IVIS Lumina X5

IVIS Lumina X5

Perform in vivo Luminesce/Fluorescence/X-Ray imaging in mice or rats.

Policies

The Mouse Metabolism and Phenotyping Core recognizes that preservation of raw and annotated data is essential to high quality research. The following policy is provided to help communicate the core’s data storage and archival policy so that users of the core can make appropriate plans for the efficient retrieval of their data and long term archival.

User-Accessible machine output from core equipment–Several pieces of core equipment are readily accessible to trained users and provide output files that are immediately accessible. It is the responsibility of the users of the equipment to promptly transfer and back-up their files from these instruments on the dates of data collection. As a courtesy to users, the core will attempt to maintain the data on these systems for the previous six months; however, periodic purges of data may be required in order to provide sufficient memory for continued data collection.

Machine output requiring core personnel for file transfer–Some pieces of core equipment are either restricted in their access, or in the ability of general users to directly access their data. These instruments are listed below with their respective policies.

Bruker 7T MRI –Imaging files will be transferred from the instrument to aninternet-cloud storage solution (box.bcm.edu). A cloud folder will be created for the deposit of the files and the contents will be shared with the users that have requested the images. A summary log indicating which files are associated with which samples will also be provided. This cloud folder is anticipated to be available to users for at least five years from the date of data collection.

Mediso PET/SPECT/CT–Imaging files (including the raw images and the 3d reconstructed images) will be maintained on the core’s dicom server and may be transferred to an internet-cloud storage solution upon request (box.bcm.edu). Files are anticipated to remain available to users for at least five years from the date of data collection.

Fujifilm Visual Sonics Ultrasound Vevo F2–Raw imaging files will be backed up and maintained on the core’s raid configured network attached storage for archival purposes. This archive will contain images for at least 5 years from the date of data collection. The images will also be made available within one week of their acquisition on the assigned analysis work station for each core user. From the workstation users are able to perform analysis and annotation and may back-up both raw and analyzed/annotated data from this system. In order to maintain sufficient storage for ongoing studies, data older than two years may need to be purged from these workstations. The archived raw data will still be available upon request, and users will receive 14 days of notice to allow for back-up of data before purging.

Metabolism Assay Equipment(includes CLAMS and metabolism services) –Raw data are maintained within the core for at least five years from the date of data collection. Where file size permits, data will be transmitted to users via email or through an internet-cloud storage solution (box.bcm.edu). Users can also make appointments with the core staff to transfer the data onto physical media.

Data collected by and analyses performed by the core–Data collected by the core as part of a specifically funded core project will be maintained on the core’s raid configured network attached storage. These include all raw data, analyzed data, and reports or data summaries attributable to the project. Additionally, these files will be made available to the user requesting the study via an internet-cloud storage solution (box.bcm.edu). The data will continue to be made available for at least five years from the completion of the study.

Mouse Metabolism and Phenotyping Core
  • Services
    • Imaging
    • Blood Serum/Plasma Analysis
    • Cardiopulmonary
    • Metabolism
    • Cellular Metabolism
    • Glucose Metabolism
    • Lipid Metabolism
    • Whole Body Metabolism
    • Other Tests
    • Challenges
    • Surgical and Anesthesia Services
    • Assistance Services
  • Fees
  • Order Service
  • Publications
  • Core Staff

Contact

Email mmpc-atc@bcm.edu

Mouse Metabolism and Phenotyping Core

One Baylor Plaza ABBR (R630) and Taub Building (T001) Houston, TX 77030

Acknowledgement of Cores in Publications

Core Name:
Mouse Metabolism and Phenotyping 
Core Personnel:
Christopher Ward, Ph.D., Core Director
Pradip Saha, Ph.D., Co-Director
Grants supporting the core:
NIH UM1HG006348, NIH R01DK114356, NIH R01HL130249

Service Scheduling

The iLab website is used to request services. All services are scheduled and tracked using iLab.

Learn More

Terms and Conditions

View and download the form for terms and conditions for use of core.

View and Complete Form

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