Positions

Professor
Anesthesiology
Baylor College of Medicine
Houston, TX, US

Education

Postdoctoral Fellowship at Duke University
PhD from University Of British Columbia
M.S. from University Of Alabama
BS from University Of Alabama

Professional Statement

Our laboratory studies communications between the gut bacteria, the gut, and the brain during normal and pathological states. These studies include hypertension, stroke, aging, Alzheimer’s disease, and cerebral small vessel disease.

A second line of investigation involves the control of cerebral circulation during normal and pathological states. Current projects involve the interaction between cerebrovascular endothelium and smooth muscle.

Selected Publications

  • Durgan DJ, Ganesh BP, Cope JL, Ajami NJ, Phillips SC, Petrosino JF, Hollister EB, Bryan RM. "Role of the Gut Microbiome in Obstructive Sleep Apnea-Induced Hypertension." Hypertension. 2016;67(2):469-474.
  • Adnan S, Nelson JW, Ajami NJ, Venna VR, Petrosino JF, Bryan RM, Durgan DJ. "Alterations in the gut microbiota can elicit hypertension in rats." Physiol Genomics. 2017;49:96-104.
  • Durgan DJ, Crossland RF, Bryan RM. "The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea." J Cereb Blood Flow Metab. 2017;37:2806-2819.
  • Lloyd EE, Durgan DJ, Martini SR, Bryan RM. "Pathological effects of obstructive apneas during the sleep cycle in an animal model of cerebral small vessel disease." Hypertension. 2015;66:913-917.