Zhi Tan, M.D., Ph.D.
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Zhi Tan, M.D., Ph.D.
Assistant Professor
Positions
- Assistant Professor
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Pathology
Baylor College of Medicine
Houston, US
- Assistant Professor
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Center for Drug Discovery
Baylor College of Medicine
- Assistant Professor
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Pharmacology and Chemical Biology
Baylor College of Medicine
Addresses
- Jan and Dan Duncan Neurological Research Institute Building - 6th Floor (Office)
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Houston, TX 77030
United States
Education
- MD from Wuhan University
- 06/2012 - Wuhan, Hubei China
- PhD from University of Texas MD Anderson and UT Health Graduate School of Biomedical Science
- 12/2018 - Houston, Texas United States
Websites
Selected Publications
- Yajuan Li*, Zhi Tan*, Yaohua Zhang*, et al. (*Equal Contribution) "A noncoding RNA modulator potentiates phenylalanine metabolism in mice." Science. 2021 Aug;
- Ram K Modukuri*, Zhifeng Yu*, Zhi Tan*, Hai Minh Ta*, et al. (*Equal contribution) "Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections." PNAS. 2022 May;
- Peiwen Chen, Wen-Hao Hsu, Andrew Chang, Zhi Tan, Zhengdao Lan, Ashley Zhou, Denise J Spring, Frederick F Lang, Y Alan Wang, Ronald A DePinho "Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor MicroenvironmentCLOCK in Tumor Immunity." Cancer Discovery. 2020 Mar;
- Jacqulyne P Robichaux, Yasir Y Elamin, Zhi Tan, et al. "Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer." Nature Medicine. 2018 May;
- Mingxing Teng, Damian W Young, Zhi Tan "The Pursuit of Enzyme Activation: A Snapshot of the Gold Rush." Jounal of Medicinal Chemistry. 2022 Oct;
- Baoli Hu, Qianghu Wang, Y Alan Wang, Sujun Hua, Charles-Etienne Gabriel Sauvé, Derrick Ong, Zheng D Lan, Qing Chang, Yan Wing Ho, Marta Moreno Monasterio, Xin Lu, Yi Zhong, Jianhua Zhang, Pingna Deng, Zhi Tan, et al. "Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth." Cell. 2016 Nov;
- Chengcao Sun*, Youqiong Ye* , Zhi Tan*, et al. (* Equal Contribution) "Tumor-associated nonmyelinating Schwann cell–expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion." Science advance. 2023 Jan; Pubmed PMID: 36724291
- Zhi Tan, Thomas Garcia. "SLO3 in the fast lane: The latest male contraceptive target with a promising small-molecule inhibitor." PNAS. 2023 Feb; Pubmed PMID: 36791103
Funding
- First Time Tenture Track Faculty Award - #RR220039
- $2,000,000.00 ( 06/01/2022 - 06/01/2027 ) Grant funding from CPRIT
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