Mechanisms of Protein-Energy-Wasting in Chronic Kidney Disease - #5R01AR063686
$299,306.00 (07/01/2013 - 04/30/2018)
Grant funding from NIH/NIDDK
The project is directed at identifying a new mechanism for CKD -induced "protein-energy wasting" which is frequently associated with increased morbidity and mortality. The PI has engineered transgenic mouse models specifically designed to identify the cause of protein-energy wasting. The pathway PI proposed might be manipulated pharmacologically to prevent or reverse protein-energy wasting in CKD.